649 research outputs found
Marangoni‐Driven Patterning in Polymer Thin Film Supported on Shrinking Substrate for Resolution Enhancement
No full textThe Marangoni effect causes liquids to flow toward localized regions with higher surface tension. In a polymer thin film, the flow induced by photochemically programmed surface tension gradients can be harnessed to manufacture patterned surfaces. Patterned polymer films are particularly useful for controlling adhesion, improving photonic device efficiency, and directing cellular alignment. In general, a broader range of accessible pattern resolutions and/or aspect ratios ensures a broader range of applications. However, because of the process flow for pattern formation, the final pattern periodicity of the Marangoni-driven features matches that of the initially prescribed surface energy pattern. To achieve better resolution without using sophisticated and complex tools, a shrinking (or pre-strained) polymer film was used as a substrate. The shrinking substrate could “contract or densify” the features along the substrate plane. Consequently, the resolution of the patterns formed on the shrinking substrate was improved by the shrinkage rate of the substrate compared with those formed on the non-shrinking substrate (i.e., silicon wafer).
Evaluation of accelerated test parameters for migration testing of food packaging
No full textThis thesis focused on determining or evaluating accelerated analytical protocol for detecting potential migrants from food contact surface of conventional ink printed and/or UV/EB cured food packaging to food. Due to “offset transfer” effect of food packaging system, the need of fast and precise migration testing protocols emerged, which are in compliance with FDA recommendation and FDA guideline. In this study, variations of migration levels by change of testing parameters such as agitation, temperature, time, simulated solvent, and solvent volume/surface area ratio were investigated. Furthermore, the comparison studies of migration level between water soluble and insoluble compounds were performed. Single-side cell extraction and gas chromatography-mass spectrometry (GC-MS) were used to detect migrant compounds. Through the conclusion, 24-hour accelerated migration testing protocols are suggested and evaluated, which are regarded to be equivalent to the FDA recommended testing protocols.M.S.Includes bibliographical referencesBy Shin Bae Ki
[[alternative]]CREATE YOUR OWN FATE :TWO RUNNER’S LIFE STORY
No full text[[abstract]]CREATE YOUR OWN FATE :
TWO RUNNER’S LIFE STORY
Master’s Thesis, June, 2006 Wu, Bae-Chyi
Advisor: Liu, I-Min Ph.D.
Abstract
“Running is the Way for Runner to Achieve Self-Realization and Mental Fortitude”. This article explored two runners’ experiences of marathon running and presented through the telling of life’s stories. To experience personally what inspirations running could bring to life, the author chose running as a total novice. From the initial physical and mental anguish, struggle and through continual adaptation, training and retrospection, the author gradually discovered the fun of running and the wide spectrum of emotions it generated - tranquility, flowing, soul-searching, torment, bondage, contradiction…etc. These voices enriched and changed the life of the author in a subtle way. The author was also able to discern life’s philosophies in the process. In the lapse of time, the author reviewed his own life story back and forth, and shared the story of runner Ahdar. He re-discovered himself, re-acquainted with himself, and realized that he still held many dreams and that running was a goal he could achieve. The temple of marathon is a symbol. Stepping into this temple is as if breaking through the cocoon in a rebirth, during which pain is a part of the experience. The pain suffered during training for marathon helps accumulate the strength to face future challenges. A person who has completed the pilgrimage of marathon will be likely to gain greater strength to realize other dreams in life.
Key words: Running, Runner, Life story
About Quaternary prevention in Public health ; comment on Dr Jong-Myon Bae paper
No full textpeer reviewedThe recent paper of Dr Jong-Myon Bae about Quaternary Prevention and Public Health in your journal has attracted my interest. The spread of this concept is beyond all expectation and I am quite happy it contributes to the analytic thinking of complexity of health care.
The particular application of the quaternary prevention (P4) concept is absolutely brilliant. Nevertheless I would propose some slight modifications to the table 1 edited by the author which I have taken the liberty to reproduce here with the due authorization of Dr Bae and after several mail exchanges with him
Moderate alcohol intake reduces risk of ischemic stroke in Korea : Author Response
No full textThe conclusion of the study by Lee et al.1 should be limited to about 60% of Koreans with normal acetaldehyde-metabolizing capacity from intact aldehyde dehydrogenase 2 (ALDH2). The nondrinker reference group appeared to be largely different from those of similar Western studies, potentially more prone to stroke, likely suggesting overestimation of beneficial effect by moderate alcohol intake.N
Various histone purification and in vitro chromatin reconstitution for the study of biophysical properties with magnetic tweezers assay
No full textDepartment of Biological SciencesEukaryotic DNA has a compacted high-ordered structure, known as chromatin. The fundamental units of chromatin are nucleosomes, which consist of DNA and histone proteins. Chromatin structure has many biological functions. For instance, chromatin protects DNA from damaging factors. DNA metabolism such as transcription and DNA repair is also regulated by chromatin structure. In addition, histone tail regions are targets for post-translational modification, which is associated with epigenetic control of DNA metabolism. In this paper, I purified all canonical Xenopus laevis core histone proteins in E. coli system with a milligram scale. Histone octamer was well assembled with dialysis and purified as size exclusion in vitro condition. Then, a single nucleosome was successfully reconstituted in vitro. Nucleosome reconstitution was confirmed with electrophoretic shift assay and micrococcal nuclease assay. Multiple nucleosomes were also reconstituted with multiple Widom 601 sequences, which have high binding affinity to histone octamer, in vitro. To investigate the tail effect on nucleosome stability, histones, in which tail region is deleted, were generated using mutagenesis. The tailless histone was overexpressed in E. coli system and purified using size exclusion and ion-exchange chromatographic techniques, successively. Purified tailless histones can be still reconstituted into nucleosomes. Magnetic tweezers technique is one of the single molecule techniques to characterize the physical properties of DNA molecules. The multiple-nucleosome formation was confirmed using magnetic tweezers. With the method of this paper, in vitro multiple tailless nucleosomes will be able to reconstitute. In this case, it will be the key to histone tail effects research in vitro with magnetic tweezers. The undisclosed mechanism of some histone chaperones can be revealed with in vitro chromatin reconstitution and single molecule techniques.ope
High photosensitive sol-gel hybrid materials for direct photo-imprinting of micro-optics
No full textSol- gel derived inorganic- organic hybrid materials ( HYBRIMERs) were found to have high photosensitivity arising from large changes in refractive index and volume upon exposure to light. These materials combined different photosensitive mechanisms due to the presence of polymers and silica in the HYBRIMER structure. Photo- induced densification of a germanium- doped HYBRIMER gave an increase in refractive index accompanying a volume contraction. A methacrylate HYBRIMER was decomposed by long UV illumination, giving a low refractive index and resulting in a reduction in film thickness. Also, photo- initiators were locked inside the methacrylate HYBRIMER during illumination, giving a simultaneous increase in the refractive index and film thickness. Direct photo- imprinting using the photosensitive HYBRIMER was demonstrated for simple fabrication of gratings, microlens, and waveguides using a photomask, a phase mask, an interferometer, and laser writing.The author gratefully acknowledges the financial support
of the Sol-Gel Innovation Project (SOLIP) funded
by Ministry of Commerce, Industry, and Energy
(MOCIE) in Kore
Effects of Exhaust Throttling on Engine Performance and Residual Gas in an SI Engine
No full textThe author would like to thank CERC (Combustion Engineering Research Center), KAIST for the financial support
Fast Saccadic Eye Movements Contribute to the Worsened Postural Sway in Older Adults Who Have Experienced Falls
No full textope
Innovation strategy of local pharmaceutical firms in Korea: a multivariate analysis
No full textThis article examines 37 local pharmaceutical firms in Korea to identify different patterns of innovation behaviour associated with four types of firms, which are categorized by two variables: the scale of operation and technological capability. Both bivariate and multivariate analyses support the hypotheses that these four types of firms exhibit different innovation strategies and in turn the level of performance they achieved. There are also fragmented indications that many local firms have long evolved from small firms with low capability to large firms with high capability. Finally, managerial and theoretical implications for the innovation strategies in LDCs/NICs are discussed. -from Author
- …
