4,794 research outputs found

    sj-docx-1-msj-10.1177_13524585221080667 – Supplemental material for The expansion and severity of chronic MS lesions follows a periventricular gradient

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    Supplemental material, sj-docx-1-msj-10.1177_13524585221080667 for The expansion and severity of chronic MS lesions follows a periventricular gradient by Samuel Klistorner, Michael H Barnett, Stuart L Graham, Chenyu Wang and Alexander Klistorner in Multiple Sclerosis Journal</p

    Redemption in the work of Francis Stuart

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    The idea of redemption is central to an understanding of the work of Francis Stuart. Through an examination of its development and expression, it is possible to demonstrate the integrity of his work and its distinctive qualities. Such a demonstration is necessary because Stuart's writing has been subjected to comparatively little scholarly inquiry, although reviews of his work, especially that produced since 1949, suggest that it is impressive and important. First, a general background to Stuart's work, a discussion of the special problems associated with reading it, and a summary of his corpus is provided. This indicates that the idea of redemption is important to his earliest writing. The state of redemption is shown to be a necessary apotheosis for Stuart's outcast heroes; it involves spiritual suffering through which may be found a sense of reintegration and a higher reality. This is expressed through interrelated themes such as those of gambler, artist and ordinary man; mystic and criminal; sacred and profane love; and spirituality and the mundane. The nature of the redemptive experience is further elaborated by distinctive, complex motifs, especially the hare, the ark and the woman-Christ. Their recurrence provides an important element in the unity of Stuart's work. Because Stuart's idea of the outcast raises important biographical questions, an examination of the relationship between Stuart's life and his work is made. Finally, the way in which the idea of redemption exists in the language structures of Stuart's novels is examined, with especial reference to his most recent work, The High Consistory. The thesis shows that the development of the these of redemption demonstrates the integrity of Stuart's work

    sj-docx-1-msj-10.1177_13524585211033464 – Supplemental material for Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter

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    Supplemental material, sj-docx-1-msj-10.1177_13524585211033464 for Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter by Samuel Klistorner, Michael H Barnett, Con Yiannikas, Joshua Barton, John Parratt, Yuyi You, Stuart L Graham and Alexander Klistorner in Multiple Sclerosis Journal</p

    High polygenic risk is associated with earlier treatment initiation and escalation in glaucoma suspects

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    Abstract #A0360Henry Marshall, Xikun Han, Sean Mullany, Georgie Hollitt, Ella Claire Berry, Lachlan Knight, Richard A Mills, John Landers, Paul Healey, Alex W Hewitt, Stuart L Graham, Robert Casson, Stuart MacGregor, Owen Siggs, Jamie E Crai

    119 loci influencing intraocular pressure provide new insight into primary open angle glaucoma susceptibility and age of onset

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    Abstract #1177Jamie E. Craig, Alex W. Hewitt, David Mackey, Stuart L Graham, Paul R Healey, Andrew JR White, John Landers, Robert Casson, Emmanuelle Souzeau, Kathryn P Burdon, Puya Gharahkhani, Stuart MacGrego

    A glaucoma polygenic risk score strongly associated with disease prediction and treatment intensity

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    This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.Jamie E Craig; Ayub Qassim; Xikun Han; Mark Hassall; Robert James Casson; Stuart L Graham; David A Mackey; Colin Willoughby; Kathryn P Burdon; John Landers; Emmanuelle Souzeau; Janey L Wiggs; Alex W Hewitt; Stuart MacGrego

    A polygenic risk score predicts functional progression in early primary open-angle glaucoma

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    Abstract #A0353Owen Siggs, Ayub Qassim, Xikun Han, Henry Marshall, Sean Mullany, Emmanuelle Souzeau, Anna Galanopoulos, Ashish Agar, John Landers, Robert Casson, Alex W Hewitt, Paul Healey, Stuart L Graham, Stuart MacGregor, Jamie Crai

    The APOE E4 allele is associated with faster rates of mGCIPL thinning in the PROGRESSA cohort

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    Abstract #A0153Sean Mullany, Henry Marshall, Emmanuelle Souzeau, Mark Hassall, Ashish Agar, Anna Galanopoulos, John Landers, Paul Mitchell, Paul Healey, Stuart L Graham, Alex W Hewitt, Stuart MacGregor, Puya Gharahkhani, Robert Casson, Owen Siggs, Jamie E Crai

    Sleep Apnoea Syndrome Correlated with Progression of Normal Tension Glaucoma

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    Ella Claire Berry, Henry Marshall, Mark Hassall, Antonia Kolovos, Joshua Schmidt, Sean Mullany, Stewart Lake, Anna Galanopoulos, John Landers, Paul Healey, Stuart L Graham, Alex W Hewitt, Stuart MacGregor, Robert Casson, Owen Siggs, Jamie E Crai

    The Life and Letters of the Lady Arbella Stuart

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    Lady Arbella Stuart, a woman nearly forgotten in history and literature and yet a woman who lived a full and exciting life which is well documented in her letters to her family, friends and royalty (both Queen Elizabeth I and James VI and I). Arbella Stuart was born in 1575 to Elizabeth Cavendish and Charles Darnley and was brought up by her maternal grandmother, Bess of Hardwick. She was educated from birth about her proximity to the throne (there was a chance she could have been queen when Elizabeth died) and the important role she had in life. There have been several biographies written about Stuart over the years and most recently an excellent text of her existing letters by Sara Jayne Steen which is the primary source of information for this thesis. This thesis examines Stuart’s tone, rhetoric and style in a selection of letters written over the course of her life, where possible using manuscripts viewed in the British Library and Hardwick Hall, as well as the published text. Part of what makes Stuart such an interesting subject is her ability to manipulate her reader and assume different personae, depending on whom she was writing to. The young Stuart writes passionately and often without thinking first, putting her thoughts on paper and then quickly sending them off to the Queen and her advisers. An older and wiser Stuart writes from James VI and I’s court and is very formal in her letters to the King. She is more relaxed when writing to her Aunt and Uncle and depicts court life in a lively informal fashion giving us a valuable insight into what life as a courtier would have been like at this time. Finally the thesis examines Stuart’s last letters written from imprisonment, the work of a desperate woman, fighting for her freedom. Stuart, like most of us, had a multi-faceted personality. She was at times an apparently submissive and subservient subject of the King; a well read and educated woman who adopted the guise of humility and deference to those in authority, the patriarchal order in place. This thesis will depict the many different sides to Stuart and give a brief overview of her exciting and turbulent life, told through her letters
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