121,920 research outputs found
Paul Raabe et Barbara Strutz, Lessings Bucherwerbungen. Verzeichnis der in der herzoglicher Bibliothek Wolfenbiittel angeschafften Biicher und Zeitschriften 1770-1781, 2004
No full textBourel Dominique. Paul Raabe et Barbara Strutz, Lessings Bucherwerbungen. Verzeichnis der in der herzoglicher Bibliothek Wolfenbiittel angeschafften Biicher und Zeitschriften 1770-1781, 2004. In: Dix-huitième Siècle, n°37, 2005. Politiques et cultures des Lumières. p. 718
A desensitization-inhibiting mutation in the glutamate binding site of rat alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is dominant in heteromultimeric complexes
No full textA desensitization-inhibiting mutation in the glutamate binding site of AMPA receptor subunits is dominant in heteromultimeric complexes
No full textPaul Raabe et Barbara Strutz, Lessings Bucherwerbungen. Verzeichnis der in der herzoglicher Bibliothek Wolfenbiittel angeschafften Biicher und Zeitschriften 1770-1781, 2004
No full textBourel Dominique. Paul Raabe et Barbara Strutz, Lessings Bucherwerbungen. Verzeichnis der in der herzoglicher Bibliothek Wolfenbiittel angeschafften Biicher und Zeitschriften 1770-1781, 2004. In: Dix-huitième Siècle, n°37, 2005. Politiques et cultures des Lumières. p. 718
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
No full textAbstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
No full textTubulointerstitial fibrosis is a hallmark feature of chronic renal injury. Specific therapies to control the progression of renal fibrosis toward end-stage renal failure are limited. Previous studies have demonstrated that expression of endogenous bone morphogenic protein-7 (BMP-7) is reduced in the kidneys of several inducible mouse models of acute and chronic renal disease and that administration of exogenous recombinant human BMP-7 (rhBMP-7) has a beneficial effect on kidney function. Here we report that treatment with rhBMP-7 leads to improved renal function, histology, and survival in mice deficient in the alpha(3)-chain of type IV collagen and MRL/MpJ(lpr/lpr) lupus mice, two genetic models for chronic renal injury and fibrosis. Such therapeutic benefit is also associated with a significant decrease in the expression of profibrotic molecules, such as type I collagen and fibronectin, in renal fibroblasts. Additionally, rhBMP-7 induces expression of active matrix metalloproteinase-2, which is potentially important for removal of fibrotic matrix. Collectively, these studies provide further evidence for rhBMP-7 as an important bone-associated protein with protective function against renal pathology.NIDDK NIH HHS [DK 51711, DK 55001
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