1,721,074 research outputs found
Pain and work: a short review
No full textIntroduction Pain and work are related in a number of ways. This brief review aims to provide an introduction, by means of illustrative examples from the literature, to four aspects of pain and work that are relevant to those involved with managing pain: work causing pain, pain interfering with work, the impact of pain treatment on work-related outcomes and interventions for the treatment and prevention of pain that can be performed at the workplace. Discussion It is well known that damage to the musculoskeletal apparatus as it may occur during occupational accidents or as a result of occupational diseases may lead to chronic painful states. Psychological factors at the job may also have an impact on pain perception. Painful conditions, including those due to musculoskeletal pain, lead to substantial loss of time at work and productivity. Conclusion It is perhaps less well known that work-related outcomes may inform about treatment success, also in the context of clinical trials, and that they may be of use in validating the responder outcomes that are now often used in pain trials. The evidence base for workplace-related interventions for preventing and treating painful conditions is weak
Pain and work: a short review
No full textIntroduction Pain and work are related in a number of ways. This brief review aims to provide an introduction, by means of illustrative examples from the literature, to four aspects of pain and work that are relevant to those involved with managing pain: work causing pain, pain interfering with work, the impact of pain treatment on work-related outcomes and interventions for the treatment and prevention of pain that can be performed at the workplace. Discussion It is well known that damage to the musculoskeletal apparatus as it may occur during occupational accidents or as a result of occupational diseases may lead to chronic painful states. Psychological factors at the job may also have an impact on pain perception. Painful conditions, including those due to musculoskeletal pain, lead to substantial loss of time at work and productivity. Conclusion It is perhaps less well known that work-related outcomes may inform about treatment success, also in the context of clinical trials, and that they may be of use in validating the responder outcomes that are now often used in pain trials. The evidence base for workplace-related interventions for preventing and treating painful conditions is weak
A systematic review identifies shortcomings in the reporting of crossover trials in chronic painful conditions
No full textObjectives: To investigate the reporting of study features of interest in abstracts and full texts of journal publications of crossover trials in chronic painful conditions. Study Design and Setting: Systematic review based on a MEDLINE (PubMed) search (January 1990-August 2014). Results: Ninety-eight publications on crossover studies with 3,513 study participants were eligible for inclusion. Double-blind status and randomized allocation to treatment groups are commonly reported in both abstracts and full texts (90 of 98 publications and 82 of 98 publications, respectively). Adverse events are reported in both abstract and full text in 49 of 98 publications and in the full text only in 44 of 98. A breakdown of results by treatment period is provided only in 23 of 98 publications, and if so, is reported only in the full text, never in the abstract. There is a time trend for the reporting of randomization in abstracts; it is more likely to be reported in recent studies (P = 0.0094). No time trends are detected in the reporting of double-blind status (P = 0.1087) and adverse events (P = 0.6084). Conclusion: The reporting of adverse events in the abstract and the reporting of results specified by crossover period in the full texts of journal publications on crossover pain trials should be improved. (C) 2015 Published by Elsevier Inc.Daiichi Sankyo, Inc
Comment on: Implications of latency period between benzene exposure and development of leukemia-A synopsis of literature
No full textUsing the internet in the management of multiple sclerosis: an overview of the evidence available
No full textUsing the internet in the management of multiple sclerosis: an overview of the evidence available
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