177 research outputs found
Capacity and traffic safety analysis of two crossings at the strada Nuova per Opicina (SR58), municipality of Trieste, Opicina
No full textV sklopu diplomske naloge smo predstavili prometno varnostno in kapacitetno analizo dveh križišč, ki se nahajata v občini Trst, in sicer na območju deželne ceste (SR58) Nova cesta za Opčine/(SR58) Strada Nuova per Opicina, in dveh stranskih cest, ceste za Ferluge/Salita a Conconello in Ulice Della Bellavista. V prvem delu diplomske naloge smo predstavili varnostno analizo s pomočjo programov Microsoft Access in ArcMap, s katerima smo tudi grafično prikazali vse lokacije nezgod. S pomočjo urada za infrastrukturo, logistiko in transportne storitve Avtonomne Dežele Furlanije Julijske Krajine in tržaške občinske policije smo na analiziranem odseku zbrali podatke 10 letnih nezgod, in sicer od leta 2010 do 2019. V nadaljevanju so navedene in opisane rešitve, ki bi zmanjšale cestne nesreče.
V drugem delu diplomske naloge smo predstavili kapacitetno analizo obravnavanih križišč. Izvedli smo analizo obstoječega in planskega stanja, ki ga predvidevamo čez 20 let. Ugotovili smo, da je današnji nivo uslug nezadosten glede na sodobni pravilnik. Zato smo zasnovali nove rešitve, s katerimi bi izboljšali prometni tok na odseku. S programom SIDRA INTERSECTION 9 smo izdelali variante obstoječega stanja in ga primerjali z dvemi variantami (križišči s sistemom semaforizacije in krožno križišče). Na podlagi rezulatov lahko sklepamo najboljšo rešitev: krožno križišče.My graduation thesis focuses on the safety and traffic analysis of two intersections, located in the municipality of Trieste, namely in the area where the regional road Strada nuova per Opicina intersects with the roads Salita a Conconello and Via della Bellavista.
The first part of the examines the safety of the area. The safety analysis was conducted by using the programs Microsoft Access and ArcMap, to graphically display all the locations where the accidents occurred. The collaboration with the Office for Infrastructure, Logistics and Transport Services of the Region Friuli Venezia Giulia and the municipal police made possible the collection of information regarding the annual accidents from 2010 to 2019. The results based upon the collected data confirmed the presence of critical points, where the numbers of road accidents peaked. In the final part of the research possible solutions to reduce road accidents are presented.
The second part of the thesis consists in the analysis of the traffic load during the peak hours. The current load of traffic was the starting point for the research. Statistical tools and calculations were applied to the current data in order to show the traffic conditions in the next 20 years. The results reveal how the road intersections are characterized by heavy traffic and therefore, are not flow. The latter part of the analysis shows some potential solutions to the problem. In this case, the program SIDRA INTERSECTION 9 was used. Models of the area were created both reproducing the current and the future state of the intersections. The two models were compared with a solution where a traffic light system and a roundabout were installed. The final results indicate how the best solution to diminish the traffic congestion and increase the safety is the creation of a roundabout
The cytotoxic effect of slow Loris (nycticebus) venom, on human cancer cells
No full textWithin the Kingdom Mammalia, venom evolution is rare, occurring in only six orders. Arguably the most cryptic, and academically neglected venom occurs within primates among slow lorises (Nycticebus spp.). Venoms comprise novel biological compounds with a potential plethora of proteins and peptides available for utilisation in bio-medical research. We collected samples of slow loris saliva from eight captive-bred pygmy slow lorises (N. pygmaeus) at Paignton Zoo and Shaldon Wildlife Trust UK, given voluntarily as slow lorises chewed on Salimetrics children’s swabs. From January to March 2017, we employed MTT assays, and microscopy assessments to determine cell survival on human epidermal carcinoma cells (A431 line) after the application of concentrations of slow loris salivary venom. Cell survival from both male and female derived saliva was half that of untreated cells. Cytotoxic action is demonstrated in concentrations as low as 0.01% venom. Results demonstrate a cytotoxic effect with ensuing physiological damage on human cancer cells, demonstrating the cytotoxic action of slow loris saliva only, without the admixture of brachial gland exudate. We show that even captive-bred slow loris saliva harbours potentially dangerous substances, with functional applications towards slow loris husbandry. Knowledge of slow loris salivary venom increases understanding of the novel salivary composition and supports discussions of slow loris conservation by proposing a functional narrative to oppose the illegal pet trade, by contradicting their ‘cute and cuddly’ appeal. Evidence of salivary venom shows that cytotoxic effects can result even in the absence of a bite puncturing the skin, and further demonstrates their inappropriateness as pets
Iscrizione nei libri contabili obbligatori e circolazione dei debiti aziendali (con alcune considerazioni sui criteri di imputazione e di responsabilità tra diritto civile e diritto commerciale)
No full textThe author, inspired by a recent jurisprudential conflict emerged in the judgments passed by the Italian Supreme Court about the legal interpretation of the section 2560, paragraph 2 c.c. (which states the assumption of the company debts), examines the most important and recent Italian theories about the legal framework of the company and shows how the different solutions to the issue are dictated by a different concept of the subjective imputation criteria and the liability for breach of contract
The sticky tasty: the nutritional content of the exudativorous diet of the Javan slow loris in a lowland forest
No full textPlant exudates are an important food source for many primates. The Critically Endangered Javan slow loris (Nycticebus javanicus) was previously found to prefer Acacia decurrens exudate in an anthropogenically disturbed site, while its feeding habits in secondary natural forest remain unknown. Knowledge of the chemical characteristics of the plant exudates that Javan slow lorises consume is limited, especially with respect to those that they feed on in natural forests. As plant exudates may contain plant secondary metabolites (PSM), which are considered unpalatable in high concentrations, differences in PSM composition may drive feeding preferences. This research aims firstly to confirm exudate consumption by the Javan slow loris in a lowland tropical forest in Central Java, and secondly to identify the chemical characteristics of the exudates consumed. We followed wild slow lorises in Kemuning Forest, Central Java and observed their behaviour. We investigated the gum-producing trees that were utilized by the slow lorises by tapping the exudates and examining their nutritional and PSM contents. We found that exudates are the predominant food source for the Javan slow loris in this lowland forest, and that their nutritional contents are similar to those of exudates consumed by lorises in anthropogenically disturbed areas. Significant differences in polysaccharide and flavonoid contents were found between consumed and unconsumed exudates. Knowledge of the diet of the Javan slow loris is crucial to its conservation, and our findings confirm the importance of exudates in its diet. We also highlight the need to preserve natural slow loris habitat, and to manage the diets of these species in captivity. The results of this study indicate that plant exudates should constitute a significant portion of the diet of captive slow lorises, and that the presence of exudate-producing trees is vital in areas into which slow lorises are to be translocated. © 2021, The Author(s), under exclusive licence to Japan Monkey Centre
Development of cooperation of 9th grade students in the biology topic of "How a new organism is created?
No full textSadarbības pilnveidošana 9. klases skolēniem bioloģijas tematā "Kā rodas jauns organisms?". Autors: Gustavs Loris. Darba vadītāja: Vad. pētn. Dr. paed. Rita Birziņa. Diplomdarbs, 42 lappuses, 5 attēli, 4 tabulas, 29 literatūras avoti, 9 pielikumi. Latviešu valodā. Darba mērķis ir noskaidrot, vai ar strukturētu pieeju 9. klases skolēni bioloģijas tematā "Kā rodas jauns organisms?" uzrādīs augstāku akadēmisko sniegumu un sadarbības prasmes grupu darbā. Darba metodes veido pedagoģiskais novērojums, kritērijos balstīts akadēmiskā snieguma vērtējums un aptauja. Ir secināts, ka uzdevumā ar sadarbību noteicošiem elementiem, konkrētām darba lomām skolēni uzrāda augstāku akadēmisko sniegumu un labākas sadarbības prasmes darba izstrādē, kā arī skolēniem ir augstāka skaidrība un atbildība par savu veicamo uzdevumu. Būtiskus izaicinājumus sagādā nepietiekamas sadarbībai pakārtotās prasmes, galvenokārt, komunikācijas prasmes, kuras ir attīstāmas ilgākā laika posmā.Development of cooperation of 9th grade students in the biology topic of "How a new organism is created?". Author: Gustavs Loris. Supervisor: Sen. res. Dr. paed. Rita Birziņa. Diploma thesis, 42 pages, 5 figures, 4 tables, 29 references, 9 attachments. In Latvian. Aim of this thesis is to find out, whether with structured approach 9th grade students will show higher academic achievement and cooperation skills in group work in the biology topic of "How a new organism is created?". Methods comprise pedagogic observation, academic achievement assessment based in criteria, and a survey. It is concluded that in a group task with cooperation promoting elements students show higher academic achievement and better cooperation skills during work, also the students have greater clarity and responsibility in their specific task. Significant challenges are posed by insufficient cooperation subordinate skills, as communication skills, which are to be developed in a longer period of time
Mechanical significance of femoral head trabecular bone structure in Loris and Galago evaluated using micromechanical finite element models
No full textWork on the interspecific and intraspecific variation of trabecular bone in the proximal femur of primates demonstrates important architectural variation between animals with different locomotor behaviors. This variation is thought to be related to the processes of bone adaptation whereby bone structure is optimized to the mechanical environment. Micromechanical finite element models were created for the proximal femur of the leaping Galago senegalensis and the climbing and quadrupedal Loris tardigradus by converting bone voxels from high-resolution X-ray computed tomography scans of the femoral head to eight-noded brick elements. The resulting models had approximately 1.8 million elements each. Loading conditions representing takeoff phase of a leap and more generalized load orientations were applied to the models, and the models were solved using the iterative row-by-row matrix-vector multiplication algorithm. The principal strain and Von Mises stress results for the leaping model were similar for both species at each load orientation. Similar hip joint reaction forces in the range of 4.9 × to 12 × body weight were calculated for both species under each loading condition, but the hip reaction values estimated for Loris were higher than predicted based on locomotor behavior. These results suggest that functional adaptation to hip joint loading may not fully explain the differences in femoral head trabecular bone structure in Galago and Loris. The finite element method represents a unique and useful tool for analyzing the functional adaptation of trabecular bone in a diversity of animals and for reconstructing locomotor behavior in extinct taxa. Am J Phys Anthropol, 2004. © 2004 Wiley-Liss, Inc
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Direct Ink Write Strain Sensors for Continuum Robotics
No full textThe growing field of soft and continuum robotics requires new types of strain sensors that are stretchable, flexible, and can function at much higher strains than traditional strain gauges can handle. Sensors made of three different stretchable conductive materials (silver-polymer composite, carbon-polymer composite, and liquid metal composite) were printed using direct ink write onto stretchable thermoplastic polyurethane films. The response of the sensors was evaluated over a period of cyclic stretching under different strain, speed, and dwell conditions, and evaluated in terms of gauge factor, linearity, and drift. The results show that the silver-based sensor material has high drift, a gauge factor of between 1.75 and 21.06, and a linearity of between 82.4% and 99.63%. The carbon-based material has a slightly negative drift, a linearity of between 96.71% and 98.51%, and a gauge factor of between 1.65 and 3.69. The liquid metal-based material has low drift, a linearity of 99.8%, and a gauge factor of between 0.75 and 1.03. Based on these results, the printed liquid metal-based sensor was chosen for integration with two continuum robots, namely a 3D-printed concentric agonist-antagonist robot (CAAR) and a metal shape memory alloy notched wrist tube (NWT), by adhering the sensor onto the robot bodies. The printed liquid metal-based sensor showed good performance in tracking the motion of both types of robots. The endurance of the sensor for the CAAR was limited by the sensor detaching from the material due to the low temperature of lamination of the sensor onto the robot body, originating from the temperature limitation of the 3D printed CAAR material. The performance of the sensor for the NWT showed excellent motion tracking over the entire tested range. This work has shown that the sensor is easily manufacturable and that the digital design can be adjusted to fit a wide range of soft robots. The understanding of the behavior of the sensor over a range of conditions and an extended period of use allows a soft robot’s movement to be accurately tracked by the printed strain sensor
Experimental Investigation on a Beam-Column Node of a Multi-Story Precast RC System
No full textThe results of an experimental program, devoted to the investigation of the structural behaviour of a precast RC beam-column node under cyclic loading, are described. The experimental activity is part of a research campaign developed to evaluate the seismic behaviour of a multi-story precast concrete system completed in situ. The experimental tests have been carried out by imposing cyclic quasi-static transverse displacements at the two end sections of the beams. An axial load on the column is also applied, simulating the vertical load given by the permanent actions. The seismic performance of the node is experimentally studied. The hysteresis response and the strain profiles of the steel bars (longitudinal reinforcement and stirrups) within the node are recorded. The ductility of the connection and the cyclic strength degradation at prescribed displacement values are also evaluated
La Pedagogía de Loris Malaguzzi.: Por una "nueva" idea de infancia
No full textL’articolo illustra gli elementi essenziali che contraddistinguono il pensiero di Loris Malaguzzi inquadrando il contributo di questo Autore nell’ambito della recente storia della pedagogia dell’infanzia italiana con particolare riferimento alle realtà dell’asilo nido e della scuola dell’infanzia. In particolare, nell’articolo si delineeranno gli elementi di novità che hanno modificato in modo permanente il nostro modo d’intendere l’infanzia (e la sua educazione) soprattutto a partire dagli apporti delle teorie costruttiviste, da Piaget fino a Vygotskij, Bruner e Gardner. Da questa analisi emerge il profilo culturale di un Autore ricco e complesso, che ha saputo innovare la didattica per l’infanzia attraverso una pluralità di prospettive: da quella metodologica a quella politica, da quella della gestione degli spazi educativi fino agli orizzonti dell’educazione estetica, della creatività e della valorizzazione del gioco simbolico.
Da questa analisi ne emerge il volto di un innovatore geniale e produttivo, capace di intrecciare i linguaggi dell’educazione con quelli della cultura, del sapere tecnico con quello umanistico, senza divaricazioni, e con uno sguardo sempre attento a cogliere le potenzialità dell’infanzia, in chiave attuale e futura, immaginando così il volto di un nuovo bambino, più adeguato ad un mondo in transizione e in movimento.The article illustrates the essential elements that distinguish the thought of Loris Malaguzzi framing the contribution of this Author within the recent history of the Early Childhood Education and Care in Italy with particular reference to the pre-school sector. In particular, the contribution will outline the elements of novelty that have permanently changed the way we understand childhood (and its education), especially from the contributions of constructivist theories (Piaget Vygotskij, Bruner, Gardner). From this analysis the cultural profile of a rich and complex Author stands out, who has been able to innovate teaching for children through a plurality of perspectives: from methodological to political, from the management of educational spaces to the horizons of aesthetic education, creativity and the enhancement of symbolic play.
From this analysis emerges the face of a brilliant and productive innovator, able to intertwine the languages of education with those of culture, of technical knowledge with the humanistic one, in a unitary perspective, and with an always careful look to grasp the potential of childhood, in a current and future key, thus imagining the face of a new child, more appropriate to a world in transition and movement.El artículo ilustra los elementos esenciales que distinguen el pensamiento de Loris Malaguzzi enmarcándolo en el contexto de la historia reciente de la pedagogía infantil italiana con especial referencia al sector preescolar. En particular, la contribución describirá los elementos novedosos que han cambiado permanentemente nuestra forma de entender la infancia (y su educación), especialmente a partir de los aportes de las teorías constructivistas (Piaget Vygotskij, Bruner, Gardner). De este análisis emerge el perfil cultural de un autor rico y complejo, que ha sido capaz de innovar la enseñanza para niños a través de una pluralidad de perspectivas: de metodológica a política, desde la gestión de espacios educativos hasta los horizontes de la educación. estética, de la creatividad y de la valorización del juego simbólico.
De este análisis surge el rostro de un innovador brillante y productivo, capaz de entrelazar las lenguas de la educación con las de la cultura, del conocimiento técnico con el humanístico, en una perspectiva unitaria, y con una mirada siempre cuidadosa para captar el potencial de la infancia, en clave actual y futura, imaginando así el rostro de un nuevo niño, más apropiado para un mundo en transición y movimiento
Insights into Probiotic Prescription among Gastroenterologists and Other Healthcare Professionals: Evidence from an Italian Survey
No full textBackground: Probiotics, which are live microorganisms that provide health benefits, have been extensively studied for their various clinical applications. However, despite their potential, high-quality data supporting their use in several gastrointestinal diseases are often lacking, and prescription behaviors can widely differ. This study aimed to assess different behaviors in probiotics knowledge and prescriptions among Italian gastroenterologists and healthcare professionals (HPs). Methods: A web-based electronic survey was distributed to all participants at the National Meeting of the Italian Young Gastroenterologist and Endoscopist Association (AGGEI) held in 2023. The survey investigated probiotic prescription practices for several gastrointestinal conditions, such as acute diarrhea, irritable bowel syndrome, inflammatory bowel disease, and diverticular disease. Results: Among 200 participants, 142 completed the survey, of whom 59 were gastroenterologists and 83 were HPs (surgeons, nutrition biologists, and other physicians). Significant differences were observed in the prescription of probiotics for the treatment of acute diarrhea and H. pylori. Both groups prescribed probiotics in monthly cycles for patients with IBS, although the majority prescribed multistrain formulations. Gastroenterologists were more likely to prescribe cyclic courses for IBS, while HPs tended to continue therapy by changing the probiotic strain in case of inefficacy. For ulcerative colitis, gastroenterologists prescribed probiotics more but for shorter durations. In Crohn’s disease, gastroenterologists prescribed probiotics less and were less likely to prescribe multistrain formulations. Regarding SUDD, gastroenterologists tended to prescribe probiotics less frequently, although without a significant difference, with similar rates of preference for multistrain formulations. Conclusions: This survey highlights heterogeneous behaviors in probiotic prescription between gastroenterologists and HPs, with gastroenterologists more aligned with guidelines and available scientific evidence. Hence, enhancing probiotic education among healthcare professionals and gastroenterologists is crucial. Further studies are needed to better understand probiotics’ role in gastrointestinal disorders through large-scale randomized controlled trials
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