5,721 research outputs found

    Lifecourse social position and D-dimer; findings from the 1958 British birth cohort

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    The aim is to examine the association of lifecourse socioeconomic position (SEP) on circulating levels of D-dimer. Data from the 1958 British birth cohort were used, social class was determined at three stages of respondents' life: at birth, at 23 and at 42 years. A cumulative indicator score of SEP (CIS) was calculated ranging from 0 (always in the highest social class) to 9 (always in the lowest social class). In men and women, associations were observed between CIS and D-dimer (P<0.05). Thus, the respondents in more disadvantaged social classes had elevated levels of D-dimer compared to respondents in less disadvantaged social class. In multivariate analyses, the association of disadvantaged social position with D-dimer was largely explained by fibrinogen, C-reactive protein and von Willebrand Factor in women, and additionally by smoking, alcohol consumption and physical activity in men. Socioeconomic circumstances across the lifecourse at various stages also contribute independently to raised levels of D-dimer in middle age in women only. Risk exposure related to SEP accumulates across life and contributes to raised levels of D-dimer. The association of haemostatic markers and social differences in health may be mediated by inflammatory and other markers

    Surface studies of the interaction of cesium with feldspars

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    PT: J; CR: ABRY DRM, 1982, TR189 ADAMS I, 1972, EARTH PLANET SC LETT, V16, P429 BARNEY GS, 1975, ARHSA218 ATL RICHF H BARRER RM, 1963, J CHEM SOC, P434 BERNER RA, 1979, GEOCHIM COSMOCHIM AC, V43, P1173 BOULTON J, 1978, AECL6314 GOODWIN BW, 1981, P NEA WORKSHOP OECD, P33 HAINES RI, UNPUB KOMARNENI S, 1978, INORG NUCL CHEM LETT, V14, P173 STRACHAN DM, 1977, ARHSA294 ATL RICHF H THOMAS S, 1973, J VAC SCI TECHNOL, V10, P218 TORSTENFELT B, 1981, 429 PROGR RAD AVF RE; NR: 12; TC: 2; J9: ACS SYMP SER; PG: 11; GA: SG601Source type: Electronic(1

    Rayleigh number dependence of the Archimedes number dependent large-scale flow structure formation in mixed convection

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    We report on experimental investigations of large-scale flow structure formation in mixed convection. We characterize the flow field by measuring the velocity fields within a rectangular model room using 2D2C PIV. The control parameters are the Reynolds number Re, the Rayleigh number Ra and the Prandtl number Pr. All parameters are linked through the Archimedes number Ar. In 6.4x10-2 ≤ Ar ≤ 1.39x101, 4.2x103 ≤ Re ≤ 6.35x104 and Ra = 3.1x107, Ra = 1.8x108 and Pr = 0.713 we found flow 3 different flow structures. While keeping Ra and Pr constant and varying Ar through Re variations, we found an Ar dependence of the largescale flow structure formation within 6.4x10-2 ≤ Ar ≤ 1.39x101. Furthermore, we found a Ra dependence of the structure formation, which shifts the transition points between the structures to higher Archimedes numbers and reduces the mean velocities within the investigated domain

    Reynolds numbers near the ultimate state of turbulent Rayleigh-Bénard convection

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    We report on measurements of the mean-flow Reynolds number ReU and the rms fluctuation Reynolds number ReV in turbulent Rayleigh-Bénard convection as a function of the Rayleigh number Ra for 4 x 1011 < Ra < 2 1014 and Pr ' 0:8. Both can be described by the same power law with an effective exponent = 0:44, in agreement with predictions for ReU but in disagreement with predictions for ReV

    Logarithmic variance profiles and the corresponding f-1 spectra of temperature fluctuations in turbulent Rayleigh-Bénard convection

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    We report experimental results for the temperature variance 2(z) and the corresponding frequency spectra P(f) in turbulent Rayleigh-Bénard convection (RBC) in a cylindrical sample of aspect ratioT= D/L = 1:00 (D = 1:12 m is the diameter and L = 1:12 m the height). The measurements were conducted in the Rayleigh-number range 1011 < Ra < 1:35 1014 and Pr ' 0:8. For Ra = 1:35x1014, 2(z) could be described well by a logarithmic dependence on the vertical position z in a range of z 1 < z < z 2 with z 1 ' 70 and z 2 = 0:1L. Here L=(2Nu) is the thickness of a thin thermal sublayer adjacent to the horizontal plate where the heat flux (denoted by the Nusselt number Nu) is carried mostly by thermal diffusion. In the log layer, we found that the temperature spectra had a significant frequency range over which P(f) f with close to 1. As Ra decreased, increased so that the log layer became thinner. At Ra = 2:05 1011, z 2 < z 1 and therefore there was no range for a log layer. Correspondingly, the temperature spectrum near the horizontal plate did not have the f1 scaling form either

    Lagrangian Raylaigh-Bénard convection

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    Using passive tracers as sensors, we obtain Lagrangian measurements of tracers position, velocity and temperature in Rayleigh-Bénard convection at Ra=10^7-10^9. We report on statistics of temperature, velocity, and heat transport (Nusselt number). We observe that the Nusselt number is characterized by a largely intermittent behavior, likely due to the interaction of temperature with turbulent velocity fluctuations

    Intergenerational 20 year trends in the prevalence of asthma and hay fever in adults: the Midspan family study surveys of parents and offspring

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    &lt;b&gt;Objective&lt;/b&gt;: To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. Design: Two epidemiological surveys 20 years apart. Identical questions were asked about asthma, hay fever, and respiratory symptoms at each survey. Setting: Renfrew and Paisley, two towns in the west of Scotland. &lt;b&gt;Subjects&lt;/b&gt;: 1477 married couples aged 45-64 participated in a general population survey in 1972-6; and 2338 offspring aged 30-59 participated in a 1996 survey. Prevalences were compared in 1708 parents and 1124 offspring aged 45-54. &lt;b&gt;Main outcome measures&lt;/b&gt;: Prevalences of asthma, hay fever, and respiratory symptoms. Results: In never smokers, age and sex standardised prevalences of asthma and hay fever were 3.0% and 5.8% respectively in 1972-6, and 8.2% and 19.9% in 1996. In ever smokers, the corresponding values were 1.6% and 5.4% in 1972-6 and 5.3% and 15.5% in 1996. In both generations, the prevalence of asthma was higher in those who reported hay fever (atopic asthma). In never smokers, reports of wheeze not labelled as asthma were about 10 times more common in 1972-6 than in 1996. With a broader definition of asthma (asthma and/or wheeze), to minimise diagnostic bias, the overall prevalence of asthma changed little. However, diagnostic bias mainly affected non-atopic asthma. Atopic asthma increased more than twofold (prevalence ratio 2.52 (95% confidence interval 1.01 to 6.28)) whereas the prevalence of non-atopic asthma did not change (1.00 (0.53 to 1.90)). &lt;b&gt;Conclusion&lt;/b&gt;: The prevalence of asthma in adults has increased more than twofold in 20 years, largely in association with trends in atopy, as measured indirectly by the prevalence of hay fever. No evidence was found for an increase in diagnostic awareness being responsible for the trend in atopic asthma, but increased awareness may account for trends in non-atopic asthma

    Photochemical behavior of some p-styryistilbenes and related compounds: Spectral properties and photoisomerization in solution and in solid state

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    Author Posting. © The Authors (2006) This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in PHOTOCHEMISTRY AND PHOTOBIOLOGY, 82(6): 1645-1650. https://doi.org/10.1562/2006-01-17-RA-780ArticlePhotochemistry and Photobiology. 82(6): 1645-1650 (2006)journal articl

    Aspect-ratio dependence of the transition to the ultimate state of turbulent Rayleigh-Bénard convection

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    We report on measurements of the ultimate-state transition in turbulent Rayleigh-B\'enard convection obtained in a large facility known as the ``Uboot of G\"ottingen" and using pressurized sulfur hexafluoride as the convecting fluid. We found that the transition occurs over a range of RaRa which becomes more narrow as Γ\Gamma increases, ranging from Ra1Ra_1^* which is at most weakly dependent on Γ\Gamma and close to 101310^{13} to Ra2Ra_2^* which varies from about 2×10152\times 10^{15} for Γ=0.33\Gamma = 0.33 to about 7×10137\times 10^{13} for Γ=1.00\Gamma = 1.00

    Wall to wall optimal transport

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    The calculus of variations is employed to find steady divergence-free velocity fields that maximize transport of a tracer between two parallel walls held at fixed concentration for one of two constraints on flow strength: a fixed value of the kinetic energy or a fixed value of the enstrophy (the mean square rate of strain in this situation). The optimizing flows realize upper limits on convective transport in this scenario. We interpret the results in the context of buoyancy-driven Rayleigh–Bénard convection problems that satisfy the flow intensity constraints, enabling us to investigate how optimal transport scalings compare with upper bounds on Nu expressed as a function of the Rayleigh number Ra
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