34 research outputs found
Our sorrows
No full textTitle: Тъгите ни (Our sorrows) Originally published: Almanac Южни цветове, 1907, pp. 62–111. Language: Bulgarian The excerpts used are from the anthology: Stoyan Iliev ed., Блуждаеща естетика. Българските символисти за символизма, (Sofia: Издателство на БАН, 1992), pp. 158–161. About the author Dimo Kyorchev [1884, Veliko Tarnovo – 1928, Paris]: philosopher, essayist and politician. His father Petar Kyorchev was a teacher and former collaborator of Vasil Levski, the leader of the movement for..
Our sorrows
No full textTitle: Тъгите ни (Our sorrows) Originally published: Almanac Южни цветове, 1907, pp. 62–111. Language: Bulgarian The excerpts used are from the anthology: Stoyan Iliev ed., Блуждаеща естетика. Българските символисти за символизма, (Sofia: Издателство на БАН, 1992), pp. 158–161. About the author Dimo Kyorchev [1884, Veliko Tarnovo – 1928, Paris]: philosopher, essayist and politician. His father Petar Kyorchev was a teacher and former collaborator of Vasil Levski, the leader of the movement for..
The Reflective Entrepreneur
Get PDFIn a world where entrepreneurial success often seems deceptively accessible, it is not always clear what makes a person entrepreneurial. In this book, Dimo Dimov offers a reflective insight into the entrepreneurial journey, striking up a conversation about entrepreneurship in order to challenge and untangle existing preconceptions. A discussion of challenges and tensions such as idea versus opportunity, genius versus lunatic, and skill versus luck forms the foundation of the book, while the second part offers actions and considerations which can help the reader to seek opportunities in a fractious environment. The final part of the text focuses on the collective spirit in entrepreneurship, arising from the interplay between participation and outcomes. The author brings a succinct diversity to the field, making this book essential reading for undergraduate and postgraduate students on entrepreneurship courses, as well as scholars, researchers, and practitioners looking for a new perspective on entrepreneurship
The Reflective Entrepreneur
Get PDFIn a world where entrepreneurial success often seems deceptively accessible, it is not always clear what makes a person entrepreneurial. In this book, Dimo Dimov offers a reflective insight into the entrepreneurial journey, striking up a conversation about entrepreneurship in order to challenge and untangle existing preconceptions. A discussion of challenges and tensions such as idea versus opportunity, genius versus lunatic, and skill versus luck forms the foundation of the book, while the second part offers actions and considerations which can help the reader to seek opportunities in a fractious environment. The final part of the text focuses on the collective spirit in entrepreneurship, arising from the interplay between participation and outcomes. The author brings a succinct diversity to the field, making this book essential reading for undergraduate and postgraduate students on entrepreneurship courses, as well as scholars, researchers, and practitioners looking for a new perspective on entrepreneurship
The Role of Transcription Factor Zbtb20 in the Development of Interneurons in the Neocortex of Mice // Роля на транскрипционен фактор Zbtb20 в развитието на интерневрони в крайномозъчна кора на мишка
No full textИнтерневроните са нервни клетки, които използват гама-аминомаслена киселина (ГАМК) като невротрансмитер. Ембрионално произлизат от герминативна зона в теленцефалона, наречена субпалиум. От там мигрират тангенциално докато достигнат палиума на теленцефалона.
Процесите на неврогенеза и миграция са под строг генетичен контрол, който е област на усилено проучване. Голям брой от молекулярните фактори в тази регулаторна верига са вече известни. Нашата хипотеза е че транскрипционният фактор Zbtb20 участва в генетичния контрол на ембрионалното развитие на CINs. Неговата роля във формирането на глутаматергичните неврони на неокортекса беше вече публикувана от група ни, благодарение на вече генериран глобален хомозиготен Zbtb20-/- “knock-out” мутант. Докладвани са също така и дефекти в развитието на хипокампа и олфакторния булб при липса на Zbtb20.
Нищо не се знае негово участие в неврогенезата на интерневроните. По наши предварителни данни Zbtb20 има силна експресия в субпалиума, зоната където интерневроните нормално се образуват. За да проучим детайлно въздействието на Zbtb20 върху интерневроногенезата, ние ще изследваме мозъчни тъкани от трансгенни мишки с инактивация на гена, кодиращ Zbtb20.
При хора, мутации в гена са свързани с разстройства на нервното развитие. Делеция в гена за Zbtb20 води до синдрома на Primrose, който се характеризира със поведенчески нарушения, симптоми от аутистичния спектър, калцификация на региони в мозъка, макроцефалия, умствени нарушения др.Interneurons are nerve cells that use gamma-aminobutyric acid (GABA) as a neurotransmitter. They arise embryonically from a germinal zone in the telencephalon called the subpallium. From there, they migrate tangentially until they reach the pallium of the telencephalon.
The processes of neurogenesis and migration are under tight genetic control, which is an area of intense research. A large number of the molecular factors in this regulatory chain are already known. Our hypothesis is that the transcription factor Zbtb20 is involved in the genetic control of the embryonic development of CINs. Its role in the formation of glutamatergic neurons of the neocortex was already published by our group, thanks to an already generated global homozygous Zbtb20-/- “knock-out” mutant. Defects in hippocampal and olfactory bulb development in the absence of Zbtb20 have also been reported.
Nothing is known about its involvement in the neurogenesis of interneurons. According to our preliminary data, Zbtb20 has strong expression in the subpallium, the area where interneurons normally form. To study in detail the impact of Zbtb20 on interneuronogenesis, we will examine brain tissues from transgenic mice with inactivation of the gene encoding Zbtb20.
In humans, mutations in the gene are associated with neurodevelopmental disorders. A deletion in the Zbtb20 gene leads to Primrose syndrome, characterized by behavioural disorders, autism spectrum symptoms, calcification of brain regions, macrocephaly, mental disorders, etc
A rare variation of superior rectus muscle
No full textThe extraocular muscles are responsible for all eye movements required to track and fix objects. Superior rectus muscle is located in the superior level of the orbital cavity, below musculus levator palpebrae superioris, tilted slightly to the lateral part of the orbit. In a routine dissection, we found a left, unilateral variation of the superior rectus muscle with no variation in other structures, such as nerves and vessels. The abnormal muscle presented in two parts - medial and lateral ones. The medial part bifurcated into two heads with different insertion points. It is a case of a rare variation of the extraocular muscles, which, to our knowledge, has not yet been reported
Optimal μ-Distributions for the Hypervolume Indicator for Problems With Linear Bi-Objective Fronts: Exact and Exhaustive Results
Get PDFcorrected author versionInternational audienceTo simultaneously optimize multiple objective functions, several evolutionary multiobjective optimization (EMO) algorithms have been proposed. Nowadays, often set quality indicators are used when comparing the performance of those algorithms or when selecting ``good'' solutions during the algorithm run. Hence, characterizing the solution sets that maximize a certain indicator is crucial---complying with the optimization goal of many indicator-based EMO algorithms. If these optimal solution sets are upper bounded in size, e.g., by the population size μ, we call them optimal μ-distributions. Recently, optimal μ-distributions for the well-known hypervolume indicator have been theoretically analyzed, in particular, for bi-objective problems with a linear Pareto front. Although the exact optimal μ-distributions have been characterized in this case, not all possible choices of the hypervolume's reference point have been investigated. In this paper, we revisit the previous results and rigorously characterize the optimal μ-distributions also for all other reference point choices. In this sense, our characterization is now exhaustive as the result holds for any linear Pareto front and for any choice of the reference point and the optimal μ-distributions turn out to be always unique in those cases. We also prove a tight lower bound (depending on μ) such that choosing the reference point above this bound ensures the extremes of the Pareto front to be always included in optimal μ-distributions
МЕТОДИКА ЗА БАЛАНСВИ ОПИТИ ЗА ГЪСКИ, ОБМЕННА ЕНЕРГИЯ И ИСТИНСКА СМИЛАЕМОСТ НА АМИНОКИСЕЛИНИТЕ НА ОСНОВНИ ФУРАЖНИ КОМПОНЕНТИ ПРИ ТЯХНОТО ХРАНЕНЕ
Get PDFA review of the methods for balanced experiments for establishing of the metabolizable energy and the amino acids digestibility for waterfowl has been made. Systemizing the former experience in this fi eld, the author submits some innovations, regarding to the adaptation of the methods for experiments with geese. The results for metabolizable energy and true digestibility coeffi cients of some basic for the feeding of geese forages (established using the adapted
methods) are given. A using of specifi ed for the different birds data for the nutritive values of the forages has been recommended. The offered innovations could be used for further efforts for establishing of standardizing methods for balanced experiments with waterfowl.Направен е обзор на методите за балансови опити за установяване на обменната енергия и смилаемостта на аминокиселините при водоплаващи птици. Систематизирайки досегашният опит в тази област, авторът е предложил нововъведения, отнасящи се до адаптирането на методиката за опити с гъски. Дадени са и резултатите за обменната енергия и смилаемостта на аминокиселините на някои основни при храненето на гъски фуражи, получени от проведени по адаптираната методика опити. Препоръчва се ползването на данни за хранителната стойност на фуражите, специфични за различните видове птици. Предлаганите нововъведения
могат да послужат като основа за по- нататъшни усилия за определяне на стандартизирана методика за балансови опити с водоплаващи птици
An indigenous tattoo artist in the 21st century : approaching and re-exposing ancestral MUISCA symbology (culture) through tattooing.
No full textEste estudio explora el tatuaje como una herramienta artística y educativa para revitalizar la identidad muisca en la sociedad contemporánea. A partir de un análisis auto etnográfico, el autor conecta su historia personal con su herencia. Línea gráfica Neo-Muisca basada en símbolos ancestrales.
El trabajo surge como respuesta a la pérdida de identidad indígena en contextos urbanos y la falta de representación de la cultura muisca en el arte del tatuaje, dominado por estilos extranjeros. Como solución, plantea la creación de un “Manual de Tatuaje Neo-Muisca” con símbolos ancestrales adaptados al arte corporal moderno. También analiza la historia del tatuaje, la relación del cuerpo con la identidad y la importancia de la reapropiación cultural.
Más que una expresión estética, el tatuaje es concebido como un acto de resistencia y reapropiación cultura como un acto de resistencia y reapropiación cultural, permitiendo reconectar con sus raíces indígenas.Licenciado en Artes VisualesPregradoThis study explores tattooing as an artistic and educational tool to revitalize the Muisca identity in contemporary society. Based on an auto-ethnographic analysis, the author connects his personal history with his heritage. Neo-Muisca graphic line based on ancestral symbols.
The work arises as a response to the loss of indigenous identity in urban contexts and the lack of representation of the Muisca culture in tattoo art, dominated by foreign styles. As a solution, it proposes the creation of a “Neo-Muisca Tattoo Manual” with ancestral symbols adapted to modern body art. It also analyzes the history of tattooing, the relationship of the body with identity and the importance of cultural reappropriation.
More than an aesthetic expression, tattooing is conceived as an act of resistance and cultural reappropriation, allowing one to reconnect with their indigenous roots.Pedagogías de lo artístico visua
