8,883 research outputs found

    Jahrbuch des S.A.C / 25 Silvretta-Linard-Gruppe : vom Pischahorn (2983 m) aus

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    gezeichnet (Sommer 1889) v. M. Stocker, Ing. (Sect. Gotthard S.A.C.) ; Lith. R. Armbruster, BernFederlithographieFussleiste, rechts: Jahrbuch d. S.A.C. Bd. XX

    Jahrbuch des S.A.C / 25 Silvretta-Linard-Gruppe : vom Pischahorn (2983 m) aus

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    gezeichnet (Sommer 1889) v. M. Stocker, Ing. (Sect. Gotthard S.A.C.) ; Lith. R. Armbruster, BernFederlithographieFussleiste, rechts: Jahrbuch d. S.A.C. Bd. XX

    Enseñanza de la escritura de Max Aub: comprensión y memoria

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    Este texto analiza a obra testimonial de Max Aub sobre su experiencia en los campos de concentración en Francia desde una perspectiva de discursos comparados. Para destacar las estrategias de la escritura del autor recuperables por otros proyectos discursivos que persigan la sensibilización y la denuncia a través del cruce entre la comunicación y la éticaThis text analyses the testimonial work of Max Aub about his experience in the French concentration camps in France from comparative discourses approach. It emphasizes the writing strategies used by the author useful for other awareness and denounce discourses through the dialogue among communication and ethic

    Max Brooks literary reading flier

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    2012 Bismarck State College Visiting Writers Series and ArtsQuest present: Max Brooks. April 25, 7:30 p.m.; Belle Mehus Auditorium. Max Brooks is the author of World War Z: An Oral History of the Zombie War and the graphic novel The Zombie Survival Guide: Recorded Attacks

    Max Frisch's novel: Stiller. A study

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    The attempt is made in the following study to present an interpretation of the novel "Stiller" by the Swiss author, Max Frisch, by tracing through the novel the dominant themes of the graven-image or 'Bildnis' and that of the problem of freedom with reference to the novel's main character. ThesisMaster of Arts (MA

    A Transfer Report on the Development of a Framework to Evaluate Search Interfaces for their Support of Different User Types and Search Tactics

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    As the understanding of search systems, user needs and seeking strategies is developing, the design of search user interfaces is evolving to support more complicated and exploratory forms of search. With the design of new search features that enable these richer modes of exploration, comes the need to better understand the support they provide. In this report a new evaluation framework is presented that analyses search features for how they a) contribute to an overall interface, b) allow users to carry out different search tactics, and c) support different types of users and their needs. The novel contributions of the framework improve on some of the limitations of typical user studies, and allow search systems to be systematically analysed in much more detail and in much less time. The presented evaluation framework is then validated in three ways. First the validity of the models used as the building blocks of the framework are investigated through related work. Second the method of integrating these building-block models is validated and strengthened by consensus of expert opinion. Third, the overall approach is validated by comparing its analyses to the results of previously carried out user studies. The validation process has shown both the value of the framework and identified areas of future work that should be addressed for the framework to be completed. This report concludes with the set of contributions that the framework makes, and why the remaining work will be challenging, but critical to the final design

    Developmental Regulation of Small-Conductance Ca²⁺-Activated K⁺ Channel Expression and Function in Rat Purkinje Neurons

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    Calcium transients play an important role in the early and later phases of differentiation and maturation of single neurons and neuronal networks. Small-conductance calcium-activated potassium channels of the SK type modulate membrane excitability and are important determinants of the firing properties of central neurons. Increases in the intracellular calcium concentration activate SK channels, leading to a hyperpolarization of the membrane potential, which in turn reduces the calcium inflow into the cell. This feedback mechanism is ideally suited to regulate the spatiotemporal occurrence of calcium transients. However, the role of SK channels in neuronal development has not been addressed so far. We have concentrated on the ontogenesis and function of SK channels in the developing rat cerebellum, focusing particularly on Purkinje neurons. Electrophysiological recordings combined with specific pharmacological tools have revealed for the first time the presence of an afterhyperpolarizing current (I_{AHP}) in immature Purkinje cells in rat cerebellar slices. The channel subunits underlying this current were identified as SK2 and localized by in situ hybridization and subunit-specific antibodies. Their expression level was shown to be high at birth and subsequently to decline during the first 3 weeks of postnatal life, both at the mRNA and protein levels. This developmental regulation was tightly correlated with the expression of I_{AHP} and the prominent role of SK2 channels in shaping the spontaneous firing pattern in young, but not in adult, Purkinje neurons. These results provide the first evidence of the developmental regulation and function of SK channels in central neurons

    Was ist bloss mit Max Muster los? - Psychische Probleme in Kleinunternehmen

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    Psychische Probleme und die Auswirkungen am Arbeitsplatz - drei eindrückliche Beispiele, drei Schicksale, drei Lösungen

    The subzero microbiome: Microbial activity in frozen and thawing soils

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    Most of the Earth's biosphere is characterized by low temperatures (<5 °C) and cold-adapted microorganisms are widespread. These psychrophiles have evolved a complex range of adaptations of all cellular constituents to counteract the potentially deleterious effects of low kinetic energy environments and the freezing of water. Microbial life continues into the subzero temperature range, and this activity contributes to carbon and nitrogen flux in and out of ecosystems, ultimately affecting global processes. Microbial responses to climate warming and in particular, thawing of frozen soils are not yet well understood although the threat of microbial contribution to positive feedback of carbon flux is substantial. To date, several studies have examined microbial community dynamics in frozen soils and permafrost due to changing environmental conditions, and some have undertaken the complicated task of characterizing microbial functional groups and how their activity changes with changing conditions, either in situ or by isolating and characterizing macromolecules. With increasing temperature and wetter conditions microbial activity of key microbes and subsequent efflux of greenhouse gases also increase. In this review, we aim to provide an overview of microbial activity in seasonally frozen soils and permafrost. With a more detailed understanding of the microbiological activities in these vulnerable soil ecosystems, we can begin to predict and model future expectations for carbon release and climate change.Peer reviewe

    Frontline Timor : to resist is to win. by Max Stahl

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    tag=1 data=Frontline Timor : to resist is to win. by Max Stahl tag=2 data=Stahl, Max tag=3 data=The Australian Magazine, tag=6 data=18/19 January 1992 tag=7 data=6-12. tag=8 data=SOUTH-EAST ASIA tag=9 data=EAST TIMOR tag=10 data=The author describes a rarely permitted visit to the secret camps of the Timorese guerillas who, despite the Dili massacre and the crushing presence of the Indonesian military, continue to hold out and plot for independence. tag=11 data=1992/4/2 tag=12 data=92/0116 tag=13 data=CABThe author describes a rarely permitted visit to the secret camps of the Timorese guerillas who, despite the Dili massacre and the crushing presence of the Indonesian military, continue to hold out and plot for independence
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