263 research outputs found
Glioblastoma /
No full textClinically focused and designed to provide a to-the-point overview, Glioblastoma, by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care.Includes bibliographical references.Glioblastoma: translating scientific advances to innovative therapy -- The story of glioblastoma: history and modern correlates -- Epidemiology of glioblastoma and trends in glioblastoma survivorship -- The molecular pathogenesis of glioblastoma -- Translating molecular biomarkers of gliomas to clinical practice -- Multimodality targeting of glioma cells -- Current standards of care in glioblastoma therapy -- Radiographic detection and advanced imaging of glioblastoma -- Principles and tenets of radiation treatment in glioblastoma -- Chemotherapeutics and their efficacy -- Antiangiogenic therapy for glioblastoma -- Recurrent glioblastoma -- Principles of surgical treatment -- Awake craniotomy for glioblastoma -- Intraoperative imaging of glioblastoma -- Minimally invasive targeted therapy for glioblastoma: laser interstitial thermal therapy -- Local drug delivery in the treatment of glioblastoma -- Tumor-treating electric fields for glioblastoma -- Brain plasticity and reorganization before, during, and after glioma resection -- General principles of immunotherapy for glioblastoma -- Early detection of glioblastoma -- Health-related quality of life and neurocognitive functioning after glioblastoma treatment -- Socioeconomics and survival -- National and global economic impact of glioblastoma -- Lessons learned : clinical trials and other interventions for glioblastoma.Clinically focused and designed to provide a to-the-point overview, Glioblastoma, by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care.Elsevie
Method of rapidly visualizing essential neural pathways
No full textA method of optimizing pre-operative procedures in the field of neurosurgery. The method facilitates the identification of essential fiber tract pathways that must be avoided when planning and performing an operation, thereby increasing surgical safety and avoiding complications. The method includes the combined use of four variables in Diffusion Tensor Imaging (DTI)-Fiber Tracking (FT) of projection fibers in the brain. These variables include Jain-Brem™ fractional anisotropy constant for tractography (JB-FACT), Jain-Brem™ fiber length (JB-FL), subcentimeter size placement of regions of interest (ROI), and the placement of ROIs to cover the anatomical pathway of projection fibers. JB-FACT and JB-FL provide rapid, reproducible tracking for projection fibers in the brain
Supplementary_Figure_1_(2) - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Figure_1_(2) for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Table_2_(1) - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Table_2_(1) for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Table_3 - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Table_3 for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Figure_5 - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Figure_5 for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Figure_3_(1) - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Figure_3_(1) for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Figure_2_(3) - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Figure_2_(3) for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Table_4 - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Table_4 for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
Supplementary_Figure_4_(2) - Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma
No full textSupplementary_Figure_4_(2) for Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah, Zev A. Binder, Derek A. Oldridge, Jianhua Zhao, David B. Lieberman, Jacquelyn J. Roth, Christopher D. Watt, Shrey Sukhadia, Eva Klinman, Robert D. Daber, Arati Desai, Steven Brem, Donald M. O’Rourke and Jennifer J. D. Morrissette in Academic Pathology</p
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