162,821 research outputs found
2023 Hollister Lecture
Mr. Stepien graduated from Elmhurst College in 1965 and began his career as a middle school social studies teacher. In 1978, he became a program developer and senior author for the K-7 social studies series for the Scott, Foresman Company. When IMSA opened in 1985, he was tapped to plan curriculum, hire faculty, and help with facility design. Joining its faculty, he taught at IMSA for ten years. In 1994, Mr. Stepien became IMSA’s director of the Center for Problem-Based Learning, turning his full attention to research and writing about applications of PBL in elementary and secondary schools. He established the Consortium for Problem-Based Learning at Northern Illinois University in 1997 and became a national consultant in PBL for the Association for Supervision and Curriculum Development (ASCD). Mr. Stepien consulted with more than fifty schools every year, presented at numerous national meetings and conventions, and consulted with organizations such NASA, the Museum of Science and Industry (Chicago), Prime Time School Television, and The Wall Street Journal
[Report to Chief J. E. Curry, by an unknown author #1]
Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
[Report to Chief J. E. Curry, by an unknown author #2]
Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
New Obesity Indices and Adipokines in Normotensive Patients and Patients With Hypertension: Comparative Pilot Analysis.
We compared the obesity parameters and selected adipokines—leptin, adiponectin, and resistin—in obese patients with
hypertension and normotensive patients. A total of 67 nondiabetic obese outpatients were divided into 2 groups: A–hypertensive
and B–normotensive. Serum levels of leptin, adiponectin, resistin, and insulin were measured.Weight, height, waist circumference,
and hip circumference were measured to calculate waist-to-hip ratio (WHR), weight-to-height ratio, visceral adiposity index, and
body adiposity index (BAI). Among patients with hypertension, significant positive correlations were observed between leptin
and body mass index and BAI (r = .31 and r = .63, respectively). In normotensive patients, leptin positively correlated with BAI
(r = .73, P < .01) and negatively with WHR (r = -.55, P < .0001); adiponectin negatively correlated with WHR (r = .38, P < .01)
and BAI (r = .52; P < .0001), and resistin negatively correlated with WHR (r = -.36, P < .05). In conclusion, visceral obesity and
leptin are associated with hypertension in obese patients
Meal inertia: the impact of eating different sized meals on vigilant attention throughout the night
Abstract #0171Gupta CC, Dorrian J, Centofanti S, Coates A, Kennaway D, Wittert G, Heilbronn L, Catcheside P, Noakes M, Stepien J, Chandrakumar D, Coro D, Banks
Predictors of insulin resistance in patients with obesity: a pilot study.
We compared adipokines and inflammatory markers in obese insulin-sensitive (group A, n 1⁄4 16) and insulin-resistant (group B,
n 1⁄4 48) patients divided according to homeostasis model assessment of insulin resistance (HOMA-IR). Serum levels of
adiponectin, leptin, resistin, high-sensitivity C-reactive protein, interleukin 6, and tumor necrosis factor a were measured.
Weight, height, waist (WC) and hip circumferences, waist to hip ratio , weight to height ratio, visceral adiposity index (VAI), and
body adiposity index (BAI) were measured. The WC and VAI were significantly higher in group B (113.9 + 11.1 vs
105.3 + 9.8cm; P < .01 and 2.3 + 1.1 vs 1.6 + 0.9; P < .05, respectively), while serum adiponectin levels were higher in group
A (24.5 + 14.6 vs 15.1 + 9.6 ng/mL; P < .005). The BAI strongly correlated with adiponectin and leptin in group B (r = .479;
P < .001 and r = .705; P < .001). Insulin resistance is associated with visceral adiposity described by VAI and WC. The BAI may
be a useful index in obese patients, especially with insulin resistance
Biomass gasification and syngas production for use in solid oxide fuel cell: gas cleaning and conditioning, and performance tests
Performance tests with a SOFC unitfuelled with syngas produced from biomass gasification ractors, properly conditioned and cleaned
Murder on the mountain: author talk with Peter J. Wosh
Author talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.
Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes
Neoplastic transformation was found to have a marked effect on the expression of nuclear DNA (nDNA)- and mitochondrial DNA (mtDNA)-encoded oxidative phosphorylation (OXPHOS) genes. Examining three pairs of human diploid fibroblasts and their SV 40-transformed counterparts revealed that mRNAs for the nuclear-encoded ATP synthase beta and the adenine nucleotide translocator (ANT) isoform 1 and 2 genes were markedly induced, whereas the mRNA for the ANT isoform 3 gene remained unchanged. The mRNA levels for the mtDNA-encoded 12 S rRNA, ND2, ATPase6+8, COIII, ND5+6, and Cytb genes were also increased, whereas the mtDNA number declined. Similar analysis of a cervical carcinoma (HeLa), fibrosarcoma (HT1080), and an Epstein-Barr virus (EBV)-transformed lymphoblastoid line (EBV-L) revealed that all three ANT isoforms were also expressed in these cells. Hence, changes in the expression of OXPHOS genes may be a common feature of transformed cells
- …
