3,341 research outputs found
Stephen F. Austin.
No full textBrief biographical narratives about Ellis P. Bean and Stephen F. Austin
Christopher Maginn / Steven G. Ellis, The Tudor Discovery of Ireland
No full textAls im Jahr 1485 mit Heinrich VII. der erste Tudorkönig den englischen Thron bestieg, galt Irland als unbedeutendes, von gälischen Barbaren beherrschtes Randgebiet. Auf der politischen Agenda der jungen Dynastie gewann die Insel nur langsam an Bedeutung. Irland, so die zentrale Überlegung der beiden Autoren Christopher Maginn und Stephen G. Ellis, war also ein weißer Fleck auf der englischen Landkarte, der in der frühen Tudorzeit erst noch besucht, beschrieben und entdeckt werden musste. Belastbare Informationen wurden in London erst nach und nach verfügbar, zumeist auf der Grundlage schriftlicher Berichte und Traktate. Wie dieses Wissen über Irland gewonnen und in der höfischen Gesellschaft in politisches Kapital umgemünzt wurde, wollen Maginn und Ellis in ihrer 2015 erschienenen Untersuchung zeigen
Strategic approaches in coronary intervention, 3rd Ed./ Edit. : Stephen G. Ellis
No full textxiv, 546 hal. : ill.; 27 cm
Strategic approaches in coronary intervention, 3rd Ed./ Edit. : Stephen G. Ellis
No full textxiv, 546 hal. : ill.; 27 cm
Affect, Albert Ellis, and Rational-Emotive Therapy
No full textThe theme is advanced that affect is an integral component of the Rational-Emotive Therapy model. The affective aspect of the model is reviewed in terms of theoretical constructs and therapeutic techniques. Several references to author-observed interactions of Albert Ellis are made and the life-style of Albert Ellis is described to permit inferences regarding the role of affect.Le thème mis en avant dans cette étude est que le domaine affectif est une partie composante du modèle de la Thérapie Rationnelle-Emotive. L\u27auteur examine l\u27aspect affect if du modèle en ce qui concerne les concepts théoriques et les techniques thérapeutiques. Plusieurs références aux interactions d\u27Albert Ellis observées par l\u27auteur sont faites et la manière de vivre d\u27Albert Ellis est décrite afin de permettre des inferences concernant le rôle de l\u27affection
Ellis Island today: Located in the Upper Bay west of Jersey City and southwest of Manhattan
No full textEllis Island is a significant historical site just up the bay from tiny Liberty Island in Upper New York Bay. Why? Because it was here that millions of immigrants first put foot in America. But where is Ellis Island? Until recently, a coastal boundary dispute between New York and New Jersey made the answer to that question uncertain. The island was originally only 3 or so acres but because of the filling of tidal waters around the island to create room to house and process the immigrants, the island grew to over 27 acres. New Jersey claimed jurisdiction to all those areas filled but New York insisted the entire island, no matter what its size, was hers based on a compact signed by the two states in 1834. In 1980 the State of New Jersey Department of Environmental Protection (NJDEP), as part of the statewide effort to delineate tidelands delineated a claim line that essentially claimed the entire filled portion of Ellis Island, except the original three acres. (In New Jersey, all lands flowed by the tide now or formerly are owned by the state). New York objected. The states continued to squabble. Finally, in 1993, the State of New Jersey invoked the Supreme Courts jurisdiction to try the dispute. Coastal boundaries have historically been mapped on linen, and more recently mylar, but in this case the NJDEP invoked the modern technology of GIS to assist the state?s attorney general in preparing the case. Historic maps were scanned and registered to modern ortho-photography to assist in determining where and when areas were filled. GPS points were gathered and surveys made. All the digital data was then analyzed on the GIS to show where and how much fill was placed in the area. New Jersey used these data to argue that those areas filled after the compact were indeed still under the jurisdiction of New Jersey (Ellis Island is a National Park and therefore ownership was not the issue). A special master determined, and on May 26th 1998 the Supreme Court agreed, that New Jersey had sovereign authority over the filled land added to the original island. New York retained authority to the original 3-acre island. GIS was then used to implement the Supreme Court?s decision. NJDEP GIS scientists delineated the line between states using historical digital maps and adjusted the boundary line between states to the satisfaction of all parties. This paper will detail this historic decision and the implementation of the decision and the critical role GIS played.This is an updated version of the presentation entitled: GIS and Coastal Boundary Disputes: Where is Ellis Island? In this updated version, the author has added slides in order to better explain how the angles in the Fort Gibson wall, that was constructed just prior to the War of 1812, were used to align the 1857 survey of Ellis Island with current island.There is a companion paper to the 1999 version of this presentation. See: Professional Surveyor, July August 1999, Vol. 19, Number 6, pp 8-14.Purpose: Describes the delineation of the jurisdictional boundary between New Jersey and New York, on Ellis Island, as per the Supreme Court ruling of 1998. See: New Jersey v. New York, 523 U.S. 767 (1998)
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Session G: Nuclear Power/Climate Change – TerraPower’s Traveling Wave Reactor
No full textTyler Ellis is a project manager for TerraPower, where he works on developing and deploying new nuclear generating capacity to meet current and future energy needs. Before working at TerraPower, Ellis worked as a reactor supervisor at the Massachusetts Institute of Technology (MIT) Nuclear Reactor Laboratory and as a nuclear engineer for the MIT Center for Advanced Nuclear Energy Systems.
In 2007, Ellis worked with other MIT thought leaders to help shape the overall plan for the highly successful Bernard M. Gordon MIT Engineering Leadership Program. He composed plant design requirements for a high-temperature gas-cooled reactor with AREVA in France; conducted neutronic trade studies for three different nuclear electric propulsion systems at the Los Alamos National Laboratory; and explored economic, social and technical complexities in meeting the sustainability challenge in Switzerland.
Ellis earned both bachelors and master’s degrees in 2006 from the Massachusetts Institute of Technology in the field of nuclear science and engineering. In 2008, he earned his doctorate from MIT in the same field specializing in reactor physics. In addition, Ellis won several Best Technical Session awards for reactor physics at the American Nuclear Society student conferences. He was recognized by Scientific American as a Distinguished Scholar, received the American Nuclear Society John R. Lamarsh Memorial Award and was officially commended by the governor of California. In addition to having received several other awards, he is author/co-author of more than 15 publications and technical reports.TerraPower is moving forward with detailed plans for a sustainable, economic, and safe nuclear reactor. The Travelling Wave Reactor (TWR) – a reactor in the 500-megawatt electric range – uses unique core physics to initiate a breed and burn wave which can be completely sustained in fertile material. This process allows the TWR to convert depleted uranium waste into usable fuel as the reactor operates, providing a sustainable base-load power source. TerraPower is the first company to create a practical engineering embodiment of this previously studied concept thanks to a powerful advanced reactor modeling interface, developed in-house, which enables the analysis of traveling wave reactor technology in a way that has not been possible before. This presentation will provide more detail about the origins of the TWR, the project’s current status as well as some of the safety differences between TWRs and currently operating light water reactors
The effect of oxidation on the stability of G-quadruplex DNA : implications for oncogene expression
No full textG-quadruplexes (G4-DNA) are a class of secondary structures formed from Guanine rich sequences. In recent years these structures have been implicated in both telomere maintenance and oncogene expression, and have been shown to be abundant in upstream promoter regions and at telomeric ends.
The mutagenic properties of oxidative stress on DNA have been widely studied, as has the association with carcinogenesis. The oxidation of deoxyguanosine to 8-oxo-2’deoxyguanosine (8-oxo-dG) is the most common result when DNA is under oxidative stress and as such, the G-rich sequences that form G-quadruplexes can be viewed as potential “hot-spots” for DNA oxidation. We propose that oxidation may destabilise the G-quadruplex structure, leading to its unfolding into the duplex structure, affecting gene expression. This would imply a possible mechanism by which oxidation may impact on oncogene expression.
This project used both in silico and in vitro methods to observe the effect of oxidation on the G-quadruplex structure and the consequences in oncogene expression, using two biologically relevant G-quadruplex structures, those found in the promoter regions of the proto-oncogenes c-Myc and c-Kit as proof of concept.
Molecular dynamics (MD) simulations were performed (isothermic, isobaric 500ns unrestrained simulation in explicit solvent and counterions) on the c-Kit and c-Myc G-quadruplex structures with and without 8-oxo-dG incorporated into the central tetrad. FRET experiments were performed on these same structures, observing the conformation of sequences known to form G-quadruplexes under near physiological conditions and subjected to oxidative stress, through Fenton chemistry. Gene expression data analyses were also performed to evaluate the prevalence of different G-quadruplex forming motifs (GQMs) in genes affected by oxidation.Although no relevant information was gained from the FRET experiments, the MD results constitute the longest simulations of this type performed on the c-Myc and c-Kit G-quadruplex structures published to date and predict the high stability of these structures under normal physiological conditions. They also clearly demonstrate a destabilising effect of oxidation on G-quadruplex structures, with the extent of the effect dependent on the structure oxidised.
Furthermore, gene expression data analysis showed that genes whose expression is significantly altered when subjected to oxidative stress are statisticallymore likely to contain a GQM than the remainder of the genome, through the use of significance testing.
These findings demonstrate a differential effect of oxidation on G-quadruplexes, likely dependent on other known characteristics affecting G4 stability such as loop length and sequence. Results also point towards this mechanism affecting gene expression. This is suggestive of a novel route for oxidation mediated carcinogenesis, through upregulation of oncogene expression or possibly downregulation of tumour suppression genes
The mainstream primary classroom as a language-learning environment for children with severe and persistent language impairment - implications of recent language intervention research
No full textMany UK children with severe and persistent language impairment (SLI) attend local mainstream schools. Although this should provide an excellent language-learning environment, opportunities may be limited by difficulties in sustaining time-consuming, child-specific learning activities; restricted co-professional working, and the complex classroom environment. Two language intervention studies in mainstream Scottish primary schools showed children with SLI receiving intervention from speech and language therapists (SLTs) or their assistants made more progress in expressive language than similar children receiving intervention from education staff. Potential reasons for this difference are sought in the amount of tailored language-learning activity undertaken; how actively school staff initiated contact with SLTs; and the language demands of the classroom. Tailored language learning appears to be a differentiating factor. A language support model, reflecting views of teachers and SLTs about encouraging language development for children with SLI within the ecology of the mainstream primary classroom, is also outlined
Economic Impact of the Petroleum Industry on Ellis County, Kansas
No full textThis work is aimed at presenting to the reader ideas regarding the importance of the petroleum industry to Ellis County. While the findings and conclusions put forth may not give adequate answers to all questions relating to the various phases of the industry, they should give some explanation regarding the role that the industry plays in the economic development of the county. The introductory chapter gives the purposes for undertaking this work and describes the physical and economic characteristics of Ellis County. It also gives a brief description of the mining industry in the county. Chapter two is devoted to presenting a review of the history of the development of the oil industry in the county. In Chapter three, the emphasis is placed on explaining the method of input-output analysis. This method was utilized by the author in order to show the impact of the oil industry on the economy of Ellis County. The concluding chapter shows the impact on Ellis County of the decrease of oil production in a five-year period. In finishing this thesis the author reached the following conclusions: 1) The impact on the economy of Ellis County attributable to the decrease in the value of oil production of 3,202,500. B) The direct and indirect effects of the decrease in the value of oil production led to a 13,462,500. The total income to households decreased by 102. 2) In a region that is regarded as primarily agricultural, the petroleum production rather than the agricultural production has been the major source of income for Ellis County. But the reserves of oil are not inexhaustible; in fact, the production of oil in the county has been declining since the mid- 1950\u27s. Consequently, the income derived from this production has been declining. Thus, in order for the economy of the county to remain healthy and keep up with the national growth in the standard of living (per capita income,) it is very important that Ellis County undertakes constant planning in order to start or attract industries that will be able to more than fill the gap left by the decline in the oil industry
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