316 research outputs found
sj-docx-2-tag-10.1177_17562848221090834 – Supplemental material for Corticosteroid-free efficacy and safety outcomes in patients receiving tofacitinib in the OCTAVE Sustain maintenance study
No full textSupplemental material, sj-docx-2-tag-10.1177_17562848221090834 for Corticosteroid-free efficacy and safety outcomes in patients receiving tofacitinib in the OCTAVE Sustain maintenance study by Stephan R. Vavricka, Thomas Greuter, Benjamin L. Cohen, Walter Reinisch, Flavio Steinwurz, Marc Fellmann, Xiang Guo, Nervin Lawendy, Jerome Paulissen and Laurent Peyrin-Biroulet in Therapeutic Advances in Gastroenterology</p
sj-docx-1-tag-10.1177_17562848221090834 – Supplemental material for Corticosteroid-free efficacy and safety outcomes in patients receiving tofacitinib in the OCTAVE Sustain maintenance study
No full textSupplemental material, sj-docx-1-tag-10.1177_17562848221090834 for Corticosteroid-free efficacy and safety outcomes in patients receiving tofacitinib in the OCTAVE Sustain maintenance study by Stephan R. Vavricka, Thomas Greuter, Benjamin L. Cohen, Walter Reinisch, Flavio Steinwurz, Marc Fellmann, Xiang Guo, Nervin Lawendy, Jerome Paulissen and Laurent Peyrin-Biroulet in Therapeutic Advances in Gastroenterology</p
sj-docx-1-tag-10.1177_17562848231179335 – Supplemental material for Because I’m happy – positive affect and its predictive value for future disease activity in patients with inflammatory bowel diseases: a retrospective cohort study
No full textSupplemental material, sj-docx-1-tag-10.1177_17562848231179335 for Because I’m happy – positive affect and its predictive value for future disease activity in patients with inflammatory bowel diseases: a retrospective cohort study by Brian M. Lang, Martina Ledergerber, Sebastian Bruno Ulrich Jordi, Niklas Krupka, Luc Biedermann, Philipp Schreiner, Pascal Juillerat, Jacqueline Wyss, Stephan R. Vavricka, Jonas Zeitz, Roland von Känel, Gerhard Rogler, Niko Beerenwinkel and Benjamin Misselwitz in Therapeutic Advances in Gastroenterology</p
Supplemental Material1 - Supplemental material for Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease
No full textSupplemental material, Supplemental Material1 for Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease by Philipp Schreiner, Bahtiyar Yilmaz, Jean-Benoît Rossel, Yannick Franc, Benjamin Misselwitz, Michael Scharl, Jonas Zeitz, Pascal Frei, Thomas Greuter, Stephan R Vavricka, Valérie Pittet, Alexander Siebenhüner, Pascal Juillerat, Roland von Känel, Andrew J Macpherson, Gerhard Rogler, Luc Biedermann and on behalf of the Swiss IBD Cohort Study Group in United European Gastroenterology Journal</p
Supplemental Material2 - Supplemental material for Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease
No full textSupplemental material, Supplemental Material2 for Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease by Philipp Schreiner, Bahtiyar Yilmaz, Jean-Benoît Rossel, Yannick Franc, Benjamin Misselwitz, Michael Scharl, Jonas Zeitz, Pascal Frei, Thomas Greuter, Stephan R Vavricka, Valérie Pittet, Alexander Siebenhüner, Pascal Juillerat, Roland von Känel, Andrew J Macpherson, Gerhard Rogler, Luc Biedermann and on behalf of the Swiss IBD Cohort Study Group in United European Gastroenterology Journal</p
Supplemental Material3 - Supplemental material for Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease
No full textSupplemental material, Supplemental Material3 for Vegetarian or gluten-free diets in patients with inflammatory bowel disease are associated with lower psychological well-being and a different gut microbiota, but no beneficial effects on the course of the disease by Philipp Schreiner, Bahtiyar Yilmaz, Jean-Benoît Rossel, Yannick Franc, Benjamin Misselwitz, Michael Scharl, Jonas Zeitz, Pascal Frei, Thomas Greuter, Stephan R Vavricka, Valérie Pittet, Alexander Siebenhüner, Pascal Juillerat, Roland von Känel, Andrew J Macpherson, Gerhard Rogler, Luc Biedermann and on behalf of the Swiss IBD Cohort Study Group in United European Gastroenterology Journal</p
Therapies in Inflammatory Bowel Disease Patients with Extraintestinal Manifestations
No full textExtraintestinal manifestations (EIM) have become an important source of morbidity and disability as well as an identified risk factor for an unfavorably course of disease in inflammatory bowel diseases (IBD). Therefore, efforts have been put into a more global and interdisciplinary management of IBD patients in collaboration with rheumatologists, dermatologists, and ophthalmologists. A real therapeutic success has also been obtained with a more "systemic" IBD treatment associated with the development of monoclonal antibodies against TNF alpha and biological agents derived from the treatment of rheumatological disease (also called biological Disease-Modifying Antirheumatic Drugs). The prevalence of these EIM remains too low to undergo randomized controlled trials with this specific focus and therefore the evidence relies on case series and experts' opinions, which lowers the level of evidence. After a careful review of the most recent literature, this paper aims to update the reader on the latest therapeutic management of IBD patients with EIM
Perioperative dietary therapy in inflammatory bowel disease. Journal of Crohn and Colitis.
No full textAdamina M, Gerasimidis K, Sigall-Boneh R, Zmora O, de Buck van Overstraeten A, Campmans-Kuijpers M, Ellul P, Katsanos K, Kotze P, Noor N, Schäfli-Thurnherr J, Vavricka S, Wall C, Wierdsma N, Yassin N, Lomer M. (2019) jjz160
A shift from oral to intravenous iron supplementation therapy is observed over time in a large Swiss cohort of patients with inflammatory bowel disease
No full textBACKGROUND:: In 2007, leading international experts in the field of inflammatory bowel disease (IBD) recommended intravenous (IV) iron supplements over oral (PO) ones because of superior effectiveness and better tolerance. We aimed to determine the percentage of patients with IBD undergoing iron therapy and to assess the dynamics of iron prescription habits (IV versus PO). METHODS:: We analyzed anonymized data on patients with Crohn's disease and ulcerative colitis extracted from the Helsana database. Helsana is a Swiss health insurance company providing coverage for 18% of the Swiss population (1.2 million individuals). RESULTS:: In total, 629 patients with Crohn's disease (61% female) and 398 patients with ulcerative colitis (57% female) were identified; mean observation time was 31.8 months for Crohn's disease and 31.0 months for ulcerative colitis patients. Of all patients with IBD, 27.1% were prescribed iron (21.1% in males; 31.1% in females). Patients treated with steroids, immunomodulators, and/or anti-tumor necrosis factor drugs were more frequently treated with iron supplements when compared with those not treated with any medications (35.0% versus 20.9%, odds ratio, 1.94; P < 0.001). The frequency of IV iron prescriptions increased significantly from 2006 to 2009 for both genders (males: from 2.6% to 10.1%, odds ratio = 3.84, P < 0.001; females: from 5.3% to 12.1%, odds ratio = 2.26, P = 0.002), whereas the percentage of PO iron prescriptions did not change. CONCLUSIONS:: Twenty-seven percent of patients with IBD were treated with iron supplements. Iron supplements administered IV were prescribed more frequently over time. These prescription habits are consistent with the implementation of guidelines on the management of iron deficiency in IBD
Pregnancy and breastfeeding in inflammatory bowel disease
No full textInflammatory bowel disease (IBD) is frequent in women during their peak reproductive years. Accordingly, a significant number of questions and uncertainties arise from this population regarding the risk of transmission of IBD to the offspring, the impact of the disease and therapies on the fertility, the role of the disease on the course of the pregnancy and the mode of delivery, the impact of the therapy on the pregnancy and fetal development as well as breastfeeding. The safety of medical therapy during pregnancy and lactation is a major concern for both pregnant women and their partners as well as for physicians. As a general rule, it can be stated that the benefit of continuing medical therapy in IBD during pregnancy outweighs the potential risks in the vast majority of instances. This article will review recent developments on this topic consistent with the European Crohn's and Colitis Organization guidelines
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