127,126 research outputs found
Dem Hochedlen und Wolgelarten Herrn, Herrn Johann Ludewig Voigt aus Sachsen wolverdienten Jnspectori der Mittelwachischen und Weingärtenschen Schule überreichen bei Seiner Abreise nach Pensylvanien, dahin Derselbe als Prediger der Gemeine gerufen ward, folgende Zeilen zum Zeichen der Liebe und Freundschaft / nachstehende Präceptores gedachter Schulen J. Bär aus dem Weissenfelsischen; S. T. Bannehr aus der Altemark; S. Böhme aus Sachsen ...
No full textGlückwunschgedicht auf Johann Ludwig Voigt, Schulinspektor, zu seiner Berufung nach Pensylvanien, ca. 177025 namentlich genannte Beiträger auf dem Titelblatt erwähntAutopsie nach dem Exemplar der ULB Sachsen-AnhaltVorlageform des Erscheinungsvermerks: Halle, gedruckt bey Johann Andreas Stephan. - Erscheinungsjahr geschätzt nach Wirkungsjahren des Druckers
Harman, Stephan T., 1845-1915 : Confederate Service Record, 1906.
No full textThis service record is an account of military actions during the American Civil War by veteran Stephan T. Harman, 1845-1915, dated from 1906.All descriptive lists and service records in this United Confederate (Civil War) Veterans manuscript collection believed to be based out of Robert E. Lee Camp #158 of the United Confederate Veterans (Fort Worth, Tex.).The Southwest Collection Manuscript Record can be accessed at the following URL: http://www.lib.utexas.edu/taro/ttusw/00119/tsw-00119.html1 leaf, 2 pdf pages.Regiment & Battles mentioned: Confederate States of America. Army. Tennessee Brigade ; Atlanta Campaign, 1864
Lizards and snakes Warmth-loving sunbathers
No full textThis chapter includes the most recent advances about the study of lizards and snakes recovered in the Messel Pit (Middle Eocene), Germany.Fil: Smith, Krister T.. Senckenberg Research Institute and Natural History Museum Frankfurt. Department of Messel Research and Mammalogy. Section Palaeoherpetology; AlemaniaFil: Cernansky, Andrej. Comenius University in Bratislava. Department of Ecology; EslovaquiaFil: Scanferla, Carlos Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Bio y Geociencias del Noroeste Argentino. Universidad Nacional de Salta. Facultad de Ciencias Naturales. Instituto de Bio y Geociencias del Noroeste Argentino; ArgentinaFil: Schaal, Stephan F. K.. Senckenberg Research Institute and Natural History Museum Frankfurt. Department of Messel Research and Mammalogy; Alemani
Art piece with a review of Aaron T. Stephan: The Problem with Ladders. The
No full textArt piece with a review of Aaron T. Stephan: The Problem with Ladders. The exhibit is being presented at Whitney Art Works in Portland, through September 8
art piece on sculptor Aaron T. Stephan, creator of LIFT, which is on permane
No full textart piece on sculptor Aaron T. Stephan, creator of LIFT, which is on permanent view at the University of Southern Maine\u27s Joel and Linda Abromson Community Education Center in Portland. LIFT is a wooden table and chair set that hovers 20 feet above the ground on wooden legs. With an interview in question-and-answer format in which Stephan discusses the project and its significance
Hybrid simulation of wake vortices of landing aircraft in a turbulent environment
No full textWake-vortex evolution during landing of a long range aircraft is investigated in a turbulent environment. The simulations cover final approach, touchdown on the tarmac, and the evolution of the wake after touchdown. An ambient turbulent crosswind and headwind field is generated in a pre-simulation. The wake is initialized using a RANS-LES coupling approach. The further development of the vortical wake is investigated by large-eddy simulation until final decay. Strong three-dimensional deformations appearing after touchdown and linkings with the ground are studied. The downwind vortex is strongly advected with crosswind and decays quickly. The interaction of plate line disturbances and end effects in a turbulent environment leads to irregular decay pattern
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles
No full textRegulating molecular interactions in the T-cell synapse to prevent autoimmunity or, conversely, to boost anti-tumor immunity has long been a goal in immunotherapy. However, delivering therapeutically meaningful doses of immune-modulating compounds into the synapse represents a major challenge. Here, we report that covalent coupling of maleimide-functionlized nanoparticles (NPs) to free thiol groups on T-cell membrane proteins enables efficient delivery of compounds into the T-cell synapse. We demonstrate that surface-linked NPs are rapidly polarized toward the nascent immunological synapse (IS) at the T-cell/APC contact zone during antigen recognition. To translate these findings into a therapeutic application we tested the NP delivery of NSC-87877, a dual inhibitor of Shp1 and Shp2, key phosphatases that downregulate T-cell receptor activation in the synapse, in the context of adoptive T cell therapy of cancer. Conjugating NSC-87877-loaded NPs to the surface of tumor-specific T cells just prior to adoptive transfer into mice with advanced prostate cancer promoted a much greater T-cell expansion at the tumor site, relative to co-infusing the same drug dose systemically, leading to enhanced survival of treated animals. In summary, our studies support the application of T-cell-linked synthetic NPs as efficient drug delivery vehicles into the IS, as well as the broad applicability of this new paradigm for therapeutically modulating signaling events at the T-cell/APC interface.National Institutes of Health (U.S.) (CA140476)National Institutes of Health (U.S.) (EB123622)United States. Dept. of Defense. Prostate Cancer Research Program (W81XWH-10-1-0290)National Cancer Institute (U.S.) (Cancer Center Support (Core) Grant P30-CA14051)National Cancer Institute (U.S.)American Cancer Society (Postdoctoral Fellowship 12109-PF-11-025-01-LIB
Indirect interactions in the microbial world: specificities and similarities to plant-insect systems
No full textDe l'Opération d'Estlander, par Stephan T. Poppoff,...
No full textAppartient à l’ensemble documentaire : LangRous1Avec mode text
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