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GLI ANTIGENI DI SUPERFICIE DEL VIRUS DELL'EPATITE B: RECENTI ACQUISIZIONI ED IMPLICAZIONI PER LA STRATEGIA VACCINALE
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THE PRE-S/ANTI-PRE-S SYSTEMS REPRESENT NEW MARKERS OF THE HEPATITIS B VIRUS (HBV) WITH POTENTIAL PATHOGENETIC AND CLINICAL RELEVANCE
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HBV-DNA sequences are rarely detected in the liver of patients with HBsAg-negative chronic active liver disease and with hepatocellular carcinoma in Italy.
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Cryptogenic chronic liver disease and serum or liver hepatitis B virus markers. Their possible correlations and etiologic significance.
No full textRecettori epatocitari per albumina polimerica. Studio sperimentale su epatociti isolati ed animali in vivo.
No full textIn the present work receptors for polymerized rat serum albumin (P-RSA) were studied by incubation of radiolabelled polymers with rat hepatocytes isolated with mechanical techniques. Isolated rat hepatocytes showed a receptor activity for polymerized albumin and such a membrane receptor seems to be controlled by the cellular cytoskeleton. During rat total body scintigraphy receptor expression was detected exclusively in the liver. These observations support the hypothesis of a selective receptor activity of the liver cells for polymerized albumin. To confirm our results, further studies were performed on rat bile, after 125I-P-RSA infusion in vivo
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