732 research outputs found
Den Digitale Agora:Episode 1: Casper Steinmann
No full textI denne podcast kan du møde Casper Steinmann, der er lektor ved Institut for Kemi og Biovidenskab. Casper har stor erfaring i at arbejde med Moodle, AAU’s LMS (Learning management system). Casper benytter Moodle til at tjekke ind med sine studerende i løbet af forelæsningerne og dermed tilpasse dem løbende. Casper har utroligt mange spændende vinkler på det at undervise, så derfor har vi delt dette afsnit op i tre dele. I den første hører vi Casper tale om sit arbejde med Moodle, i andet er der fokus på brug af videoer i undervisningen og produktion af videoerne og i tredje og sidste del kan du høre om hvordan Casper laver problembaseret gamification af sin undervisning
Den Digitale Agora:Episode 1: Casper Steinmann
No full textI denne podcast kan du møde Casper Steinmann, der er lektor ved Institut for Kemi og Biovidenskab. Casper har stor erfaring i at arbejde med Moodle, AAU’s LMS (Learning management system). Casper benytter Moodle til at tjekke ind med sine studerende i løbet af forelæsningerne og dermed tilpasse dem løbende. Casper har utroligt mange spændende vinkler på det at undervise, så derfor har vi delt dette afsnit op i tre dele. I den første hører vi Casper tale om sit arbejde med Moodle, i andet er der fokus på brug af videoer i undervisningen og produktion af videoerne og i tredje og sidste del kan du høre om hvordan Casper laver problembaseret gamification af sin undervisning
Allisyn Casper Family History
Full text linkAllisyn Brielle Casper authored this family history as part of the course requirements for HIST 550/700 Your Family in History offered online in Fall 2019 and was submitted to the Pittsburg State University Digital Commons. Please contact the author directly with any questions or comments: [email protected]
Casper the Friendly Ghost: Far-Out Fables
No full text"As I fully expected, this paperback book has nothing to do with Aesopic fables. It contains standard Casper cartoon stories. I read the first, "Every Litter Bit Helps." It is rather a full story, lasting 42 pages. In typical cartoon style, it brings together contemporary concerns like littering; traditional views of fascinating things like witches and ghosts; evil characters and good characters -- Casper and his friend, Wendy, the good little witch; and happy endings. Keeping it in the collection may help some future researcher to know what kind of book it is."No Autho
A computational method for the systematic screening of reaction barriers in enzymes: searching for Bacillus circulans xylanase mutants with greater activity towards a synthetic substrate
Full text linkWe present a semi-empirical (PM6-based) computational method for systematically estimating the effect of all possible single mutants, within a certain radius of the active site, on the barrier height of an enzymatic reaction. The intent of this method is not a quantitative prediction of the barrier heights, but rather to identify promising mutants for further computational or experimental study. The method is applied to identify promising single and double mutants of Bacillus circulans xylanase (BCX) with increased hydrolytic activity for the artificial substrate ortho-nitrophenyl β-xylobioside (ONPX2). The estimated reaction barrier for wild-type (WT) BCX is 18.5 kcal/mol, which is in good agreement with the experimental activation free energy value of 17.0 kcal/mol extracted from the observed kcat using transition state theory (Joshi et al., 2001). The PM6 reaction profiles for eight single point mutations are recomputed using FMO-MP2/PCM/6-31G(d) single points. PM6 predicts an increase in barrier height for all eight mutants while FMO predicts an increase for six of the eight mutants. Both methods predict that the largest change in barrier occurs for N35F, where PM6 and FMO predict a 9.0 and 15.8 kcal/mol increase, respectively. We thus conclude that PM6 is sufficiently accurate to identify promising mutants for further study. We prepared a set of all theoretically possible (342) single mutants in which every amino acid of the active site (except for the catalytically active residues E78 and E172) was mutated to every other amino acid. Based on results from the single mutants we construct a set of 111 double mutants consisting of all possible pairs of single mutants with the lowest barrier for a particular position and compute their reaction profile. None of the mutants have, to our knowledge, been prepared experimentally and therefore present experimentally testable predictions
Freight Lubricating Oil from North of Casper, Wyo.
No full textFreight Lubricating Oil from North of Casper, Wyo
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