1,185 research outputs found

    Dynamis, the Object of a Philosophical Medicine: An Epistemological Analysis of the Treatise On Ancient Medicine

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    In this study, we propose to analyze the concept of dynamis in the treatise On Ancient Medicine that is part of the Corpus Hippocraticum. We will study it inasmuch as it constitutes a core concept on which a particular epistemological relationship between philosophy and medicine is resolved. There is an extensive hermeneutical tradition that presents this writing as the birth of a scientific medicine detached from all kinds of philosophical reflection. For the author of the letter would seem to behave like an empiricist who seeks as a doctor to get radically rid of philosophy or, at least, that ancient medicine that founds his medical practice in the philosophical theory of the elements. However, despite the partial success of this interpretive tradition, we believe that it runs the risk of offering a fragmentary and incomplete reading of the new epistemological statute that the author seeks to assign to medicine. In our opinion, the author, far from trying to expel the philosophy of practice and medical research, integrates it into a new model of scientific explanation.Fil: Gargiulo, María Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; Argentina. Universidad Nacional de Cuyo. Facultad de Filosofía y Letras. Centro de Estudios de Filosofía, Ciencia y Epistemología; Argentin

    Per le Occasioni: una lettera inedita di Montale ad Alfredo Gargiulo

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    Si pubblica una lettera inedita di Eugenio Montale ad Alfredo Gargiulo del 6 aprile 1940. Si tratta della prima testimonianza di spiegazione delle Occasioni da parte dell'autore. La lettera è una risposta alle critiche di Gargiulo pubblicate sulla Nuova Antologia.Editon and commentary of an unpublished letter by Eugenio Montale to Alfredo Gargiulo (April 6, 1940) in which it is contained the first explanation by the author about the way Le occasioni have to be read

    Per un profilo dell'anonimo autore dell'Athenaion Politeia pseudo-senofontea

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    This paper examines and discusses a number of relevant passages of the Pseudo-Xenophontic Constitution of the Athenians in order to outline a profile of its author that turns out to be slightly different from the one usually envisaged by scholars. In all likehood this person was an Athenian citizen and a shipowner, who was not so opposed to Athen's seapower as much as he was hostile to Athenian democracy. Especially important is Athenaion Politeia III 12-13 because, when he states that the atimoi in Athens are few, he is tacitly admitting that the democratic government is not guilty of wickedly abusing the political instrument of atimia against oligarchs, and this is as well an argument in favour of a not too late date of composition

    sj-docx-1-jet-10.1177_15266028231158312 – Supplemental material for Morphological and Clinical Predictors of Early/Follow-up Failure of the Endovascular Infrarenal Abdominal Aneurysm Repair With Currently Available Endografts

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    Supplemental material, sj-docx-1-jet-10.1177_15266028231158312 for Morphological and Clinical Predictors of Early/Follow-up Failure of the Endovascular Infrarenal Abdominal Aneurysm Repair With Currently Available Endografts by Enrico Gallitto, Gianluca Faggioli, Chiara Mascoli, Martina Goretti, Rodolfo Pini, Antonino Logiacco, Cristina Rocchi, Francesca Feroldi, Stefania Caputo and Mauro Gargiulo in Journal of Endovascular Therapy</p

    Erratum to: Short-Term Exposure to Enriched Environment in Adult Rats Restores MK-801-Induced Cognitive Deficits and GABAergic Interneuron Immunoreactivity Loss

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    The original version of this article unfortunately contained a mistake. The name of author was changed from "Pascual Gargiulo" to "Pascual Ángel Gargiulo. © 2017 Springer Science+Business Media, LLCUniversidad Autónoma de Chil

    Knowledge-building models for environmental planning: The case study of Bari

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    The concept of ecosystem services arises as a formal outcome of historical processes of understanding and interpreting settlements as complex ecological systems. Because of a straightforward, bottom-up demand for environment enhancement, that concept increasingly occurs in discourses, in narratives, in the demands of common people, triggering a new urban environmental awareness. This is now often arising spontaneously in the protocols of participatory construction of plans, especially when planning for the future of complex environments such as city areas. The present study tries to elicit reflections around the weight of ecosystem issues in the case study of Bari (Italy), which is experiencing an inclusive process of construction of shared knowledge for the new master plan. Starting from an initial campaign of civic walks along urban neighborhoods and a subsequent questionnaire-based survey on the community, the paper carries out comparative analyses using problem-structuring methods, in order to evaluate and reflect on community behaviors and expectations about ecosystem services

    Integrating participatory modelling in risk management

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    Participatory modelling (PM) techniques aim at involving stakeholders and local communities’ knowledge to support risks assessment management in social-ecological systems (SES). Understand SES complexity means consider unique socio-economic and cultural values, direct and indirect experiences, political characteristics that have influenced the formation of a community’s risk understanding and local knowledge. Comprehending the complexity of these interactions could help to exchange information and knowledge, leading to a better comprehension of the problem formulation through social learning processes and to facilitate conflict resolution. Evidences demonstrated that there is the need to require not only a deep understanding of the main physical phenomena to be addressed, but also a knowledge about stakeholders’ type, level of cooperation between different stakeholders and their risk perception. Once the problem is well understood, and stakeholders included in the process, it is possible to find more efficient adaptive management solutions to enhance the resilience of the system. For this reason, to improve risk management processes, it should be considered physical risk and social response in an integrated way. Starting from a literature review, the aim of this work is to demonstrate the role of PM techniques in adaptive risk management to collect knowledge and improve SES management. Specifically, coastal systems (CS) have been analysed. CS are particularly vulnerable to climate change negative impacts. In this sense, it is important to understand that vulnerability is socially constructed and not only determined by the occurrence of a physical event

    A case of thoracic ectopia cordis

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    OBJECTIVE: Ectopia cordis (EC) is a rare malformation (5-8 per million live births) characterized by an abnormal position of the heart. Based on the anatomical position it can be classified into cervical (3%), cervico-thoracic (&lt;1%), thoracic (60%), abdominal (30%), and thoracoabdominal (7%). In the most common form the heart is partially or totally exposed on the surface of the thorax through an opening in the sternum and has an open pericardial sac. The exact etiology remain unknown, the mechanism is probably an association of genetic and environmental factors. In the early stages of embryonic development, the heart is positioned outside the chest. With the normal folding of the embryo, the heart passively assumes its final position inside the pericardial sac. During the fourth week of organogenesis, the lack of complete fusion of the lateral folds in the formation of the chest wall can cause the anomaly. Another possible mechanism is the rupture of the yolk and chorionic sac, which can lead to the formation of fibrous bands that disrupt the fusion in the midline of the chest wall. An alternative theory is the mutation of the bone morphogenetic protein (BMP2) gene that plays a vital role in heart formation and ventral body closure of the chest wall. EC can be an isolated lesion or be part of Cantrell’s pentalogy, associated with the thoraco-abdominal form. As in any fetal anomaly, if one abnormality is visualized a thorough investigation of all fetal systems should be carefully analyzed. EC can occur in conjunction with major chromosomopathies, especially trisomy 18 and Turner syndrome. METHODS: A 28-year-old primigravida patient, referred to our hospital for a request of voluntary termination of an unwanted pregnancy. During the time of conception she was in therapy with an estrogen-progestin pill for contraceptive purposes, not effective maybe due to antibiotic therapy for odontopathy. Sonography has been useful to establish the gestational age and to diagnose the ectopia cordis. The patient underwent the therapeutic abortion procedure and a cytogenetic analysis of a flap of fetal skin was performed. RESULTS: Our ultrasound examination revealed a single fetus with estimated age 17th weeks of gestation. Has been reported an isolated ectopia cordis with herniation of the heart from the right chest. The remaining fetal morphology appeared regular for the gestational age. Amniotic fluid was normal. Macroscopic anatomopathological examination resulted in a female fetus weighing 148 grams, ear cups with slightly low insertion, micrognathia and bilateral clubfoot. Examination of internal organs showed an incomplete anterior development of the diaphragm with consequent weakness and compression of the two lungs by the abdominal organs (in particular by the liver). It had been reported a complete ectopia cordis of the thorax with the heart rotated posteriorly and consequent slight torsion of the aorta and pulmonary artery. Macroscopic examination of the heart did not reveal additional malformations. A deletion of the short arm of chromosome 19 was detected in 19p13.3 band, containing the OMIM: TLE6-2-5, GNA11 and GNA15, S1PR4, NCLN. CONCLUSIONS: EC is generally severe due to the frequent fetal growth restriction and high intrauterine and perinatal mortality rate. In most cases the newborn dies a few days after birth, usually by infection, major heart failure or hypoxemia. If there are no other severe cardiac malformations, surgical therapy mostly consists of covering the heart with skin, allowing some patients to survive into adulthood. Surgical treatment has a significant mortality rate. Early diagnosis with sonography is important to identify the main defect and its associated abnormalities, then counseling the patient on outcome and treatment options. EC generally has a poor prognosis, therefore termination of pregnancy should be recommended for families. Patients with thoraco-abdominal EC appear to have better outcomes, they show a survival of 45% after a mean follow-up of 5,6 years. While thoracic type has a higher mortality rate (83%). In order to establish the possible hereditary transmission, it is possible to do the Arrey- based Comparative Genomic Hybridization test (CGH-array)to investigate the genome. There is no evidence that EC is a genetically transmitted disease, however genetic analysis can be useful to provide adequate counselling for families

    A multilevel method to manage the complexity of the sustainable construction works

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    The purpose of the research described in the paper is a contribution to the definition of methods and tools for the management of sustainability in construction works, supporting decisions by the actors of the construction process involved in the decision making stages (i.e. public and private managers, designers, developers, policy makers). The paper reports on the research, adopting a multi-scale and multilevel approach in a life cycle perspective, focused on the development of inductive, logical / operational guidelines. The author shows an original interdisciplinary way to manage the complexity of a case study, where to any alternative of operation are associated aspects/impacts/performances, described by indicators connecting the building with different territorial scales
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