172 research outputs found
Swingin' along the road to victory [music] /
No full textFor voice and piano; with ukulele chord diagrams.; Cover title.; Imprint from pasted label.; "Sung by Jenny Howard."; Cover bears port. of Jenny Howard.; "Recorded on Regal-Zono, G24078-Peter Dawson, vocal. Mastertouch & Broadway Rolls."; Also available online http://nla.gov.au/nla.mus-vn5153704; Copyright for all countries, 1940 J. Albert & Son Pty. Ltd. Sydney, Melbourne & Wellington, N.Z
Supplemental Material1 - Supplemental material for Reducing return of disease activity in patients with relapsing multiple sclerosis transitioned from natalizumab to teriflunomide: 12-month interim results of teriflunomide therapy
No full textSupplemental material, Supplemental Material1 for Reducing return of disease activity in patients with relapsing multiple sclerosis transitioned from natalizumab to teriflunomide: 12-month interim results of teriflunomide therapy by Stanley L Cohan, Keith Edwards, Lindsay Lucas, Tiffany Gervasi-Follmar, Judy O’Connor, Jessica Siuta, Vineetha Kamath, Lore Garten, Chiayi Chen, James Thomas, Kyle Smoot, Kiren Kresa-Reahl and Kateri J Spinelli in Multiple Sclerosis Journal–Experimental, Translational and Clinical</p
Supplemental Material2 - Supplemental material for Reducing return of disease activity in patients with relapsing multiple sclerosis transitioned from natalizumab to teriflunomide: 12-month interim results of teriflunomide therapy
No full textSupplemental material, Supplemental Material2 for Reducing return of disease activity in patients with relapsing multiple sclerosis transitioned from natalizumab to teriflunomide: 12-month interim results of teriflunomide therapy by Stanley L Cohan, Keith Edwards, Lindsay Lucas, Tiffany Gervasi-Follmar, Judy O’Connor, Jessica Siuta, Vineetha Kamath, Lore Garten, Chiayi Chen, James Thomas, Kyle Smoot, Kiren Kresa-Reahl and Kateri J Spinelli in Multiple Sclerosis Journal–Experimental, Translational and Clinical</p
Tin Pan Alley: Propaganda in the AMerican Popular Music of George M. Cohan during WWI
No full textABSTRACT
Music during World War I was greatly influenced by and centered around a district in New York City between 5th Avenue and Broadway called “Tin Pan Alley.” There was nothing extra special about this area; it’s just where songwriters, publishers and arrangers congregated to get their inspirations and compilations for their music live. Propaganda of any kind, that proved to be effective, was used to achieve the goal of persuasion and manipulation. Propaganda in its many forms was employed nationally and internationally including but not limited to American songs, films, images, plays, African-American Musicians and the like. Tin Pan Alley was a cauldron of raw creativity.
George Michael Cohan was heavily associated with the area of New York known as Tin Pan Alley. George Michael Cohan (July 3, 1878 – November 5, 1942), known professionally as George M. Cohan, was an American entertainer, playwright, composer, lyricist, actor, singer, dancer and producer. Cohan began his career as a child, performing with his parents and sister in a vaudeville act known as "The Four Cohans." Beginning with Little Johnny Jones in 1904, he wrote, composed, produced, and appeared in more than three dozen Broadway musicals. Cohan published more than 300 songs during his lifetime, including the standards "Over There", "Give My Regards to Broadway", "The Yankee Doodle Boy" and "You're a Grand Old Flag". As a composer, he was one of the early members of the American Society of Composers, Authors, and Publishers (ASCAP). He displayed remarkable theatrical longevity, appearing in films until the 1930s, and continuing to perform as a headline artist until 1940.
The purpose of this document and its accompanying lecture recital is to demonstrate some of ways that propaganda was employed in the United States especially as evident in George Cohan’s compositions and how through successful employment of that propaganda he cemented himself in the annals of American history.
Methodologies include an exploration into the use of propaganda in America and Cohan’s biography specifically as it pertains to his composition style, performance career and professional associations because these factors seem to significantly impact the type of compositions produced by Cohan. For each setting there will be an examination of melody, harmony, rhythm, form, and texture; and an analysis of the relationship between certain communities’ feelings about the war and Cohan’s music. A comparison will be made of any significant style differences used between pro-war and anti-war propaganda. Another significant part of this research will be the iconography used during this world war, in the form of posters, pictures, magazine ads, advertisements, and jingles or commercials and how they would have subliminally “celebrated” or “shamed” citizens for their participation or lack thereof in supporting the country’s war efforts. The final chapter provides conclusions and observations based on the comparison of musical settings, the popularity of these compositions, and the impact that his music had on the American people. The lecture recital will be a distillation of the document with performance of specifically explored works to demonstrate salient aspects. An outline of the document follows is also available upon request.Embargo status: Dissertation restricted until 01/2023. To request the author grant access, click on the PDF link to the left
Reported Quality of Life in those on High Efficacy Compared to First Line Disease Modifying Therapies in a Community Cohort
No full textIntroduction: In recent years, more high efficacy disease modifying treatments (DMT) have been approved and patients are placed on high efficacy DMT earlier in their disease course. Few studies have assessed the impact of high efficacy DMT on patients’ quality of life (QoL).
Objective: The study objective was to determine whether participants on high efficacy DMT reported greater impact of MS on their physical and psychological QoL than those on first line DMT using survey data from the Pacific Northwest Multiple Sclerosis Registry (PNWMSR).
Methods: This was a cross-sectional study using participants’ last annual follow up survey submitted between 2013 and 2019. Only participants with relapsing MS who reported use of one DMT were included in the analysis. Physical and psychological QoL was measured using the Multiple Sclerosis Impact Scale (MSIS-29). High efficacy DMT included use of alemtuzumab, natalizumab, rituximab, and ocrelizumab. First line DMT included interferons, glatiramer acetate, dimethyl fumarate, teriflunomide, and fingolimod. Multiple linear regression was used to determine the difference in QoL between those using high efficacy and those on first line DMT, adjusting for age, disease duration, sex, disability, and number of relapses in the previous 12 months.
Results: Of 991 participants meeting inclusion criteria, 13% (n=127) were on a high efficacy DMT and 87% (n=864) were on a first line DMT. The mean age was 50 (±13) among high efficacy and 55 (±11) among first line DMT users; and the median disease duration was 14 years [interquartile range (IQR): 9, 20] and 16 years [IQR: 11, 21] respectively. The median physical QoL score for high efficacy DMT users was 35 [IQR: 26, 45], and 33 [IQR: 25, 44] for first line. The median psychological scores were 17 [IQR 13, 20] for high efficacy, and 16 [IQR: 12, 21] for first line. There was no evidence that MS had a greater impact on physical (β=-0.21, 95% confidence interval (CI): -2.1, 1.6) or psychological (β=-0.58, 95% CI: -1.6, 0.5) QoL for those on high efficacy compared to first line.
Conclusions: We found no difference in physical or psychological QoL between those on high efficacy and first line DMT. A limitation of this study is the smaller number of those on high efficacy DMT. While imperative to consider patients’ overall QoL when prescribing high risk DMT, we have found no difference for these medications in our analysis. The topic requires continued study with larger patient cohorts.
Disclosures:
Tamela Stuchiner: nothing to disclose. Lindsay Lucas: nothing to disclose. Elizabeth Baraban: nothing to disclose. Chiayi Chen: nothing to disclose. Stanley Cohan has served on advisory boards or steering committees for Biogen, Novartis, Sanofi Genzyme and Pear Therapeutics; has received research support from Biogen, Novartis, Sanofi Genzyme, MedDay, Mallinckrodt, Roche Genentech, and IMS Health; has received speaker honoraria from Biogen, Novartis, Sanofi Genzyme, and Roche Genentech
Fire and Life Safety Evaluation of the Christopher Cohan Center
No full textThis project is an academic exercise, as part of the MS Fire Protection Engineering program of California Polytechnic State University. The project is a culminating report with regards to life safety analysis of the Christopher Cohan Center of Cal Poly, which builds on the fundamental and applied courses of the program. The analysis is twofold, where the first part is a Prescriptive Analysis of the building and its features, followed by a Performance Based Life Safety Analysis. Both parts are performed in accordance with NFPA 101 Life Safety Code 2015 edition, Codes/Standards references within NFPA 101, and supplemented by methods of the SFPE Handbook of Fire Protection Engineering. California have yet to adopt the Life Safety Code, which per definition, makes it impossible to determine if the building is a new or existing structure. Nevertheless, the building has been analyzed as an existing building. Where noted, necessary assumptions were made to complete the analysis. The building in question is part of the Performing Arts Center of Cal Poly, and consists of assembly-, business-, and storage occupancies. Two adjacent buildings make up the remaining parts of the Performing Arts Center, but these buildings will not be analyzed in this report. The Cohan Center is separated from adjacent buildings by 4-hour rated walls, and/or separation distances of 60 ft.
The prescriptive analysis concludes that the building in general meets the requirements of the applicable codes and standards, with the following exceptions: a place of assembly at the Balcony Level have no other means of egress than through the communicating space, the spacing of smoke detectors does not meet prescriptive requirements in the Entry Lobby, and the water supply for the sprinkler system is insufficient. All conclusions are based on the information available. The recommended actions are to perform a new water flow test, and based on the result, consider installing a fire pump to provide sufficient flow and pressure to the most remote area of the sprinkler system. The performance based analysis addressed life safety in the event of fire in scenery on stage. The fire was modeled at floor level, and in the fly-gallery. Based on building inspections, the author considers ignition more likely in the fly-gallery, than at the stage floor. The main focus of this model was to evaluate consequences of smoke spread, if the proscenium wall curtain fails to deploy. The analysis concluded that the fly-gallery fire meets the performance criteria, and results in an acceptable level of life safety. The scenery fire at the stage floor fails to meet the performance criteria of the Life Safety Code, with the current building design and feature. Further analysis concludes that installing addressable smoke detectors at the stage ceiling, that activates all smoke vents and sends an alarm signal to the fire alarm control panel, resulted in meeting the performance criteria regardless of the modeled fire location
A Study on the Genetic Basis of Variation in Response to Light of Varying Wavelength and Intensity
No full textBioremediation of Volatile Organic Compounds in Indoor Spaces Using a Novel Biowall Design: A Feasibility Study
No full textIndoor air can contain volatile organic compounds (VOCs), released from household materials at concentrations ten times higher than outdoors, causing numerous health problems, and potentially cancer. Indoor biowalls present a solution to poor air quality from their ability to bioremediate VOCs with Hyphomicrobium spp., which exists on plant roots and actively consumes VOCs. Quantitative-PCR was used to assess Hyphomicrobium spp. population among four morphologically different plant species exposed to four common VOCs in enclosed aeroponic chambers with inconclusive results due to equipment failure. Additionally, an innovative biowall was designed incorporating a dissolution system into the irrigation loop to deliver VOCs to Hyphomicrobium spp. On roots via water. The dissolution system successfully absorbed 96% of isopropanol from air during experimental testing. Analysis of the prototype biowall provided unclear results due to complications with system airtightness, but resulted in multiple insights into improvements in methodology and direction of future research
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