1,508 research outputs found
Final Report of the Academic Health Center Task Force on Technology Enhanced Learning
No full textThe Task Force on Technology Enhanced Learning and Distance Education consisting of representatives from each of the schools and colleges in the Academic Health Center and the directors of the Bio-Medical Library and Academic Computing conducted an assessment and needs analysis. Based on this analysis a vision statement was formulated and a set of recommendations was prepared on how to accomplish that vision for technology enhanced learning.University of Minnesota. Academic Health Center; Speedie, Stuart M.. (2000). Final Report of the Academic Health Center Task Force on Technology Enhanced Learning. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/103778
Creating a Large Database Test Bed with Typographical Errors for Record Linkage Evaluation
No full textA conference poster presented at the American Medical Informatics Association (AMIA)'s 2008 Annual SymposiumHealth information exchange across multiple organizations requires a method or algorithm to optimally link records of the same individuals using demographic data. Selecting the best record linkage algorithm requires an evaluation to determine its sensitivity and specificity. This evaluation is facilitated by a large database test bed that closely reflects a real world population and takes into account the potential data entry errors that unfortunately occur in real-world databases. This study investigated the synthesis of such a database.Agency for Healthcare Research and Quality (AHRQ) grant number UC1 HS16155Theera-Ampornpunt, Nawanan; Kijsanayotin, Boonchai; Speedie, Stuart M.. (2008). Creating a Large Database Test Bed with Typographical Errors for Record Linkage Evaluation. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/47765
Improving Access to Clinical Information in an Emergency Department: a Qualitative Study
No full textA conference poster presented at the American Medical Informatics Association (AMIA)'s 2008 Annual SymposiumWe studied the information flow in an emergency department (ED) to understand how patient information flows between providers and how information from a computerized ambulatory system, which was not well integrated with the hospital information systems at the time, could be used. The study aimed to identify possible methods that could push information from an ambulatory EHR system to providers with minimal interference with the ED’s current workflow. The ED’s information flow was mapped and a strategy for making ambulatory encounter information available was identified.Kijsanayotin, Boonchai; Du, Jing; Theera-Ampornpunt, Nawanan; Gurses, Ayse; Speedie, Stuart M.. (2008). Improving Access to Clinical Information in an Emergency Department: a Qualitative Study. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/47764
Extension of the primary care research object model (PCROM) as clinical research information model (CRIM) for the “learning healthcare system”
No full textBackground:
Patient data from general practices is already used for many types of epidemiological research and increasingly, primary care systems to facilitate randomized clinical trials. The EU funded project TRANSFoRm aims to create a “Learning Healthcare System” at a European level that is able to support all types of research using primary care data, to recruit patients and follow patients in clinical studies and to improve diagnosis and therapy. The implementation of such a Learning Healthcare System needs an information model for clinical research (CRIM), as an informational backbone to integrate aspects of primary care with clinical trials and database searches.
Methods:
Workflow descriptions and corresponding data objects of two clinical use cases (Gastro-Oesophageal Reflux Disease and Type 2 Diabetes) were described in UML activity diagrams. The components of activity diagrams were mapped to information objects of PCROM (Primary Care Research Object Model) and BRIDG (Biomedical Research Integrated Domain Group) and evaluated. The class diagram of PCROM was adapted to comply with workflow descriptions.
Results:
The suitability of PCROM, a primary care information model already used for clinical trials, to act as an information model for TRANSFoRm was evaluated and resulted in its extension with 14 new information object types, two extensions of existing objects and the introduction of two new high-ranking concepts (CARE area and ENTRY area). No PCROM component was redundant. Our result illustrates that in primary care based research an important but underestimated portion of research activity takes place in the area of care (e.g. patient consultation, screening, recruitment and response to adverse events). The newly introduced CARE area for care-related research activities accounts for this shift and includes Episode of Care and Encounter as two new basic elements. In the ENTRY area different aspects of data collection were combined, including data semantics for observations, assessment activities, intervention activities and patient reporting to enable case report form (CRF) based data collection combined with decision support.
Conclusions
Research with primary care data needs an extended information model that covers research activities at the care site which are characteristic for primary care based research and the requirements of the complicated data collection processes
George MacLeod’s open-air preaching: performance and counter-performance
No full textStuart Blythe uses the methodology of performance to analyse George MacLeod’s open-air preaching. He points out that MacLeod’s preaching was derived from a theology of the incarnation, and an understanding of the paradoxes and dichotomies of common human life. This preaching, Blythe suggests, was also a counter-performance in the context of outlooks and ideologies inimical to the gospel. The paper raises interesting issues related to preaching as performance, and the further question as to whether or not the life and work of the Church as a whole might now be better understood as a counter-performance.Publisher PD
Redemption in the work of Francis Stuart
No full textThe idea of redemption is central to an understanding of the work
of Francis Stuart. Through an examination of its development and
expression, it is possible to demonstrate the integrity of his work and
its distinctive qualities. Such a demonstration is necessary because
Stuart's writing has been subjected to comparatively little scholarly
inquiry, although reviews of his work, especially that produced since
1949, suggest that it is impressive and important.
First, a general background to Stuart's work, a discussion of the
special problems associated with reading it, and a summary of his corpus
is provided. This indicates that the idea of redemption is important to
his earliest writing. The state of redemption is shown to be a
necessary apotheosis for Stuart's outcast heroes; it involves spiritual
suffering through which may be found a sense of reintegration and a
higher reality. This is expressed through interrelated themes such as
those of gambler, artist and ordinary man; mystic and criminal; sacred
and profane love; and spirituality and the mundane. The nature of the
redemptive experience is further elaborated by distinctive, complex
motifs, especially the hare, the ark and the woman-Christ. Their
recurrence provides an important element in the unity of Stuart's work.
Because Stuart's idea of the outcast raises important biographical
questions, an examination of the relationship between Stuart's life and
his work is made. Finally, the way in which the idea of redemption
exists in the language structures of Stuart's novels is examined, with
especial reference to his most recent work, The High Consistory. The
thesis shows that the development of the these of redemption
demonstrates the integrity of Stuart's work
John Stuart Mill’s projected science of society: 1827-1848
No full textThe purpose of the thesis is to examine John Stuart Mill’s political thought from
about 1827 to 1848 as an exercise in intellectual history. It focuses, first, on Mill’s view,
formulated by the late 1830s, that contemporary society was ‘civilized’, and second, on
his project of a science of society, which he aspired to develop in the late 1830s and
early 1840s.
By the late 1830s, Mill came to the view that his contemporary society was a
‘commercial society or civilization’, dominated by the middle, commercial class. The
first part of my thesis, constituted by Chapters 2-4, discusses the way in which Mill
formed his notion of civilization, and what he meant by the term ‘civilization’. Mill paid
attention to the implications of the rise of the middle class, and regarded such
phenomena of contemporary society as the corruption of the commercial spirit and
excessive social conformity as an inevitable consequence of the rise of the middle class.
The second part of the thesis, constituted by Chapters 5-9, examines Mill’s
projected science of society. In the late 1830s and early 1840s, Mill attempted to
develop a new science of society whose subject-matter was the nature and prospects of
commercial, civilized society. This aspiration culminated in A System of Logic,
published in 1843. In examining Mill’s projected science, I pay particular attention to
the fact that he conceived new sciences of history and of the formation of character,
both of which were indispensable in his project, although he failed to give a complete
account of these sciences. My thesis shows that the implications of his interest both in
history and in the formation of character are more significant than Mill scholars have
assumed
An Analytical Criterion for Centrifugal Instability in Non-Axisymmetric Vortices
No full textNon-axisymmetric vortices are ubiquitous in nature; examples include polar vortices in planets, the giant red spot in Jupiter, tornadoes and cyclones on Earth, mesoscale eddies in the ocean. Turbulent flows are furthermore known to be dominated by small- and large-scale vortex structures. Owing to the wide range of applications, knowledge of conditions under which a given vortex becomes unstable is beneficial. Here, the centrifugal instability of two-dimensional, non-axisymmetric vortices in the presence of an axial flow and a background rotation is studied using the local stability approach. The local stability approach, based on geometric optics and similar in formulation to the rapid distortion theory \cite{bib:godeferd2001}, considers the evolution of shortwavelength perturbations along streamlines in the base flow. This approach, developed by Lifschitz Hameiri \cite{bib:lifschitz1991}, is particularly useful for base flows for which a global stability analysis is computationally expensive. A sufficient criterion for centrifugal instability in an axisymmetric vortex with and is first derived by analytically solving the local stability equations for wave vectors that are periodic upon evolution around a closed streamline. This criterion is then heuristically extended to non-axisymmetric vortices and written in terms of integral quantities on a streamline. The criterion is then shown to be accurate in describing centrifugal instability over a reasonably large range of parameters that specify Stuart vortices and Taylor-Green vortices
A colorimetric PCR method for the detection of M. leprae in skin biopsies from leprosy patients
No full textA one-tube nested polymerase chain reaction (PCR) method for the diagnosis of paucibacillary leprosy was developed using the repetitive RLEP sequence as a target. Detection of the PCR products was simplified by the adaptation of a colorimetric method. The test was specific for Mycobacterium leprae, and the sensitivity of the assay was 1 fg of purified genomic M. leprae DNA (less than one genome). Complete concordance was seen between the development of color and resolution on agarose gels. The results of frozen skin sections from untreated patients showed that the assay could detect 100% of multibacillary samples [bacterial index (BI) of 2 or more] and 69% and 70% of the samples with Bis of 1 and 0, respectively. The use of one-tube nested PCR in assessing the effectiveness of multidrug therapy (MDT) in leprosy also was determined. The simplified colorimetric assay was found to be sensitive, rapid and specific, and is suitable for use in routing diagnostic laboratories.Peer reviewedfinal article publishe
Cologny, Fondation Martin Bodmer, M-48.1 : John Stuart Mill, <i>Note on Freedom of Speech</i>, signed autograph
No full textFollowing enlightenment philosophers, liberal thinkers - which include Mill - considered freedom of speech a fundamental human right. In this small autograph, with embossed monogram "JSM", consisting of three folios intended for dispatch, the philosopher copies a passage of his famous "On Liberty" from 1869, taken from chapter II: "Of the Liberty of Thought and Discussion." Mill emphasizes that humankind no more has the right to silence a single opinion than it has the right to silence all of humankind, if it had the power to do so. Before it became the property of Martin Bodmer, this letter had been purchased by the author Stefan Zweig in 1923.Online Since: 2017-06-2
- …
