7,288 research outputs found
Tim Spector: Butter or margarine? Food religion challenged Tim Spector professor of genetic epidemiology:Butter or margarine? Food religion challenged
No full textBeyond the gene roundtable discussion
No full textThis virtual discussion between biomedical researchers and academics in the literary humanities took place in June–July 2013, through the medium of blog and email. The participants are Tim Spector (Genetic Epidemiology), Karen Temple (Medical Genetics), Angelique Richardson (Literary Studies), Deborah J.G. Mackay (Human Genetics) and Peter Garratt (Literary Studies). The conversation was initiated and convened by Mandy Bloomfield (Literary Studies). What develops in the course of the discussion is a sense of the ways in which biomedical researchers working on genetics are discovering new complexities with profound cultural and philosophical implications, whilst those working in the humanities are considering what those implications might be, but from a position on the edges of specialist scientific knowledge and modes of thinking. Perhaps inevitably, we sometimes find we are not speaking quite the same language. And this question of language – of metaphors, varieties of meaning, precision and indeterminacy – crops up time and again in this discussion. Perhaps it is in these frictive edges between disciplines that productive dialogue can happen, and we can learn from the differences between perspectives. For example, in this discussion the ‘nurture–nature’ dichotomy is interrogated in different ways, but with equivalent levels of reflective rigour, by researchers in the biomedical and humanities disciplines alike. What do we really mean by those terms? What are the historical components of this conceptual divide? Is it even possible to separate ‘nurture’ from ‘nature’? If a consensus emerges from this discussion, it is that current research in both the sciences and the humanities is blurring the distinctions between such dichotomous constructions as ‘nature vs. nurture’ in ways that are changing thinking and practices across the disciplines. Whether this takes us to a revaluation of Victorian understandings of organism and environment, or into ever-more complicated relationships between medical practitioners and their patients, we are, as one participant puts it, ‘in for an interesting time'
Statins as modulators of bone formation
No full textThe use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) to reduce serum cholesterol is well described. However, the recent finding that statins have direct effects on bone was unexpected. A number of epidemiological studies have recently been published that explore the effects of statins on bone mineral density and risk of fracture in humans. Statins may act by directly stimulating the expression of bone morphogenetic protein-2 and increasing osteoblast differentiation or, like nitrogen-containing bisphosphonates, may have effects on the mevalonate pathway that leads to inhibition of osteoclast activity and osteoblast apoptosis. In addition, the demonstration that statins can inhibit inflammation and encourage angiogenesis offers other possibilities for action
Do dolphins benefit from nonlinear mathematics when processing their sonar returns?
No full textAn interview with author Tim Leighton about the paper
Opportunities for linking young surveyors across professional surveying member organisations and FIG
No full textTim Di Muzio on 'Sabotage'
No full textIn a series of essays published in 2013 and 2014 on capitaspower.com, political economist Tim Di Muzio explored the concept of ‘sabotage’ as it applies to capitalist power. I recently rediscovered these essays and was so impressed by them that I have reposted them here as a single piece.
About the author: Tim Di Muzio is a researcher at the University of Wollongong. He is the author of numerous books, including Debt as power, Carbon capitalism, and The 1% and the Rest of us
1996-1997 Tim Gautreaux
No full textTim Gautreaux is the author of three novels and two earlier short story collections. His work has appeared in The New Yorker, The Best American Short Stories, The Atlantic, Harper’s, and GQ. After teaching for thirty years at Southeastern Louisiana University, he now lives, with his wife, in Chattanooga, Tennessee. (Photo credit: Randy Bergeron)https://egrove.olemiss.edu/grisham_res/1023/thumbnail.jp
First person - Tim Petzold
Get PDFFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Tim Petzold is first author on ‘ Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification’, published in BiO. Tim conducted the research described in this article while a PhD student in Julien Bertrand's lab at the Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Switzerland. He is now a postdoc in the lab of Holger Gerhardt at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, investigating developmental biology – previously his focus was on how blood stem cells develop and now it has shifted to how the vascular system develops
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