1,721,013 research outputs found
Clinical evaluation of a carbon fiber reinforced composite material as a scaffold in the anterior cervical interbody fusion”.
No full text
Evidence of type II estrogen receptor in human osteoblast-like cells
No full textOsteoblast-like cells isolated from human bone bioptic specimens were characterized and analysed for the presence of type II estrogen receptor (type II EBS). The amount of type II EBS was measured by a whole-cell assay at 4 °C for 2.5 h using [3H]-estradiol as tracer. Saturation analysis, used to investigate the binding characteristic of type II EBS, resulted in a sigmoid curve. Scatchard analysis showed the binding affinity of the estrogen receptor, yelding a concave plot. The dissociation constant (K(d)), determined from the [3H]-estradiol concentration required for half saturation was about 12 ± 2 nM (SD). The number of type II EBS, estimated at maximum binding, was 197,000 ± 8800 sites per cell. If the regulation of the receptor by flavonoids would be confirmed, the evidence of type II EBS in osteoblast-like cells could suggest a direct action of ipriflavone and others flavonoids on bone density in postmenopausal osteoporosis
Unilateral uniplanar modular external fixator for percutaneous proximal femoral osteotomy in children: surgical technique
No full textVarus derotation femoral osteotomy (VDFO) is a commonly used surgical procedure in association with pelvic osteotomy for dislocated hip in developmental hip dysplasia. Several types of internal fixation devices were described in the literature, but none of them showed a superiority or a lower rate of complication over the others. Different types of external fixator were also described for proximal osteotomy fixation with good results. We describe the surgical technique of the VDFO using a modular external fixator with an illustrative case
Bone remodelling around ceramic implants: a histomorphometrical evalua¬tion.Congresso congiunto IORS-SISC. Varese. 30 giugno-2 luglio 1996
No full textEvaluation of fracture healing with the computerized analysis of radiographic images
No full textThe radiographic evaluation of fracture healing in the long bones utilizes subjective and hardly analytic standards. Therefore, to solve this problem, the authors suggest using a computerized image processing system which increases radiographic informative content and allows an objective evaluation of fracture healing. We analyzed the radiographs of 15 patients suffering from femoral fracture and treated by means of Küntscher nailing. We processed the radiographs taken both before and 1, 2, 4, and 6 months after surgical treatment. It was thus possible to select the regions of interest, to graph brightness levels and to measure both distances and areas. Computerized image processing provides an objective and quantitative analysis of radiographs and allows an increase in informative content. It also allows the comparison of pre- and postoperative radiographs with those taken at different times. Our results may confirm the utility of computerized image analysis of radiographs to evaluate bone remodelling during fracture healing
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