625 research outputs found

    PBM und Outcome

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    Predictors associated with mortality of extracorporeal life support therapy for acute heart failure: single-center experience with 679 patients

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    BACKGROUND: Extracorporeal life support (ECLS) therapy is increasingly used for cardiac and respiratory support postcardiotomy, refractory cardiogenic shock and cardiopulmonary resuscitation. This study aims to describe in-hospital mortality of patients requiring ECLS, identify independent predictors associated with mortality and analyze changes of mortality over time. METHODS: This retrospective study includes all adult ECLS cases at the University Hospital Zurich, a designated ECLS center in Switzerland, in the period 2007 to 2019. RESULTS: ECLS therapy was required in 679 patients (median age 60 years, 27.5% female). In-hospital mortality was 55.5%. Cubic spline interpolation did not detect evidence for a change in mortality over the whole period of 13 years. In-hospital mortality significantly varied between ECLS indications: 70.7% (152/215) for postcardiotomy, 67.9% (108/159) for cardiopulmonary resuscitation, 47.0% (110/234) for refractory cardiogenic shock, and 9.9% (7/71) for lung transplantation and expansive thoracic surgery (P<0.001). Logistic regression modelling showed excellent discrimination in the receiver operating characteristic (ROC) area under the curve (AUC) of 0.89 [95% confidence interval (CI): 0.87–0.92] and identified significant mortality predictors: age, simplified acute physiology score (SAPS) II, as well as new liver failure and each allogenic blood transfusion unit given per day. ECLS after cardiopulmonary resuscitation was associated with significantly higher mortality compared to ECLS for refractory cardiogenic shock. CONCLUSIONS: In-hospital mortality of patients treated with ECLS therapy is high. Outcomes have not changed significantly in the observed period. We identified age, SAPS II, new liver failure and each allogenic blood transfusion unit given per day as independent mortality predictors. Knowledge of predictors strongly associated with in-hospital mortality may affect future decisions about ECLS indications and the respective management to use this elaborate therapy more effectively

    Is patient blood management cost-effective? Response to Br J Anaesth 2020 https://doi.org/10.1016/j.bja.2020.09.003.

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    Refers toKevin M. Trentino, Donat R. Spahn, Hamish S. Mace, Hans Gombotz, Axel HofmannIs patient blood management cost-effective? Comment on Br J Anaesth 2020British Journal of Anaesthesia, Available online 26 September 2020, Pages</div

    Cataglyphis laylae Cedric A. Collingwood & Donat Agosti & Mostafa R. Sharaf & Antonius van Harten 2011, nov. spec.

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    Cataglyphis laylae Collingwood nov. spec. Plates 96–103 Cataglyphis desertorum Forel, 1894, teste Collingwood, 1985; unavailable name according to Agosti (1990). Specimens examined: Holotype: 1 ☿, United Arab Emirates, al-Ain [24°13'N 55°46'E], iii.1995, leg. C.A. Collingwood (MHNG). Paratypes: 3 ☿, al-Ain zoo, 13.iii.2005, CAC. 1 ☿, Remah, 9.iii.1995, CCA. 3 ☿, Remah, resthouse, 250 m, irrigated sand dune [24°10'37"N 55°18'6"E], 18.iii.1995, leg. D. Agosti. 6 ☿, Remah, resthouse, 250 m, irrigated sand dune, nest with one entrance, [24°10'37"N, 55°18'6"E], 18.iii.1995, leg. D. Agosti. 1 ☿, Sharjah Desert Park, 5–6.x.2004, AvH; 1 ☿, 3.iii.2005, CAC. 1 ☿, al- Za'aba, 100 m, sandy soil with Rhaisa stricta [23°43'20"N, 55°33'49"E], 22.iii.1995, leg. D. Agosti. Description: A large worker from al-Ain was selected as holotype. The measurements are as follows: total length 8.40; head width 3.60; head length 4.20; scape length 3.84; funicular segment I 0.40; funicular segment II 0.23; petiole length 1.10; petiole width 0.72. Colour dark reddish brown. There are no exterior hairs on the scapes or hind tibia. The gaster, petiole and propodeum have dorsal hairs. Remarks: This species thought to correspond with C. desertorum has to be described as a new species. In fact it is one of the commonest Cataglyphis in southern Arabia. The main distinguishing feature compared with other dark Cataglyphis is the slender petiole, which has the anterior face more sloped than in other similar species such as C. niger (André, 1882) and C. savignyi (Dufour, 1862). Biology: Cataglyphus laylae nov. spec. does not appear to occur in open sandy desert and is most abundant in disturbed habitats such as man-developed plantations and open cultivated fields. Distribution: This species was recorded by Collingwood (1985) as C. desertorum from Saudi Arabia and Oman and as Cataglyphis spec. by Collingwood & Agosti (1996). Etymology: The new species is named after a village settlement called “Layla”, just north of Riyadh (Saudi Arabia) in the area where the author (CAC) first encountered it in numbers in an Acacia plantation.Published as part of Cedric A. Collingwood, Donat Agosti, Mostafa R. Sharaf & Antonius van Harten, 2011, Order Hymenoptera, family Formicidae, pp. 1-70 in Arthropod fauna of the UAE 4 on page 54, DOI: 10.5281/zenodo.116858

    7.5. PBM in der Gynäkologie und Geburtshilfe

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    Patient Blood Management: the new standard

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