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    Soyer, HP

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    Regression of atypical nevus: An anecdotal dermoscopic observation

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    BACKGROUND Clark nevi (atypical melanocytic nevi) can be considered as risk markers and potential precursors of melanoma. The authors report on the morphologic changes of an atypical nevus by dermoscopic follow-up examination over a 7-year period. CASE REPORT A 43-year-old man had a brown macule on his back, sized 5 mm, with an irregular shape, clinically and dermoscopically diagnosed as an equivocal melanocytic lesion. Dermoscopically during the initial examination, a predominant reticular pattern with peripheral eccentric hyperpigmentation in the lower portion of the lesion could be seen. After 7 months, the area of peripheral eccentric hyperpigmentation had regressed, and after 4.5 years the atypical pigment network had almost disappeared. After 7 years of follow-up, a diffuse area of hypopigmentation and a residual light brown pigmentation were detectable. The histopathologic diagnosis was consistent with an atypical junctional nevus with regression with features of a Clark nevus. CONCLUSION Based on our observation, even a dermoscopically atypical nevus may undergo regression as documented by long-term dermoscopic follow-up

    Commentary: Dermoscopy

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    The introduction of dermoscopy into the clinical practice of dermatology has disclosed a new and fascinating morphologic dimension of pigmented skin lesions. Dermoscopy is a noninvasive, simple, and inexpensive diagnostic technique that permits the visualization of morphologic features that are not visible to the naked eye, thus forming a link between macroscopic clinical dermatology and microscopic dermatopathology. This “submacroscopic” observation of pigmented skin lesions enriches the available clinical diagnostic tools by providing new morphologic criteria for the differentiation of melanoma from other melanocytic and nonmelanocytic pigmented skin lesions. Over the past years, dermoscopy has been known by a variety of names, including skin-surface microscopy, epiluminescence microscopy, incident-light microscopy, dermatoscopy, and videodermatoscopy. The term “dermoscopy,” however, currently enjoys the greatest international consensus

    Dermoscopy of pigmented skin lesions - a valuable tool for early diagnosis of melanoma

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    The clinical use of dermoscopy has uncovered a new and fascinating morphological dimension of pigmented skin lesions. Dermoscopy is a non-invasive diagnostic technique that links clinical dermatology and dermatopathology by enabling the visualisation of morphological features not seen by the naked eye. Close examination of pigmented skin lesions in this way increases the effectiveness of clinical diagnostic tools by providing new morphological criteria for distinguishing melanoma from other melanocytic and non-melanocytic pigmented skin lesions.In the past, dermoscopy has been known by various names, including skin surface microscopy, epiluminescence microscopy, incident light microscopy, dermatoscopy, and videodermatoscopy. However, the term 'dermoscopy', first used by Friedman and colleagues in 1991 , is the most widely used
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