241 research outputs found

    Image Selection Code for Automated Dicentric Chromosome Identification

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    <p>Image Selection for Metaphase Images in Automated Dicentric Chromosome Identification<br> Author: Yanxin Li, Jin Liu<br> Correspondence: Peter K. Rogan, Ph.D, [email protected]</p> <p>This code is for the following paper:<br> Accurate cytogenetic biodosimetry through automated dicentric chromosome curation and metaphase cell selection<br> Jin Liu, Yanxin Li, Ruth Wilkins, Farrah Flegal, Joan H. Knoll, Peter K. Rogan</p> <p>List of files and folders:<br> DemoSample1: metaphase images for DemoSample1<br> DemoSample2: metaphase images for DemoSample2<br> DemoSample1.adcisample: ADCI sample file generated by ADCI software for DemoSample1.<br> DemoSample2.adcisample: ADCI sample file generated by ADCI software for DemoSample2.<br> ADCI sample files contain area and filters information of images which is required by Image Selection code.<br> DemoScript.py: Image Selection code</p> <p>Prerequisites for the Image Selection code:<br> Python 2. Code is tested in Python 2.7.6<br> NumPy</p> <p>How to run:<br> Run DemoScript.py. Make sure DemoSample1.adcisample and DemoSample2.adcisample are in the same folder as DemoScript.py.</p> <p>Results:<br> For each sample, the code will display image names in descending order of quality, measured by Group Bin Distance or Combined Z Score (using weight 434521).<br> To evaluate the sorting, view metaphase images in DemoSample1 or DemoSample2 folders.</p&gt

    Metal-containing and Metal-free systems for small molecule activation

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    The objective of this thesis is to investigate small molecule activation with metal-containing and metal-free systems. Chapter 2 describes a tri-aryl benzene ligand scaffold for multimetallic N2 activation. A RuCp* complex was synthesized and characterized by NMR and X-ray crystallography. It offered an easy entry to understanding of the ligand coordination environment. Additionally, several multi-iron complexes were also obtained even though they were not the desired products. However, they still demonstrated the feasibility of using this ligand to effect multimetallic chemistry. Chapters 3 to 5 describe a series of compounds with charge-separation feature. These compounds could not only bind CO2 reversibly, but also catalyze the hydroboration of CO2 with a wide borane scope. In Chapter 3, a possible intermediate from the catalytic cycle was isolated and it partly revealed the mechanism of the catalytic reaction.Ph.D

    Metal-containing and Metal-free systems for small molecule activation

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    The objective of this thesis is to investigate small molecule activation with metal-containing and metal-free systems. Chapter 2 describes a tri-aryl benzene ligand scaffold for multimetallic N2 activation. A RuCp* complex was synthesized and characterized by NMR and X-ray crystallography. It offered an easy entry to understanding of the ligand coordination environment. Additionally, several multi-iron complexes were also obtained even though they were not the desired products. However, they still demonstrated the feasibility of using this ligand to effect multimetallic chemistry. Chapters 3 to 5 describe a series of compounds with charge-separation feature. These compounds could not only bind CO2 reversibly, but also catalyze the hydroboration of CO2 with a wide borane scope. In Chapter 3, a possible intermediate from the catalytic cycle was isolated and it partly revealed the mechanism of the catalytic reaction.Ph.D

    Night and Fog of Hong Kong: Balancing development and polycentric urban model exploration of Hong Kong in Pearl River Delta, Urban regeneration strategies in search for improving cohesion at Tin Shui Wai new town within the Hong Kong extended region

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    Due to the restricted functional collaboration between Hong Kong and Shenzhen Region as well as Pearl River Delta, the functional construction of Hong Kong Region becomes a mono-centric system which leads to a serious unbalanced development between its city centre and its peripheral new towns with great potential. However, the new planning document of both Chinese Mainland and Hong Kong are looking forward to an advanced cooperation between Hong Kong and Shenzhen into an extended region to explore new possibilities of Hong Kong development under the Pearl River Delta background.Architecture, Urbanism and Building Sciences | Complex Citie

    Validation of Nonlinear Finite Element Analysis on Reinforced Concrete Slab under Concentrated Out-of-plane Load Combined with Uniaxial In-plane Load Based on Case Study

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    Finite element analysis is becoming a popular tool for engineers recently. Nonlinear finite element analysis is more advanced due to that it can deal with the nonlinearity of structures, which leads to more accurate approximation of structural behaviour. In Model Code 2010, nonlinear finite element analysis, which belongs to the higher level of approximation, can predict the structural behaviour with refined physical parameters but by devoting more time to the analysis. This leads to better accuracy. Thus, it is important to study how to apply nonlinear finite element analysis to approximate the structural strength.When it comes to the existing design codes, the shear design methods of reinforced concrete slabs loaded in uniaxial in-plane force are developed from the tests of beams rather than slabs, which may lead to the underestimation of the design resistance. Through experiments of seven slabs, a related study of the validity of existing shear design methods has been performed by Bui et al. (2017). However, there is no existing literature about the application of nonlinear finite element analysis towards the reinforcement concrete slabs mentioned above so far. In this thesis, one single nonlinear finite element analysis is applied to seven slabs of experiment to study the validation of nonlinear finite element analysis on the RC slabs without shear reinforcement loaded in concentrated out-of-plane load and uniaxial in-plane loads. The validation is studied by comparing results from finite element analysis, experiment and finite element analysis from Nana et al. (2017), which mainly includes shear load – displacement curve, development of crack pattern, failure modes and the influence of uniaxial load on the structural behaviour. In addition, the shear capacity under uniaxial in-plane load is studied by comparing results from analytical assessment based on existing codes, experiment and nonlinear finite element analysis. When compared with experiment, nonlinear finite element analysis shows a close shear capacity of all seven slabs but stiffer structural behaviour. The development of cracks is similar to the observation of experiment. The failure modes indicated by nonlinear finite element analysis is more likely punching shear rather than one-way shear that is demonstrated in the experiment. The influence of increasing uniaxial compression on shear capacity is larger than what is observed in experiment while increasing tension has smaller influence. By comparing the prediction of shear capacity from experiment, existing codes and nonlinear finite element analysis, it can be concluded that NLFEA is unconservative in prediction of shear capacity of the RC slabs without shear reinforcement loaded in concentrated out-of-plane loads and uniaxial in-plane loads. Some suggestions are given for further study. Improvement of modelling is suggested. For instance, finer mesh could lead to more accurate results, and insights of bond-slip reinforcement could generate more precise results. Furthermore, the study of safety formats is suggested in further study to consider the uncertainty due to random variation of material properties. In addition, more experiments and nonlinear finite element analysis are suggested to get insights of the influence of uniaxial loads on structural behaviour of RC slabs without shear reinforcement. Civil Engineering | Structural Engineering | Concrete Structure

    A Study of the Application of Safety Formats in Non-linear Finite Element Analysis of Reinforced Concrete Tunnel Segment

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    The application of non-linear finite element analysis is important nowadays to simulate the real behavior of structure. A sort of non-linear finite element analysis with and without safety formats referring to Model Code 2010 is applied in this thesis, to study the FEM simulation of the shear capacity of reinforced concrete structure. A case study is based on a tunnel segment experiment. Comparative analysis is performed to study how valid safety formats are in practice. In addition, the influence of fracture energy to shear capacity is also discussed applying different calculation methods stated in Model Code 1990 and Model Code 2010 respectively.Additional thesis

    Machine Learning Detection and Analysis on Obfuscated Android Malware

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    University of Technology Sydney. Faculty of Engineering and Information Technology.Android is the leading mobile operating system, accounting for more than 80% of the market share. Millions of Android apps exist in various app markets such as GooglePlay, AppChina, Huawei app store, etc. The success of Android has attracted the interest of hackers who build thousands and even millions of Android malware that are distributed over the app markets. Detecting such malware is thus of the utmost importance to preserve the security and privacy of billions of Android app users. In this thesis, the author focuses on three main research challenges. First, the author investigates the problem of Android malware labeling. This is a key challenge that needs to be overcome to build reference datasets, to then be able to use AI techniques. Second, he investigates the impact of obfuscation and deobfuscation on the detection of piggybacked apps. Finally, he studies the problem of generating relevant testing samples (i.e., adversarial samples) to assess antivirus products

    Author Correction: A Satellite Imagery Dataset for Long-Term Sustainable Development in United States Cities

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    Correction to: Scientific Data, published online 04 December 2023 In this article the author name Jingtao Ding was incorrectly written as Jintao Ding. The original article has been corrected.</p
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