266 research outputs found
Ladder Bottom-up Convolutional Bidirectional Variational Autoencoder for Image Translation of Dotted Arabic Expiration Dates
No full textThis paper proposes an approach of Ladder Bottom-up Convolutional Bidirectional Variational Autoencoder (LCBVAE) architecture for the encoder and decoder, which is trained on the image translation of the dotted Arabic expiration dates by reconstructing the Arabic dotted expiration dates into filled-in expiration dates. We employed a customized and adapted version of Convolutional Recurrent Neural Network CRNN model to meet our specific requirements and enhance its performance in our context, and then trained the custom CRNN model with the filled-in images from the year of 2019 to 2027 to extract the expiration dates and assess the model performance of LCBVAE on the expiration date recognition. The pipeline of (LCBVAE+CRNN) can be then integrated into an automated sorting systems for extracting the expiry dates and sorting the products accordingly during the manufacture stage. Additionally, it can overcome the manual entry of expiration dates that can be time-consuming and inefficient at the merchants. Due to the lack of the availability of the dotted Arabic expiration date images, we created an Arabic dot-matrix True Type Font (TTF) for the generation of the synthetic images. We trained the model with unrealistic synthetic dates of 60,000 images and performed the testing on a realistic synthetic date of 3000 images from the year of 2019 to 2027, represented as yyyy/mm/dd. In our study, we demonstrated the significance of latent bottleneck layer with improving the generalization when the size is increased up to 1024 in downstream transfer learning tasks as for image translation. The proposed approach achieved an accuracy of 97% on the image translation with using the LCBVAE architecture that can be generalized for any downstream learning tasks as for image translation and reconstruction.* Corresponding author E-mail address: ghadasoliman@orangecom Received: 14 April 2024; Accepted: 28 August 2024; Published: 30 September 202
sj-docx-1-urj-10.1177_03915603231192737 – Supplemental material for The potential effect of ambrisentan as monotherapy and combined with tadalafil on diabetic erectile dysfunction in rats
No full textSupplemental material, sj-docx-1-urj-10.1177_03915603231192737 for The potential effect of ambrisentan as monotherapy and combined with tadalafil on diabetic erectile dysfunction in rats by Omnia Azmy Nabeh, Fatma Ahmed El-Batrawy, Omayma Anwar Khorshid and Ghada Farouk Soliman in Urologia Journal</p
Supplemental Material - Development and validation of a novel poisoning agitation-sedation score for predicting the need for endotracheal intubation and mechanical ventilation in acutely poisoned patients with disturbed consciousness
No full textSupplemental Material for Development and validation of a novel poisoning agitation-sedation score for predicting the need for endotracheal intubation and mechanical ventilation in acutely poisoned patients with disturbed consciousness by Soha A. Abd Elghany, Heba I. Lashin, Ghada N. El-Sarnagawy, Merfat M. Oreby, and Eman Soliman in Human & Experimental Toxicology.</p
The inventory of youth employment programs in Egypt : a snapshot of a dynamic field
No full textPrepared by: Ghada Barsoum; Passant Elwy; Hanan Khayal; Nada Kassem; Mai Amr; Amal Soliman; Yara Hassan; and Marian FakhryLiteraturverzeichnis Seite 21-2
[The inventory of youth employment programs in Egypt] : [a snapshot of a dynamic field]
No full text[Prepared by: Ghada Barsoum; Passant Elwy; Hanan Khayal; Nada Kassem; Mai Amr; Amal Soliman; Yara Hassan; and Marian Fakhry]Literaturverzeichnis Seite 31-33 in englischer Sprache. Abweichende Seitenzählung der Druck- und Online-AusgabeText arabischArabisc
A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route
No full textThe use of nanocarrier delivery systems for direct nose to brain drug delivery shows promise for achieving increased brain drug levels as compared to simple solution systems. An example of such nanocarriers is emulsomes formed from lipid cores surrounded and stabilised by a corona of phospholipids (PC) and a coating of Tween 80, which combines the properties of both liposomes and emulsions. Oxcarbazepine (OX), an antiepileptic drug, was entrapped in emulsomes and then localized in a poly(lactic acid-co-glycolic acid)-poly(ethylene glycol)-poly(lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) triblock copolymer thermogel. The incorporation of OX emulsomes in thermogels retarded drug release and increased its residence time (MRT) in rats. The OX-emulsome and the OX-emulsome-thermogel formulations showed in vitro sustained drug release of 81.1 and 53.5%, respectively, over a period of 24 h. The pharmacokinetic studies in rats showed transport of OX to the systemic circulation after nasal administration with a higher uptake in the brain tissue in case of OX-emulsomes and highest MRT for OX-emulsomal-thermogels as compared to the IN OX-emulsomes, OX-solution and Trileptal® suspension. Histopathological examination of nasal tissues showed a mild vascular congestion and moderate inflammatory changes around congested vessels compared to saline control, but lower toxic effect than that reported in case of the drug solution
Derivatives combining the fragment of pyrazinamide and 4-aminosalicylic acid as antimycobacterial compounds
No full textCharles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical chemistry and Pharmaceutical analysis Author: Petr Šlechta Supervisor: doc. PharmDr. Jan Zitko, Ph.D. Consultant: MSc. Ghada Basem Bouz, Ph.D. Title of diploma thesis: Derivatives combining the fragment of pyrazinamide and 4-aminosalicylic acid as antimycobacterial compounds According to WHO, tuberculosis (TB) is the leading cause of death from a single infectious organism worldwide and the number of cases with drug resistant TB is still increasing, creating the need for new antituberculotics. Therefore, we report design, synthesis and antimicrobial evaluation of a series of hybrid compounds combining different pyrazinamide derivates and p- aminosalicylic acid as potential antituberculotic agents. The compounds were prepared by mixing different pyrazinecarboxylic acids, after activation by 1,1'-carbonyldiimidazole, with p- aminosalicylic acid in dimethylsulfoxide as a solvent. Obtained compounds were in vitro tested for their antimycobacterial activity against M. tuberculosis H37Rv, M. tuberculosis H37Ra and four other mycobacterial strains. Prepared compounds were also in vitro screened for antibacterial, antifungal, and cytotoxic (HepG2) activity. Most compounds showed antimycobacterial activity in range of..
Dietary Cholesterol and the Lack of Evidence in Cardiovascular Disease
No full textCardiovascular disease (CVD) is the leading cause of death in the United States. For years, dietary cholesterol was implicated in increasing blood cholesterol levels leading to the elevated risk of CVD. To date, extensive research did not show evidence to support a role of dietary cholesterol in the development of CVD. As a result, the 2015–2020 Dietary Guidelines for Americans removed the recommendations of restricting dietary cholesterol to 300 mg/day. This review summarizes the current literature regarding dietary cholesterol intake and CVD. It is worth noting that most foods that are rich in cholesterol are also high in saturated fatty acids and thus may increase the risk of CVD due to the saturated fatty acid content. The exceptions are eggs and shrimp. Considering that eggs are affordable and nutrient-dense food items, containing high-quality protein with minimal saturated fatty acids (1.56 gm/egg) and are rich in several micronutrients including vitamins and minerals, it would be worthwhile to include eggs in moderation as a part of a healthy eating pattern. This recommendation is particularly relevant when individual’s intakes of nutrients are suboptimal, or with limited income and food access, and to help ensure dietary intake of sufficient nutrients in growing children and older adults
The Arab Intellectual as a Woman: The Writings of Ghada Samman
No full textGhada Samman (b. 1942) is a prominent literary figure with an established legacy across the Arabic-speaking world. Through her widely-acclaimed writings, the Syrian author, journalist, and critic occupies a unique position in Arab intellectual circles as a woman who combines a commitment to the peoples’ causes with an innovative literary style vividly capturing the estrangement faced by the modern Arab subject. Samman has spent her life in exile, first in Beirut and eventually settling in Paris when the Lebanese Civil War (1975-1990) escalated. She has published 10 poetry books, 6 short story collections, 5 novels, and 20 collections of essays. However, despite her influential writings, Samman is relatively unknown outside of the Arabic-speaking world and a negligible portion of her corpus has been translated into English. My presentation posits the reason for this exclusion being that the Anglophone world does not know where to place Samman as she refuses the mould of “women’s writing” to which the Western academy is accustomed. Hers is the broad, interdisciplinary concern of the intellectual, writing on themes of exile, diatribes against capitalism and classism, the liberation of sexuality from prescribed norms, as well as how patriarchal hegemonies victimise both men and women. Even in the Arabic-speaking world she has pushed back against reductive labelling of her work, writing in a 1987 article: ‘My allegiance is to my freedom and my faith in a woman’s ability to write great human literature. There’s no need to call it “feminist” when its defence of women is part and parcel of its defence of all who are oppressed in Arab societies.’ My presentation will explore the life and work of Ghada Samman from the position of an Arab intellectual rather than a limited (and expected) reading of her as a woman writer exclusively concerned with “women’s issues”
- …
