37,727 research outputs found
Dr Robert King author
No full textDr. Robert King is pictured at the medical office on display at the Bishop Museum. King was the author of "A history of the practice of medicine in Manatee County, Florida", published in 1985. He was also a past president of the Manatee Historical Society
Robert Gendler's Astronomy Pictures
No full textRobert Gendler is an amateur astronomer with an extensive online gallery of his astronomy images. His pictures are available in high resolution on the web and for purchase in print form through his website. The author also provides links to additional resources which include: astronomical objects, an astronomy primer for beginners, an image gallery and external links. This is a nice resource for those interested in visual aspects of astronomy. Most of the resources are available free of charge, but the author does provide high resolution prints for sale
OMP Peptides Activate the DegS Stress-Sensor Protease by a Relief of Inhibition Mechanism
No full textIn the E. coli periplasm, C-terminal peptides of misfolded outer-membrane porins (OMPs) bind to the PDZ domains of the trimeric DegS protease, triggering cleavage of a transmembrane regulator and transcriptional activation of stress genes. We show that an active-site DegS mutation partially bypasses the requirement for peptide activation and acts synergistically with mutations that disrupt contacts between the protease and PDZ domains. Biochemical results support an allosteric model, in which these mutations, active-site modification, and peptide/substrate binding act in concert to stabilize proteolytically active DegS. Cocrystal structures of DegS in complex with different OMP peptides reveal activation of the protease domain with varied conformations of the PDZ domain and without specific contacts from the bound OMP peptide. Taken together, these results indicate that the binding of OMP peptides activates proteolysis principally by relieving inhibitory contacts between the PDZ domain and the protease domain of DegS.United States. Dept. of Energy (Office of Basic Energy Sciences, contract DE-AC02-06CH11357))National Institutes of Health (U.S.) (NIH-NCRR award RR-15301)National Institutes of Health (U.S.) (NIH postdoctoral fellowship (F32AI-074245-01A1))National Institutes of Health (U.S.) (NIH grant AI-16892
Spectral analysis of vertical temperature profile time-series data in Yellowstone Lake sediments
No full textAuthor Posting. © American Geophysical Union, 2021. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Water Resources Research 57(4), (2021): e2020WR028430, https://doi.org/10.1029/2020WR028430.We use yearlong vertical temperature profile time-series (seven thermistors at evenly spaced depth intervals from 10 to 70 cm) from five sites in and around the Deep Hole thermal area, southeast of Stevenson Island, Yellowstone Lake, to investigate heat and mass fluxes across the lake floor. The records demonstrate that thermal gradients in surficial sediments are modulated by a rich spectrum of bottom water temperature variations generated by hydrodynamic processes, and that sites inside the thermal area also respond to hydrothermal variations. We develop and implement a new method for estimating the sediment effective thermal diffusivity and pore fluid vertical flow rate that exploits the full spectrum of observed temperature variations to generate the parameter estimates, uncertainties, and metrics to assess statistical significance. Sediments at sites outside thermal areas have gradients of ∼7.5°C/m, in situ thermal diffusivities of ∼1.6 × 10−7 m2/s consistent with highly porous (80–90%) siliceous sediments, and experience hypolentic flow in the upper ∼20 cm. Sites inside the Deep Hole thermal area exhibit considerable spatial and temporal variability, with gradients of 1–32°C/m, and higher thermal diffusivities of ∼2–12 × 10−7 m2/s, consistent with hydrothermal alteration of biogenic silica to clays, quartz, and pyrite. Upward pore fluid flow at these sites is observed across multiple depth intervals, with maximum values of ∼3 cm/day. The observed spatial and temporal variability within the thermal area is consistent with upward finger flow combined with short wavelength convection within the porous sediments above a steam reservoir.This research was supported by the National Science Foundation Grants EAR-1516361 to Robert A. Sohn and EAR-1515283 to Robert N. Harris, and by the Independent Research and Development Program at the Woods Hole Oceanographic Institution (Robert A. Sohn). All work in Yellowstone National Park was completed under an authorized Yellowstone research permit (YELL-2018-SCI-7018)
Robert Ingpen: Author and Illustrator
No full textFilmed Tuesday 30 June, 1:00pm at Northern Territory Library, Parliament House Darwin.
Robert tells of the background to his commission to the design of the coat-of-arms and flag for the Northern Territory (0? 12 minutes) and his main activity in recent years illustrating a library of children's classic books culminating in September 2015 with Alice Through the Looking Glass. He also talks about his recent work with the National Library of Australia in publishing books for children using the resources of the national archive. One of these books is Tea and Sugar Christmas which is shortlisted in the 2015 Children's Book Council of Australia Book Awards.
Robert Ingpen is one of Australia's most successful illustrators and has written and/or illustrated more than 100 published books. In 1986 Robert became the only Australian to be awarded the Hans Christian Andersen Medal for Illustration, recognising "complete works which have made a lasting contribution to children's literature". Often called the "Little Nobel Prize", the Hans Christian Andersen Award is the highest international recognition given to an author and an illustrator of children's books
Pauline A. Young Papers
No full textPauline Alice Young, a distinguished educator, librarian, historian, and civil rights activist, was born in 1900. Her impactful career included teaching, lecturing, and extensive community involvement. Young's lifelong commitment to equality and civil rights advocacy left an indelible mark on Delaware, earning her numerous awards and a place in the Hall of Fame of Delaware Women in 1982.
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Emerging Trends and Technologies in the Information Ecosystem, December 10, 2021
No full textPresentation: "Trends in Collections and Analytics"and "Post-COVID Academic Library Trend-forecasting with a Focus on HBCUs"December’s Emerging Trends presentations provided tips on using technology for the creation and delivery of information. Madhu Kadiyala, Robert L. Fallen, Stephanie Bernard, and Suteera Apichatabutra share their knowledge from the Collections and Content Management Department, “Trends in Collections and Analytics.” There are many trends in the field of collections in the last few years. The whole serials market has been shaken up by mass cancellations, price changes, more document delivery choices, and changes in the way serials are used. Database products are transforming from collections of articles to “one stop shops” containing e-books, conference papers, videos, and many other publication formats. New analytics tools allow us to have detailed views of usage and complex views of collections. Open access materials are becoming better and more plentiful. The market is full of mergers and company acquisitions. “Collections as a service” is a fairly new buzz word, and there are recent cooperative collection projects that aim to preserve predictable numbers of copies of printed text as libraries move to more electronic delivery. In Jessica Epstein's presentation, "Post-COVID Academic Library Trend-Forecasting with a Focus on HBCUs," she covered topics ranging from the impact of access to a physical library space, issues of digital divide, device preferences during pandemic online learning and trend forecasting for Atlanta University Center Robert W. Woodruff Library
Stephanie Mathson interviews essayist and memoirist Robert Root
No full textEssayist and memoirist Robert Root, professor of English at Central Michigan University, talks about his book "Recovering Ruth" and the genealogical research research in his work and his role as both a university professor and an author. He also shares his views on creative nonfiction, Michigan as a source of inspiration, and works in progress. Root is interviewed by Stephanie Mathson of the Michigan State University Libraries for the MSU Libraries' Michigan Writers Series
Dr. Robert Threatt, Interviewed by Loretta Parham, September 24, 2012
No full textVideo interviews with a complementing monograph providing reflections of former presidents of Historically Black Colleges and Universities discussing leadership, mission, challenges, successes, and issues of race and education. Interviewer: Loretta Parham, CEO & Library Director, Atlanta University Center Robert W. Woodruff Library. Interviewee: Dr. Robert Threatt, President, Morris Brown College 1973-1991
Garment made by Dr. Robert Hillestad
No full textPhotograph of garment made by Betts' scholar, Dr. Robert Hillestad. Garment is displayed on mannequin with arms spread out to showcase drapery and texture
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