2,009 research outputs found

    Chinas monetary ambitions: RMB internationalization in comparative perspective

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    What is the political process of Chinas move to internationalize its home currency? How different is Chinese RMB internationalization from the currency internationalization of other great powers? What is the international destiny of the RMB? By addressing such questions, this study challenges three prevailing views of RMB internationalization: realist determinism, American exceptionalism, and liberal hype. This article argues that a feedback model can be useful for our understanding of the process timing and direction of RMB internationalization. This study also identifies key similarities and differences among Germany of the 1930s, the United States of the 1960s, and todays China in their currency internationalization. This comparison will reveal important structural factors that may contribute to a slow path to full RMB internationalization, and the emergence of the hybrid model of Chinacentered monetary order in the East Asian region.OAIID:RECH_ACHV_DSTSH_NO:T201507626RECH_ACHV_FG:RR00200001ADJUST_YN:EMP_ID:A080441CITE_RATE:0DEPT_NM:정치외교학부EMAIL:[email protected]_YN:NN

    Un amour singulier dans la poésie de circonstance de Ronsard

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    Sohn Joo-Kyoung. Un amour singulier dans la poésie de circonstance de Ronsard. In: Réforme, Humanisme, Renaissance, n°65, 2007. pp. 25-42

    Corticosteroid-induced bradycardia in multiple sclerosis and maturity-onset diabetes of the young due to hepatocyte nuclear factor 4-alpha mutation: A case report

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    BACKGROUND: Intravenous steroid pulse therapy is the treatment of choice for acute exacerbation of multiple sclerosis (MS). Although steroid administration is generally well-tolerated, cases of cardiac arrhythmia have been reported. Herein, we describe a young woman who developed marked sinus bradycardia and T-wave abnormalities after corticosteroid administration. We also present plausible explanations for the abnormalities observed in this patient. CASE SUMMARY: An 18-year-old woman experienced vertiginous dizziness and binocular diplopia 1 wk prior to admission. Neurological examination revealed left internuclear ophthalmoplegia with left peripheral-type facial palsy. The initial laboratory results were consistent with those of type 2 diabetes. Brain magnetic resonance imaging revealed multifocal, non-enhancing, symptomatic lesions and multiple enhancing lesions. She was diagnosed with MS and maturity-onset diabetes of the young. Intravenous methylprednisolone was administered. On day 5 after methylprednisolone infusion, marked bradycardia with T-wave abnormalities were observed. Genetic evaluation to elucidate the underlying conditions revealed a hepatocyte nuclear factor 4-alpha (HNF4A) gene mutation. Steroid treatment was discontinued under suspicion of corticosteroid-induced bradycardia. Her electrocardiogram changes returned to normal without complications two days after steroid discontinuation. CONCLUSION: Corticosteroid-induced bradycardia may have a significant clinical impact, especially in patients with comorbidities, such as HNF4A mutations

    H-\infinity loop-shaping 기법을 이용한 가압경수형 원자력 발전소의 급수제어기 개발

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    학위논문(박사) - 한국과학기술원 : 원자력및양자공학과, 2010.2, [ x, 103 p. ]In this thesis, a robust \It{H-\infin} loop-shaping controller for the steam generator (SG) feedwater control system of the KSNP (Korean Standard Nuclear Power Plant), a 1000MWe pressurized water reactor with vertical U-tube type steam generators (UTSG) is developed. The SG feedwater control system maintains the SG water level by controlling the feedwater flowrate using feedwater control valves. In order to develop the robust \It{H-\infin} controller, SG models for the control of feedwater to the KSNP UTSG are identified. As the first step of SG model identification, a precise SG mathematical thermal-hydraulic model is built using the RELAP5/MOD3 system simulation computer code. The developed RELAP5/MOD3 SG model is inadequate to be used for the design of controller due to its complexities. Thus, the SG thermal-hydraulic model needs to be simplified while maintaining required accuracy in describing the principal dynamics of the SG. For this, as the second step, a series of model experiments using the developed thermal-hydraulic model are performed in order to acquire input-output data sets representing the SG characteristics in terms of SG water level dynamics as a function of the feedwater flowrate, steam flowrate, feedwater temperature, and reactor power. As the final step, the \Bf{Simple Process Models} are applied to create a simple, continuous-time process SG model for control. The input-output data sets obtained from the model experiments using the RELAP5/MOD3 SG model are utilized in developing the algorithm to describe static gain, dominating time constants, and a possible delay of transfer function of the SG system. Since the SG operating characteristics are strongly dependent on the operating power level, the SG operating range from 0 to 100% power is divided into 10 sub-operating points based on the plant operation experiences as well as the operating modes of the KNSP SG. A number of robust \It{H-\infin} controllers for the SG models iden...한국과학기술원 : 원자력및양자공학과

    High throughput single-molecule technology

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    Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.BN/Chirlmin Joo LabSports & GamesBN/Bionanoscienc

    A Wrist-Type Fall Detector with Statistical Classifier for the Elderly Care

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    Falls are one of the most concerned accidents for elderly people and often result in serious physical and psychological consequences. Many researchers have studied fall detection techniques in various domain, however none released to a commercial product satisfying user requirements. We present a systematic modeling and evaluating procedure for best classification performance and then do experiments for comparing the performance of six procedures to get a statistical classifier based wrist-type fall detector to prevent dangerous consequences from falls. Even though the wrist may be the most difficult measurement location on the body to discern a fall event, the proposed feature deduction process and fall classification procedures shows positive results by using data sets of fall and general activity as two classes

    The Importance of Bright Spotty Lesions on Magnetic Resonance Imaging in Predicting Chronic Neuropathic Pain in Myelitis

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    Background/Objectives: Chronic neuropathic pain (CNP) stands as one of the most debilitating complications in patients with myelitis owing to its challenging management. Bright spotty lesions (BSLs) are frequently observed in neuromyelitis optica spectrum disorder (NMOSD), but few reports have discussed CNP in myelitis. We aim to demonstrate that BSLs could be one of the potential prognostic factors for CNP development in myelitis. Methods: We examined 63 patients diagnosed with myelitis. Patients were categorized into CNP and non-CNP groups. We assessed the severity of clinical symptoms and the oral steroid dose administered after pulse therapy. Spine magnetic resonance imaging (MRI) of each patient was reviewed to analyze the characteristics of myelitis. Serological and cerebrospinal fluid (CSF) findings were also examined to confirm the etiology. Results: CNP was observed in 27 patients (42.9%). The mean onset age of patients with CNP was 45.26 ± 14.16 years. The MRI lesions exhibited more enhanced features and bright spotty lesions (BSLs) in the CNP group (χ2 test, p < 0.05). Patients with CNP received a lower oral steroid dose during the first month after symptom onset (χ2 test, p < 0.05). Multivariate logistic regression analysis revealed that patients with CNP exhibited significant BSLs in their myelitis lesions on spine MRI (OR 4.965; 95% CI, 1.282 to 19.235, p = 0.02). Conclusions: Although the exact mechanism remains unknown, the presence of BSLs on spine MRI could serve as an independent prognostic factor for CNP development. Additionally, our study suggests that lower oral steroid doses administered immediately after symptom onset are associated with CNP development. Further investigation with a larger cohort is warranted to validate our findings

    sj-docx-1-npx-10.1177_1934578X221075079 - Supplemental material for Ethanol Extract of <i>Elaeagnus glabra f. oxyphylla</i> Branches Alleviates the Inflammatory Response Through Suppression of Cyclin D3/Cyclin-Dependent Kinase 11<sup>p58</sup> Coupled to Lipopolysaccharide-Activated BV-2 Microglia

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    Supplemental material, sj-docx-1-npx-10.1177_1934578X221075079 for Ethanol Extract of Elaeagnus glabra f. oxyphylla Branches Alleviates the Inflammatory Response Through Suppression of Cyclin D3/Cyclin-Dependent Kinase 11p58 Coupled to Lipopolysaccharide-Activated BV-2 Microglia by Hye-Sun Lim, Eunjin Sohn, Yu Jin Kim, Bu-Yeo Kim, Joo-Hwan Kim and Soo-Jin Jeong in Natural Product Communications</p

    Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L

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    Background: Atopic dermatitis is a chronic, allergic inflammatory skin disease that is accompanied by markedly increased levels of inflammatory cells, including eosinophils, mast cells, and T cells. Arctium lappa L. is a traditional medicine in Asia. This study examined whether a butanol extract of A. lappa (ALBE) had previously unreported anti-allergic or anti-inflammatory effects.Methods: This study examined the effect of ALBE on the release of ��-hexosaminidase in antigen-stimulated-RBL-2H3 cells. We also evaluated the ConA-induced expression of IL-4, IL-5, mitogen-activated protein kinases (MAPKs), and nuclear factor (NF)-��B using RT-PCR, Western blotting, and ELISA in mouse splenocytes after ALBE treatment.Results: We observed significant inhibition of ��-hexosaminidase release in RBL-2H3 cells and suppressed mRNA expression and protein secretion of IL-4 and IL-5 induced by ConA-treated primary murine splenocytes after ALBE treatment. Additionally, ALBE (100 ��g/mL) suppressed not only the transcriptional activation of NF-��B, but also the phosphorylation of MAPKs in ConA-treated primary splenocytes.Conclusions: These results suggest that ALBE inhibits the expression of IL-4 and IL-5 by downregulating MAPKs and NF-��B activation in ConA-treated splenocytes and supports the hypothesis that ALBE may have beneficial effects in the treatment of allergic diseases, including atopic dermatitis. �� 2011 Sohn et al; licensee BioMed Central Ltd

    Circadian preference and trait impulsivity, sensation-seeking and response inhibition in healthy young adults

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    Circadian preference has been considered related with impulsivity. The purpose of the present study was to evaluate the relationship between circadian typology and impulsivity measured by the Barratt Impulsivity Scale (BIS), sensation-seeking measured by the Sensation Seeking Scale - Form V (SSS-V) and response inhibition elicited by the GO/NO-GO paradigm. A total of 503 Korean healthy college students (288 males and 215 females) completed the Composite Scale of Morningness (CSM) for circadian typology and the BIS and SSS-V for impulsivity and risk taking, respectively. A subset of 142 subjects additionally performed the computerized GO/NO-GO task for motor response inhibition. A significant association was found between the circadian typology of the CSM and impulsivity of the BIS and disinhibition of SSS-V. In addition, there was a difference in trend level between the circadian typology and response inhibition elicited by the GO/NO-GO test. Regarding circadian preference, evening types were significantly associated with higher impulsivity on the BIS, disinhibition on the SSS-V and lower rate of successful inhibition on the GO/NO-GO task compared to morning types. The present results showed significant relationships between circadian preference and impulsivity and sensation-seeking personality traits. In particular, our findings suggest that high impulsivity, disinhibition and impaired response inhibition are more related to evening types. Circadian preference might be associated with psychiatric problems interacting with some aspects of personality traits such as inhibitory control.ope
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