144 research outputs found
Astragalus wui M. Idrees & Z. Y. Zhang 2021, nom. nov.
No full textAstragalus wui M. Idrees & Z.Y. Zhang, nom. nov. Replaced name:— Astragalus sylvaticus Y.H. Wu (2015: 718), nom. illeg., non A. sylvaticus (Pall.) Willd. (1802: 1300). Type:— CHINA. Xinjiang: Yecheng Country, Sukepiya, in border forest, alt. 3000 m, 15 Aug. 1987, Exped. Qinghai-Tibet Wu Yuhu 1067 (holotype: QTPMB, not seen). Etymology:—The specific epithet honours Prof. Dr. Wu Yuhu (Northwest Institute of Plateau Biology, Chinese Academy of Science, Xining, China), author of the replaced name, who first described this new species.Published as part of Idrees, Muhammad & Zhang, Zhiyong, 2021, Astragalus wui, a new replacement name for A. sylvaticus Y. H. Wu (Galegeae, Papilionoideae, Fabaceae), pp. 210-211 in Phytotaxa 524 (3) on page 210, DOI: 10.11646/phytotaxa.524.3.6, http://zenodo.org/record/564936
Salix diazii M. Idrees & J. M. H. Shaw 1015, nom. nov.
No full textSalix × diazii M. Idrees & J.M.H. Shaw, nom. nov. Replaced name:— Salix × longissima T.E.Díaz & J.Andrés (1987: 132), nom. illeg., non S. longissima P.Wessel (1855: 140). Type:— SPAIN. Léon Province: La Martina, 490 m, 29TPH91, 16 June 1985, T.E. Díaz et al. s.n. (holotype, LEB29538!, isotypes LEB29539!, LEB30605!). Etymology:— The specific epithet honours Prof. Dr. Tomás Emilio Díaz González (University of Oviedo, Oviedo, Spain), author of the replaced name, for his tremendous contributions to the taxonomy of the genus Salix. Distribution:— Spain, Léon Province (La Martina).Published as part of Idrees, Muhammad & Shaw, Julian M. H., 2022, A new name for extant Salix × longissima T. E. Díaz & J. Andrés (Salicaceae), pp. 213-214 in Phytotaxa 550 (2) on page 213, DOI: 10.11646/phytotaxa.550.2.11, http://zenodo.org/record/664103
End- of- Life Care: Beneficence Undermines Patient’s Autonomy
No full textEnd-of-life care is a decision-making process in which health care providers, patients, and their families play a crucial role in easing the suffering of the patients and their families. Usually, end-of-life decision-making takes place in a critical situation of the patient; therefore, health care providers, particularly, physicians and nurses play a major role in making a decision for the patient’s life with regards to updated knowledge and practice. In this view, health care providers face many challenges in end-of-life decision-making due to controversy among equally unfavorable solutions; particularly between two ethical principles i.e., patient autonomy and beneficence. Health care providers often overweigh beneficence over autonomy regarding less suffering for the patient and his/her family. This approach of health care providers raises a question for undermining patients' autonomy and violating the basic ethical right of a patient. To overcome these kinds of ethical challenges, it is imperative to equip health care providers with updated knowledge of advance directives for patients. In addition, patients and their families should be well informed from the beginning to the end stage of the patient stay in the hospital. Besides, each hospital should have an ethical expert committee including nurses to analyze the entire situation and to make the decision in the best interest of the patient and his/her family
SLiMEnrich Y2H Case Study
No full textSupplementary example data for "SLiMEnrich: computational assessment of protein-protein interaction data as a source of domain-motif interactions" by Sobia Idrees, Åsa Pérez-Bercoff and Richard J Edward
Structural analysis and epitope prediction of HCV E1 protein isolated in Pakistan: an in-silico approach
No full textPredicting motif mimicry in viruses
No full textOne of the main pursuits in proteomics is to understand the complex network of protein-protein interactions (PPI) that underpin biological processes. Two major classes of PPI are domain-domain interactions (DDI) between globular proteins, and domain-motif interactions (DMI) between a globular domain and a short linear motif (SLiM) in its partner. Advances in high-throughput experimental techniques have been applied at large-scale in an attempt to characterise the interactomes of various organisms. However, the PPI networks identified by these high-throughput experiments have low resolution as compared to low-throughput technologies, such as protein co-crystallization. Furthermore, large-scale approaches may be poor at capturing low affinity or transient interactions, which includes the majority of known DMI. To date, several studies have been conducted to identify how well these PPI data can capture protein complexes, but the ability of high-throughput PPI-detection methods to capture DMI remains a largely unanswered question.
Here, a new computational pipeline (SLiMEnrich) was designed to assess how well a given source of PPI data captures DMIs and thus, by inference, how useful that data should be for SLiM discovery. To help system biologists choose appropriate methods for predicting different types of interactions, a comparison study of existing high-throughput PPI datasets was performed. PPI data, SLiM predictions, domain composition and known SLiM-domain binding partnerships were integrated to identify possible DMI and DDI within interactomes. SLiMEnrich identified PPI data that were enriched for DMI or DDI by randomising the PPI within the network to generate a background expectation. Moreover, it was found that host-pathogen PPI data can be used to study molecular mimicry in viruses and to discover novel SLiMs. An in-silico peptide exchange approach was developed and applied to provide additional validation of predicted mimicry candidates. Despite limitations of this technique in large-scale validation of predicted SLiMs and DMIs, peptide exchange simulations identified a few high-confidence SLiMs that are likely to bind known structures and therefore constitute strong candidates for molecular mimicry by human viruses
Exploring teachers\u27 conceptions and practices reading written feedback in nursing school, Karachi, Pakistan
No full textPurpose This study aimed to identify the teachers\u27 conceptions and practices of written feedback in nursing schools in Karachi. Methodology A cross-sectional descriptive study design was used to recruit the study participants from I 1 nursing schools recognized by the Pakistan Nursing Council in Karachi. The data was collected through a structured questionnaire and analyzed through SPSS version-I9. Results In terms or teachers\u27 beliefs about WFB, most of the teachers agreed that WFB is as important as verbal feedback and students improve their work after receiving feedback from their teachers. Moreover, nearly, 50% of the participants thought that negative feedback leads to poor evaluation of the teacher by the students. In the practice of providing WFB, the majority of the study participants reported that most of the time, the area of focus of providing WFB to the students is the content on the paper, compared to the grammatical accuracy of the paper, followed by assignment guidelines. Majority of the participants revealed that they do not have time to discuss WFB with the students; however, when circumstances allow, they discuss it with the students on an individual basis. With regard to the factors affecting the quality of WFB, teachers identified teachers\u27 lack of training, distracting environment, and workload of the teacher were important factors. Conclusion The participants acknowledged the importance of both verbal and written feedback; however, they highlighted some factors (teachers\u27 lack of training, workload, distracting environment, and teacher-student relationship) that affect the quality of written feedback. Based on the findings of this study, the most important of all the recommendations is the suggestion to address the dire need for providing teachers training in the practice of giving WFB. Secondly, institutions should have unified policy to motivate teachers for providing WFB to their students
Rubus coreanus var. nakaianus H. Leveille 1910
No full text5. Rubus coreanus var. nakaianus Léveillé (1910: 358) Type (lectotype designated here):— KOREA. Quelpaert: in silvis Hallaisan, June 1909, T. Taquet 2845 (barcode E00313541!). [Image available at https://data.rbge.org.uk/herb/ E00313541]. Note:— Léveillé (1910) cited three collections (Taquet 2834, 2835 & 2845)” in the protologue when he described this variety, but did not indicate the holotype specimen. In addition, no author has designated a lectotype, even inadvertently (Art. 7.11 of ICN). According to Stafleu and Cowan (1979), all of the Léveillé’ type specimens have been purchased by E in 1919. We locate three collections, one of them “ Taquet 2834 ” deposited in E (barcode 00010578), one of them “ Taquet 2835 ” in E (barcode 00313542), and the other material “ Taquet 2845 ” in E (barcode E00313541); all these collections should be regarded as syntypes (Art. 9.6 of ICN). All the specimens in E bear the information “ Syntype Rubus coreanus var. nakaianus H. Léveillé ”, and it is necessary to select one of them as the lectotype (Art. 9.12 of ICN). Hence, we designate the blooming specimen of “ T. Taquet 2845 ” in E (barcode E00313541) as the lectotype. The selected sheet bear the same locality and is morphological complete with the presence of stem, leaves, and flower that fully correspond with the protologue.Published as part of Idrees, Muhammad & Zhang, Zhiyong, 2022, Lectotypification of 16 names in Rubus subg. Idaeobatus, 12 names in R. subg. Malachobatus, and 1 name in R. subg. Chamaebatus (Rosaceae), pp. 13-24 in Phytotaxa 559 (1) on page 15, DOI: 10.11646/phytotaxa.559.1.2, http://zenodo.org/record/700928
Rubus ourosepalus Cardot 1917
No full text29. Rubus ourosepalus Cardot (1917: 290) Type (lectotype designated here):— W. CHINA. July 1903, E.H.Wilson 3484 (barcode P00755302!, isolectotypes: A00040689!, A00133085!). [Image available at http://coldb.mnhn.fr/catalognumber/mnhn/p/p00755302]. Note:—In the protologue, Cardot (1917) described Rubus ourosepalus and cited “ Wilson 1903; Veitch Exped. 3484 ” as the type, but did not indicate where the type preserved. Since then, no author has designated a lectotype, even inadvertently (Art. 7.11, Turland et al. 2018). According to Stafleu and Mennega (1995), Cardot’ original materials were deposited at P. We locate three duplicates, two of them deposited in A (barcode 00040689 and 00133085), and one of them in P (barcode 00755302). All these collections should be regarded as syntypes (Arts. 9.6, and 40 Note 1, Turland et al. 2018); hence, a lectotype may be designated (Art. 9.12). We designate the sheet in P (barcode 00755302) as the lectotype, since it is morphological complete with the presence of stem, leaves, and flower that fully correspond with the protologue.Published as part of Idrees, Muhammad & Zhang, Zhiyong, 2022, Lectotypification of 16 names in Rubus subg. Idaeobatus, 12 names in R. subg. Malachobatus, and 1 name in R. subg. Chamaebatus (Rosaceae), pp. 13-24 in Phytotaxa 559 (1) on page 21, DOI: 10.11646/phytotaxa.559.1.2, http://zenodo.org/record/700928
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