2,726 research outputs found
Alerting and orienting in Alzheimer's disease - are they independent? Reply to Festa et al
No full textThe area of contention between E. Festa-Martino, B. R. Ott, and W. C. Heindel (2004; see record 2004-12990-007) and A. Tales and colleagues (A. Tales, J. L. Muir, A. Bayer, R. Jones, & R. J. Snowden, 2002; A. Tales, J. L. Muir, A. Bayer, & R. J. Snowden, 2002; see record 2002-06031-015) is whether the Alzheimer's disease (AD)-related increased spatial orienting effect is attributable directly to the decreased phasic alerting effect or whether they are two separate effects. In a subsequent study, A. Tales, R. J. Snowden, M. Brown, and G. Wilcock (2006; see record 2006-20657-014) have provided evidence to suggest that the increased spatial orienting effect in AD is not necessarily the result of a decreased phasic alerting effect, as an AD-related increase in spatial orienting effect occurred under conditions in which the phasic alerting effect was the same for both groups. In a commentary to this article, E. K. Festa, B. R. Ott, and W. C. Heindel (2006; see record 2006-20657-015) discuss what they suggest may be potential confounding factors within the authors' study. In this reply, further data in support of the authors' interpretation are provided, and the authors address the points highlighted by Festa et al. (2006). In addition, the authors request that if Festa et al. (2006) are to account for the changes in spatial orienting effects in AD in terms of the shifts in the phasic alerting effects, then how do they postulate how so small a change in one can produce so large a change in the other? (PsycINFO Database Record (c) 2007 APA, all rights reservedThe area of contention between E. Festa-Martino, B. R. Ott, and W. C. Heindel (2004; see record 2004-12990-007) and A. Tales and colleagues (A. Tales, J. L. Muir, A. Bayer, R. Jones, & R. J. Snowden, 2002; A. Tales, J. L. Muir, A. Bayer, & R. J. Snowden, 2002; see record 2002-06031-015) is whether the Alzheimer's disease (AD)-related increased spatial orienting effect is attributable directly to the decreased phasic alerting effect or whether they are two separate effects. In a subsequent study, A. Tales, R. J. Snowden, M. Brown, and G. Wilcock (2006; see record 2006-20657-014) have provided evidence to suggest that the increased spatial orienting effect in AD is not necessarily the result of a decreased phasic alerting effect, as an AD-related increase in spatial orienting effect occurred under conditions in which the phasic alerting effect was the same for both groups. In a commentary to this article, E. K. Festa, B. R. Ott, and W. C. Heindel (2006; see record 2006-20657-015) discuss what they suggest may be potential confounding factors within the authors' study. In this reply, further data in support of the authors' interpretation are provided, and the authors address the points highlighted by Festa et al. (2006). In addition, the authors request that if Festa et al. (2006) are to account for the changes in spatial orienting effects in AD in terms of the shifts in the phasic alerting effects, then how do they postulate how so small a change in one can produce so large a change in the other? (PsycINFO Database Record (c) 2007 APA, all rights reserve
Alerting and orienting in Alzheimer's disease.
No full textRecently, researchers (E. Festa-Martino, B. R. Ott, and W. C. Heindel, 2004; A. Tales, J. L. Muir, A. Bayer, R. Jones, and R. J. Snowden, 2002; A. Tales, J. L. Muir, A. Bayer, and R. J. Snowden, 2002 have found significantly abnormal spatial orienting together with the abolishment of the alerting effect in Alzheimer's disease (AD). However, these research groups differed in their interpretation of the results. A. Tales, J. L. Muir, A. Bayer, R. Jones, and R. J. Snowden (2002) and A. Tales, J. L. Muir, A. Bayer, and R. J. Snowden (2002) explained their data in terms of two independent processes, whereas E. Festa-Martino et al. (2004) interpreted their findings as indicative of an inverse association, namely that the increased spatial orienting effect in AD was the direct result of the abolition of the phasic alerting effect. In this further study examining exogenous spatial orienting and phasic alerting, the authors present evidence to suggest that the increased spatial orienting effect in AD is not the result of a decreased phasic alerting effect
Reformulating the rj-McMC Algorithm for 3D Inversion of Passive Seismic Data for Near-Surface Characterization
No full textGeophysical subsurface characterization techniques could, due to their non-invasive nature, play a crucial role in the design and subsequent construction of infrastructure in urban & industrial environ- ments. Geo-data specialist company Fugro sees potential in upgrading their current ambient-seismic- noise-tomography workflow, to make use of state-of-the-art inversion schemes with the main goal of increasing the quality and accuracy of the initial-site characterization delivered to clients. In this thesis I explore the feasibility of utilizing the reverse-jump Markov chain Monte Carlo (rj-McMC) algorithm for the inversion of ambient seismic noise for characterization in urban & industrial environments. Specif- ically, testing the potential of scaling down this inversion algorithm to fit in a small scale, near-surface framework. To achieve this, I first carried out analyses to evaluate the appropriate Rayleigh wave frequency range, after which realistic noise hyperparameters, suited for this reduced scale problem, were obtained. Because of the potential exploitation of in-situ borehole measurements, I reformulated the Bayesian prior within the rj-McMC algorithm to implement these constraining shear wave velocity values appropriately. I conducted extensive synthetic experiments to gain insight into the behavior of this adapted algorithm, from which it was concluded that the inherent dynamic discretization partially prevents these constraints from being implemented to their full extent. Nevertheless, promising results lead me to conclude that the use of the rj-McMC algorithm for application in near-surface urban & industrial environments is feasible.Applied Geophysics | IDEA Leagu
Clowns, Fools, and Killers: An Exploration of Horror, Comedy, and Madness Through the Roles of Murderer 2 and Sir Richard Ratcliffe in William Shakespeare\u27s Richard III
No full textThis document is a thesis submitted in partial fulfillment of the Master of Fine Arts degree in Theatre Arts with a Concentration in Musical Theatre. It is a detailed account of author RJ Magee’s artistic and scholarly process in creating the roles of Murderer 2 and Sir Richard Ratcliffe in William Shakespeare’s Richard III. The production was performed as part of Minnesota State University, Mankato’s mainstage season in October of 2022. In five chapters, this thesis chronicles the actor’s process: a preproduction analysis, a historical and critical perspective, a rehearsal and performance journal, a post-production analysis, and a process development analysis. Appendices and works cited are included
Extension of displacement limits in multiple-exposure sequences of apparent motion.
No full textIn order to examine the processes by which motion signals are combined over time, we presented subjects with random dot kinematograms which could vary in terms of the number of frames in the sequence and the duration between the onset of each stationary frame. Performance (as measured by the greatest displacement at which subjects could discriminate opposite directions of movement) improved with increasing number of displacements up to around 5 displacements, whilst manipulations of the frame duration had no affect upon this figure. Thus the results cannot be described in terms of a limited integration time. By creating sequences in which no dots underwent more than a single displacement we show that the improvement is not specific to individual dot paths. We suggest that these results could be accounted for in terms of a co-operative network in which mutual facilitation can propagate between detectors tuned to a common direction of motion
Radiation-induced root surface caries restored with glass-ionomer cement placed in conventional and ART cavity preparations: Results at two years
No full textThe document attached has been archived with permission from the Australian Dental Association (8th Jan 2008). An external link to the publisher’s copy is included.Background: There are no published studies comparing the clinical performances of more-viscous glass-ionomer cement (GIC) restorations when placed using conventional and atraumatic restorative treatment (ART) cavity preparation methods to restore root surface caries. Methods: One dentist used encapsulated Fuji IX GP and Ketac-Molar to restore 72 conventional and 74 ART cavity preparations for 15 patients who had received cervicofacial radiation therapy. Two assessors evaluated the restorations at six, 12, and 24 months for retention, marginal defects and surface wear, and recurrent caries. Results: After two years, the cumulative restoration successes were 65.2 per cent for the conventional and 66.2 per cent for the ART cavity preparations, without statistical or clinical significance (P>0.50). Restoration dislodgement accounted for 82.8 per cent and marginal defects for 17.2 per cent of all failures. There were no instances of unsatisfactory restoration wear or recurrent caries observed. Teeth with three or more restored cervical surfaces accounted for 79.3 per cent of all failures (P<0.0001). Conclusions: For root surface caries restored with GIC, the use of hand instruments only with the ART method was an equally effective alternative to conventional rotary instrumentation for cavity preparation. Larger restorations had higher failures, usually from dislodgement.JY Hu, XC Chen, YQ Li, RJ Smales and KH Yi
Paediatric use of melatonin (Author reply to D. J. Kennaway).
No full textComment on
Paediatric use of melatonin. [Eur J Paediatr Neurol. 2015]
Current role of melatonin in pediatric neurology: clinical recommendations. [Eur J Paediatr Neurol. 2015
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