1,002 research outputs found
Mamma Won\u27t Let Me Marry
No full textWoman lamenting that her mother will not let her marry until she turns 21https://egrove.olemiss.edu/kgbsides_uk/1477/thumbnail.jp
Diagnostic accuracy of lung ultrasound in diagnosis of ARDS and identification of focal or non-focal ARDS subphenotypes: a systematic review and meta-analysis
No full textBackgroundAcute respiratory distress syndrome (ARDS) is a life-threatening respiratory condition with high mortality rates, accounting for 10% of all intensive care unit admissions. Lung ultrasound (LUS) as diagnostic tool for acute respiratory failure has garnered widespread recognition and was recently incorporated into the updated definitions of ARDS. This raised the hypothesis that LUS is a reliable method for diagnosing ARDS.ObjectivesWe aimed to establish the accuracy of LUS for ARDS diagnosis and classification of focal versus non-focal ARDS subphenotypes.MethodsThis systematic review and meta-analysis used a systematic search strategy, which was applied to PubMed, EMBASE and cochrane databases. Studies investigating the diagnostic accuracy of LUS compared to thoracic CT or chest radiography (CXR) in ARDS diagnosis or focal versus non-focal subphenotypes in adult patients were included. Quality of studies was evaluated using the QUADAS-2 tool. Statistical analyses were performed using "Mada" in Rstudio, version 4.0.3. Sensitivity and specificity with 95% confidence interval of each separate study were summarized in a Forest plot.ResultsThe search resulted in 2648 unique records. After selection, 11 reports were included, involving 2075 patients and 598 ARDS cases (29%). Nine studies reported on ARDS diagnosis and two reported on focal versus non-focal ARDS subphenotypes classification. Meta-analysis showed a pooled sensitivity of 0.631 (95% CI 0.450-0.782) and pooled specificity of 0.942 (95% CI 0.856-0.978) of LUS for ARDS diagnosis. In two studies, LUS could accurately differentiate between focal versus non-focal ARDS subphenotypes. Insufficient data was available to perform a meta-analysis.ConclusionThis review confirms the hypothesis that LUS is a reliable method for diagnosing ARDS in adult patients. For the classification of focal or non-focal subphenotypes, LUS showed promising results, but more research is needed
Transvestism and capacity to marry
No full textThe article concerns the issue of transvestism and the influence of this paraphilia on the capacity to marry. The author focuses on four issues: gender identification, transvestism as a gender identity disorder, pesudotransvestism as a special form of the analyzed paraphilia and the relationship between transvestism and marriage invalidity. The article is a scientific synthesis of legal, jurisprudence, psychiatric and psychological approach to this problem
Understanding the decision to marry versus cohabit: the role of interpersonal dedication and constraints and the impact on life satisfaction
No full textThe current study explored men's and women's reasons for choosing to marry rather than to cohabit using a national data set (n = 786) of adults who were currently married or had been married previously. Using commitment theory participant's open-ended reasons for choosing to marry were coded into categories of either interpersonal dedication or constraint commitment. A variety of demographic, attitudinal, and relationship history variables were then used to predict commitment type. The influence of commitment type during the decision to marry on life satisfaction was also explored. Results indicate that current marital status (being married vs. being divorced or separated) and cohabiting before marriage were the strongest predictors of interpersonal dedication reasons for marriage for both men and women. Level of conventionality and parents' marital status also emerged as significant predictors of constraint commitment. Finally, marrying for reasons related to interpersonal dedication significantly predicted higher life satisfaction for men but not for women
Will I marry if my parents can\u27t? Young adults with LGB parents consider marriage for themselves
No full textAlthough an emerging body of research has examined lesbian, gay, and bisexual (LGB) adults\u27 attitudes and feelings about marriage, very little research has explored how their offspring view marriage. The current exploratory, qualitative, interview-based study of 35 adolescents and emerging adults (ages 15-28 years; mean age = 21 years) with LGB parents examines their attitudes about and desire for marriage. Results revealed that many participants endorsed romantic ideas about marriage and hoped to someday marry themselves. Other participants expected to marry, but solely for pragmatic reasons (i.e., legal/financial protections). Some participants expressed concerns about the institution of marriage, and therefore rejected marriage for themselves-although some conceded that they might marry if and when all LGB people were able to marry. Finally, a small group of participants expressed a desire to marry, but struggled with the idea of marrying when their LGB parents could not. These findings reveal great diversity in the marital desires of young adults with LGB parents, and highlight the various social contexts that ultimately shape their beliefs and intentions surrounding marriage. © The Author(s) 2013
Cathedral church of Assumptoin of the Blessed Virgin Marry a short historical draft (19th century)
No full textKościół katedralny pw. Wniebowzięcia Najświętszej Maryi Panny i Polonia w Charkowie: krótki szkic historyczny (XIX wiek). Autorka w przedstawionym artykule przybliża krótki zarys historii kościoła katedralnego pw. Wniebowzięcia Najświętszej Maryi Panny w Charkowie od czasu jego wzniesienia do chwili jego uroczystego poświęcenia 26 lipca 1892 roku przez biskupa pomocniczego diecezji mohylowskiej Franciszka Albina Simona. Budowa świątyni została ukazana na tle funkcjonowania w Charkowie w XIX wieku społeczności polskiej, która z niewielkiej garstki wiernych zdołała przekształcić się w niezwykle istotną część składową mieszkańców miasta. Ostoją dla działalności Polaków mieszkających w Charkowie był kościół katedralny pw. Wniebowzięcia Najświętszej Maryi Panny, który przetrwał do czasów obecnych, i dziś, jako perła architektury sakralnej, zdobi centrum miasta.Cathedral church of Assumptoin of the Blessed Virgin Marry a short historical draft (19th century). The author of the article presents a short outline of the cathedral church of Assumption of the Blessed Virgin Marry in Kharkiv since the moment it was built to its ceremonial cosercation in June 26, 1892 by the bishop of Molyhowska Diocese Albin Simon. Building of the church has been shown on the background of functioning of Polish community in Kharkiv in the 19th century which from a small group of believers managed transform into an important part of the citizens of the city. The cathedral church of Assumption of the Blessed Virgin Marry was a rock for Poles’ activities leaving in Kharkiv. The church survived till today and it adrous the city centre as an architectural jewel
Stress-strain curve and elastic behavior of the fibrotic lung with usual interstitial pneumonia pattern during protective mechanical ventilation
No full textBackground- Patients with acute exacerbation of lung fibrosis with usual interstitial pneumonia (EUIP) pattern are at increased risk for ventilator-induced lung injury (VILI) and mortality when exposed to mechanical ventilation (MV). Yet, lack of a mechanical model describing UIP-lung deformation during MV represents a research gap. Aim of this study was to develop a constitutive mathematical model for UIP-lung deformation during lung protective MV based on the stress-strain behavior and the specific elastance of patients with EUIP as compared to that of acute respiratory distress syndrome (ARDS) and healthy lung.
Methods- Partitioned lung and chest wall mechanics were assessed for patients with EUIP and primary ARDS (1:1 matched based on body mass index and PaO2/FiO2 ratio) during a PEEP trial performed within 24 h from intubation. Patient’s stress-strain curve and the lung specific elastance were computed and compared with those of healthy lungs, derived from literature. Respiratory mechanics were used to fit a novel mathematical model of the lung describing mechanical-inflation-induced lung parenchyma deformation, differentiating the contributions of elastin and collagen, the main components of lung extracellular matrix.
Results- Five patients with EUIP and 5 matched with primary ARDS were included and analyzed. Global strain was not different at low PEEP between the groups. Overall specific elastance was significantly higher in EUIP as compared to ARDS (28.9 [22.8 – 33.2] cmH2O versus 11.4 [10.3 – 14.6] cmH2O, respectively). Compared to ARDS and healthy lung, the stress/strain curve of EUIP showed a steeper increase, crossing the VILI threshold stress risk for strain values greater than 0.55. The contribution of elastin was prevalent at lower strains, while the contribution of collagen was prevalent at large strains. The stress/strain curve for collagen showed an upward shift passing from ARDS and healthy lungs to EUIP lungs.
Conclusions- During MV, patients with EUIP showed different respiratory mechanics, stress-strain curve and specific elastance as compared to ARDS patients and healthy subjects and may experience VILI even when protective MV is applied. According to our mathematical model of lung deformation during mechanical inflation, the elastic response of UIP-lung is peculiar and different from ARDS. Our data suggest that patients with EUIP experience VILI with ventilatory setting that are lung-protective for patients with ARDS
Quantitative CT-analysis of over aerated lung tissue and correlation with fibrosis extent in patients with idiopathic pulmonary fibrosis.
No full textINTRODUCTION- The usual interstitial pneumonia (UIP) pattern, hallmark of idiopathic pulmonary fibrosis (IPF), may induce harmful local overdistension during mechanical ventilation given the juxtaposition of different tissue elasticities. Mechanotransduction, linking mechanical stress and strain to molecular pro-fibrotic pathways, likely contributes to fibrosis progression. Understanding the mechanical forces and aeration patterns in the lungs of IPF patients is crucial for unraveling potential mechanisms of disease progression. Quantitative lung computed tomography (CT) can accurately assess the air content of lung regions, thus informing on zonal distension. This study aims to investigate radiological evidence of lung over aeration in spontaneously breathing UIP patients compared to healthy controls during maximal inspiration.
METHODS- Patients with IPF diagnosis referred to the Center for Rare Lung Diseases of the University Hospital of Modena (Italy) in the period 2020-2023 who underwent High Resolution Computed Tomography (HRCT) scans at residual volume (RV) and total lung capacity (TLC) using standardized protocols were retrospectively considered eligible. Patients with no signs of lung disease at HRCT performed with the same image acquisition protocol nor at pulmonary function test (PFTs) served as controls. Lung segmentation and quantitative analysis were performed using 3D Slicer software. Lung volumes were measured, and specific density thresholds defined over aerated and fibrotic regions. Comparison between over aerated lung at RV and TLC in the two groups and according to lung lobes was sought. Further, the correlation between aerated lung and the extent of fibrosis was assessed and compared at RV and TLC.
RESULTS- IPF patients (N=20) exhibited higher over aerated lung proportions than controls (N=15) both at RV and TLC (4.5% vs. 0.7%, p<0.0001 and 13.8% vs. 7%, p<0.0001 respectively). Over aeration increased significantly from RV to TLC in both groups, with no intergroup difference (p=0.67). Sensitivity analysis revealed significant variations in over aerated lung areas among lobes when passing from RV to TLC with no difference within lobes (p=0.28). Correlation between over aeration and fibrosis extent was moderate at RV (r=0.62, p<0.0001) and weak at TLC (r=0.27, p=0.01), being the two significantly different at interpolation analysis (p<0.0001).
CONCLUSIONS-This study provides the first evidence of radiological signs of lung over aeration in patients with UIP-pattern patients when passing from RV to TLC. These findings offer new insights into the complex interplay between mechanical forces, lung structure, and fibrosis and warrant larger and longitudinal investigations
Incest Statutes and the Fundamental Right of Marriage: Is Oedipus Free to Marry?
No full textThe U.S. Supreme Court has found that the right to marry is a constitutionally protected right. That right is restricted, however, by state incest statutes which impede marriage between adults by making some choices of a marriage partner illegal. The constitutional validity of modern state incest statutes is difficult to analyze because of shifting definitions, reflexive fears, ambivalent attitudes, and underlying facile generalizations.
The mere word incest triggers strong feelings of revulsion in most people. Therefore, any a priori labeling of a marriage as incestuous tends to preclude objective thought about the permissibility of the particular form of the marriage prohibition at issue. Such revulsion stems largely from the confusion of incest with sexual abuse of children. This confusion is not limited to the general public, but extends to the courts as well.
The incest motif itself persists as a tradition. Alleged public horror combined with obvious fascination for the theme extends in an unbroken line from the myths of preliterate peoples to contemporary literature. Any examination of contemporary incest statutes as a limitation on the right to marry must be sensitive to the historically ambivalent reactions to acts in contravention of the prohibition.
Finally, myths and half-truths about the genetic effects of incestuous matings on the offspring represent another impediment to an analysis of the constitutional validity of contemporary incest statutes as marriage prohibitions. Although directly contradicted by current scientific knowledge of genetic inheritance, common knowledge continues to teach that incestuous unions cause mentally and/or physically defective offspring.
Once one recognizes these analytical difficulties—reflexive fears, shifting definitions of incest itself, ambivalent attitudes, and facile underlying generalizations—one can begin to rationally evaluate the validity of state incest statutes in the light of the constitutional right to marry. After making such an analysis, this author has concluded that neither the civil marriage bar nor the criminal bar against incestuous acts serves any valid purpose which cannot be better served by statutes which do not impinge on the constitutional right to marry
Short Black Aprons and Dandy Caps
No full textA woman fears she is too old to marry and will marry the first one who asks.https://egrove.olemiss.edu/kgbsides_uk/1786/thumbnail.jp
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