5 research outputs found
Coronary Artery Pathology in Patients with Peri-implantitis // Патология на коронарните артерии при пациенти с периимплантит
No full textThe thesis is focused on investigating the relationship between peri-implantitis — an inflammatory condition of the peri-implant tissues accompanied by bone resorption — and pathological changes in the coronary arteries. The study aims to evaluate whether patients with peri-implantitis exhibit a higher prevalence and more severe forms of coronary artery disease. Additionally, a comparison was made between coronary artery pathology in patients with peri-implantitis and those with periodontitis. Using clinical and laboratory (paraclinical) methods, including coronary angiography, the degree of coronary atherosclerosis was assessed, along with its potential association with systemic inflammation associated with peri-implantitis. General health status, peri-implant tissue condition, and various laboratory markers were also analysed. The results provide new evidence for the role of oral health in the pathogenesis of cardiovascular diseases and emphasise the importance of a multidisciplinary approach in their prevention and treatment.Дисертационният труд е насочена към изследване на връзката между периимплантит – възпалително заболяване на периимплатните тъкани, съпроводено с костна резорбция и патологичните промени в коронарните артерии. Целта на проучването е да се оцени дали пациентите с периимплантит проявяват по-висока честота и по-тежки форми на коронарна артериална болест. Отделно е направено и сравнение патологията на коронарните артерии при пациенти с периимплантит и такива с пародонтит. Чрез прилагане на клинични и лабораторни (параклинични), включително ангиографско изследване, се анализира степента на коронарна атеросклероза и нейната евентуална зависимост от системното възпаление, предизвикано от периимплантита. Сравни се общото здравословно състояние, състоянието на периимплантните тъкани и редица лабораторни показатели. Резултатите предоставят нови доказателства за ролята на оралното здраве в патогенезата на сърдечносъдовите заболявания и да подчертаят значението на мултидисциплинарния подход в превенцията и лечението им
Periodontal disease etiology. A review
Full text linkPeriodontitis is a chronic inflammatory disease that is characterized by destruction of the tooth-supporting tissues, periodontal pocket formation, and ultimately, loss of teeth. The primary cause of periodontitis is bacteria in the dental biofilm. The development of effective treatment strategies is challenging due to the complex pathogenesis of the disease, which is best explained by a polymicrobial synergy and dysbiosis model
Peri-implantitis
Full text linkPeri-implantitis is a biological complication that can occur after a dental implant is placed. It encompasses inflammatory reactions around the implant, such as peri-implant mucositis and peri-implantitis itself. As dental implants become more widely used, complications associated with them are also becoming more common. Several risk factors can contribute to the development of peri-implantitis. These include placing an implant when there is an existing periodontal infection in the remaining teeth, as well as when there is inadequate width of attached gingiva. Poor oral hygiene is another significant risk factor. Additional factors include the presence of an endodontic infection near where the implant is placed, improper implant positioning in terms of prosthetic and/or biological alignment, the implant design itself, incorrect abutment choice, and unremoved cement in cement-retained prosthetic devices. Systemic and genetic factors can also play a role in modifying the risk of peri-implantitis. Peri-implant inflammatory diseases are diagnosed through both clinical and paraclinical testing methods. This involves assessing the risks associated with the implant, such as whether plaque is present, whether there is bleeding on probing, edema, erythema, increased probing depths, exudation, bone loss around the implant, and implant mobility. The treatment for peri-implant inflammation involves CIST therapy
Author Correction: Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing
Full text linkAn amendment to this paper has been published and can be accessed via a link at the top of the paper
