47 research outputs found
An overview of direct somatic reprogramming: The ins and outs of iPSCs
No full textStem cells are classified into embryonic stem cells and adult stem cells. An evolving alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs), which have a multi-lineage potential comparable to conventionally acquired embryonic stem cells with the additional benefits of being less immunoreactive and avoiding many of the ethical concerns raised with the use of embryonic material. The ability to generate iPSCs from somatic cells provides tremendous promise for regenerative medicine. The breakthrough of iPSCs has raised the possibility that patient-specific iPSCs can provide autologous cells for cell therapy without the concern for immune rejection. iPSCs are also relevant tools for modeling human diseases and drugs screening. However, there are still several hurdles to overcome before iPSCs can be used for translational purposes. Here, we review the recent advances in somatic reprogramming and the challenges that must be overcome to move this strategy closer to clinical application
Plastic Strain in Materials Under the Influence of Impulsive Load
No full textTitle: Plastic Strain in Materials Under the Influence of Impulsive Load, Author: Shailendra K. Sinha, Location: ThodeEquipment was designed for testing dynamic behaviors of materials subjected to impulsive load. Detail design of the equipment and experimental techniques have been described. Armco Ingot Iron with 99.8% purity was tested. Before testing, the material was fully annealled. "n" and "G(ε,t) (as occurring in the characteristic equation σm^n to K(n) = G (ε,t), for this material were evaluated. The material was found to ber very sensitive to strain rates.ThesisMaster of Engineering (ME
Evaluating effects of water quality BMPs on nitrate-nitrogen losses and crop yield at field and watershed scales
No full textSubmission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-12-01The student, Shailendra Singh, accepted the attached license on 2021-11-17 at 21:07.The student, Shailendra Singh, submitted this Dissertation for approval on 2021-11-17 at 22:57.This Dissertation was approved for publication on 2021-11-22 at 15:15.DSpace SAF Submission Ingestion Package generated from Vireo submission #17223 on 2022-04-06 at 17:16:53Made available in DSpace on 2022-04-29T21:45:55Z (GMT). No. of bitstreams: 3
SINGH-DISSERTATION-2021.pdf: 3978859 bytes, checksum: f4583c48d462a25b3307523d79ccc693 (MD5)
LICENSE.txt: 4213 bytes, checksum: dca24be3f7aa8f25869f3d0f75334f81 (MD5)
PROQUEST_LICENSE.txt: 4559 bytes, checksum: 2a4b70e3da8c695ee57ef22a18a76d28 (MD5)
Previous issue date: 2021-11-22Embargo set by: Seth Robbins for item 123333
Lift date: 2024-04-29T21:46:25Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 123333
Lift date: 2024-04-29T21:47:53Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I OnlyNitrate-nitrogen (NO3-N) transport from agricultural lands is a major source of surface water pollution in the Midwestern United States. The majority of highly productive agricultural lands in the Midwest region uses subsurface tile drainage to improve crop productivity. However, subsurface tile drainage provides preferential pathways that transfer contaminated water directly to surface water bodies without this water being subjected to soil processes that attenuate NO3-N concentrations. The purpose of this study was to evaluate the long-term impact of different in-field management practices on NO3-N losses and crop production at both field and watershed scales using water quality models. At first, we reviewed 20 years of modeling studies conducted using different field-scale models to assess the effect of various agricultural management practices on NO3-N losses and crop yield and the models' ability to quantify complex processes accurately. Based on our review, we determined two field-scale models: DRAINMOD-DSSAT and RZWM2, suit our research need.
We evaluated DRAINMOD-DSSAT using eight years of field observed data from randomly tile-drained, corn-soybean agricultural systems near Danville, central Illinois. The model performed well in simulating field water balance, N balance, and crop yield for both calibration and validation periods. The long-term model simulation results indicated that split N application of 50% during spring-pre plant (S) and 50% during side-dressing (SD) could increase crop yield and reduce N leaching losses compared to other tested N application methods: spring (S) only, fall-spring split (F-S), and fall-spring-side-dressing (F-S-SD). Further, applying 10% and 20% reduced N rates (194 kg N ha-1 and 174 kg N ha-1, respectively) in combination with S-SD split application in controlled drainage (CD) condition could reduce N leaching losses by 30% and 33%, respectively compared to the conventional application method. Further, we compared DRAINMOD-DSSAT and RZWQM2 to determine how accurately both models predict hydrology, NO3-N, and crop yield. Our model comparison results showed that both models could simulate field water balance, N balance, and crop yield satisfactorily. The long-term simulation comparison results showed that both the models provided the same conclusion on the effects of N management strategies on NO3-N losses and crop yield, but they differ in quantity.
We used RZWQM2 model to evaluate the combined effects of water quality best management practices (BMPs) on tile drainage NO3-N losses and crop yield in a continuous corn system. The model was calibrated and validated using observed data from the Dudley Smith Initiative (DSI) project research site located in Christian County, central Illinois. We calibrated and validated the RZWQM2 model satisfactorily and used it to evaluate long-term impacts of field implemented BMPs using 30-years historical weather data. Based on our long-term evaluation, we found that a 10% reduction in the current N application rate of 224 kg N ha-1 could reduce NO3-N losses by 25-32% without negatively impacting corn yield in 4R and cover crop+4R treatments compared to the conventional method, suggesting further room for N rate optimization. In addition, we scaled up DSI implemented management practices to quantify the impacts on water quality and crop yield at watershed scale using SWAT+ model. The model was calibrated and validated for Upper Sangamon River watershed in central Illinois using 14 years of climate, streamflow, riverine NO3-N, and county-level crop yield data. The model performance for calibration and validation periods ranged from good to very good. The long-term simulation over the period of 30-years showed a reduction of NO3-N load by up to 32% without impacting crop yield. The results suggest that reducing the current N application rate by 20% (i.e., from 224 kg N ha-1 to 179 kg N ha-1) and using 40:60 split N application between spring pre-plant and side-dressing combined with cereal rye as a cover crop in corn-soybean rotation can significantly benefit in minimizing NO3-N losses without losing crop production goals. This study will help researchers and stakeholders in making agricultural decisions beneficial in off-setting environmental impacts and achieving production goals
An experimental and theoretical investigation on torrefaction of a large wet wood particle
No full textCharacterization of hydrothermally synthesized SnS nanoparticles for solar cell application
No full textLow Temperature Drying of Foods
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Enhancement in light harvesting ability of photoactive layer P3HT: PCBM using CuO nanoparticles
No full textLow Temperature Drying of Basil
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
PEDOT: PSS: rGO nanocomposite as a hole transport layer (HTLs) for P3HT:PCBM based organic solar cells
No full text
