388 research outputs found

    Data for water activity for Terra Sirenum salt combinations

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    <p>Water activity values for various salt combinations based on Terra Sirenum mineralogy.</p&gt

    Supplemental Material - Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review

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    Supplemental Material for Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review by Harsh Priya, Manali Deb Barma, Bharathi M Purohit, Deepali Agarwal, Upendra Singh Bhadauria, Nitesh Tewari, Shalini Gupta, Deepika Mishra, Rahul Morankar, Vijay Prakash Mathur and Ritu Duggal in Tobacco Use Insights</p

    Supplemental Material - Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review

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    Supplemental Material for Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review by Harsh Priya, Manali Deb Barma, Bharathi M Purohit, Deepali Agarwal, Upendra Singh Bhadauria, Nitesh Tewari, Shalini Gupta, Deepika Mishra, Rahul Morankar, Vijay Prakash Mathur and Ritu Duggal in Tobacco Use Insights</p

    ICTs and rural development in India

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    This monograph compares the methodologies and progress of the different existing models of information and communication technology (ICT) use for broad-based development and economic growth in India. It will examine the role of complementary reforms in government administration and policies. The focus is chiefly on the rural economy, where the developmental needs are the greatest, and the use of ICTs presents the most challenges. It examines the nature of benefits in areas such as education, health, market efficiency, and democratic participation, the channels through which impacts can be realized, and the practical means for realizing potential benefits, including organizational innovations and government policy as well as structural changesIndia; ICTs; Internet; development

    THE PASSAGE: Enquiry into the Ephemeral Absence of Social Construct During Transitions

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    “In the universe, there are things that are known, and things that are unknown, and in between them, there are doors.” ― William Blake. This thesis support paper presents my artistic research on the ephemeral nature of absence in social constructs while relocating myself to new places. I am interrogating a fluid positionality that is continuously shifting, leading me to contextualise the research stance in the between and betwixt of Passage. I am examining the experience of passing from one place, condition, or stage to another and highlight the in-between space made visible through artwork produced with various methods and processes. Throughout, absence is indicated via aesthetics, materiality, and immateriality pointing to subtle boundaries between play and seriousness, the real and imaginary, the ephemeral and permanent. Themes of travel, constraint, absence, liminality, and human consciousness are explored through performative installations, architectural spaces, and different degrees of audience participation. The research generates a dialogue between performance, space, and time which involves bodily experience, live actions with mixed media installations, and time-based works. The choice of media and symbols revolve around various conceptual ideas inspired by academic and non-academic sources — contemporary art, spiritual texts, psychology, lucid visions while meditating — which become the artistic expression's metaphorical core. Anchoring in an auto-ethnographic methodology of resisting mastery, the research was conducted by allowing space for unknowns to reveal their contours through silent being and doing by not doing

    India’s Development Strategy: Accidents, Design and Replicability

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    This paper examines India’s development strategy, and to what extent it may be considered a success. It provides a brief history of why and how the strategy was adopted, as well as of its implementation, including the role of initial conditions, such as human capital, geographical location, and infrastructure. It analyzes the extent and reasons for success of the strategy, including policy, political economy, timing, and linkage of the strategy to economy-wide development. Particular attention is given to the relative roles of domestic and international actors, including the part played by foreign investment, trade, and other dimensions of openness. The paper considers the extent to which the strategy remain viable for the future, the challenges still faced, and what other strategies might be required. It concludes with possible lessons for other countries and their future development strategies.development strategy, industrial policy, political economy, economic development

    CRISPR/Cas13: A Novel and Emerging Tool for RNA Editing in Plants

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    Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein (Cas) act as an adaptive immune system against invading nucleic acids and bacteriophages in bacteria and archaea. Based on the constitution of effector protein, CRISPR/Cas is broadly divided into multiple types and subtypes. Among these, type VI CRISPR/Cas system is of special attention with four subtypes, namely, VI-A, VI-B, VI-C, and VI-D, and are believed to have evolutionary origin from transposons. These subtypes exhibit variations in structural architecture and mechanism and have diverse Cas13a (C2c2), Cas13b1 (C2c6), Cas13b2 (C2c6), Cas13c (C2c7) and Cas13d effector proteins. CRISPR/Cas13 ribonuclease processes pre-crRNA to mature crRNA which targets and knockdown single-stranded RNA of phage genome during viral interference. The high specificity RNA guiding and RNA-targeting capacity of this protein enables to fuse with several effector molecules, opening new avenues in the field of Cas13-mediated RNA targeting, tracking, and editing. CRISPR/Cas13 has a unique feature of targeting RNAs including plants, so it can be used as a new tool for engineering interference against plant pathogens including RNA viruses, with better specificity and for other RNA modifications in plants. Fluorescent probe-tagged deactivated programmable Cas13 proteins could be used as an alternative tool for in vitro RNA studies. The engineered Cas13 can also be used for programmable RNA editing. The high target specificity, low cost, and user-friendly operation of CRISPR/Cas13 make this an effective tool for several RNA-based research studies and applications. Therefore, the focus of this chapter is upon classification of CRISPR/Cas system, structural and functional diversity of type VI CRISPR/Cas system including its discovery and origin, mechanism, and role of Cas13 in RNA editing of plants

    Selection between aztreonam and cephalosporins for treatment of infections with pseudomonads needs more caution

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    Bhoj R Singh Division of Epidemiology, ICAR-Indian Veterinary Research Institute, Izatnagar, IndiaIn the recently published study1 to evaluate the use of aztreonam as an active empiric&nbsp;therapy against subsequent culture of Pseudomonas aeruginosa, empiric therapy failure&nbsp;using aztreonam is reported more common than on using &beta;-lactam antibiotics in&nbsp;patients suffering P. aeruginosa infection. Though the study is interesting and revealing&nbsp;important findings regarding antibiotic use for treatment of P. aeruginosa infection, it&nbsp;should be accepted with caution as suggested by the authors1 repeatedly due to limited&nbsp;number of cases. In our observations on P. aeruginosa (95) and other pseudomonads&nbsp;(40) isolates from veterinary clinical cases we found that instead of generalizing the&nbsp;lesser efficacy of aztreonam in-depth studies are required. Although insignificant,&nbsp;aztreonam inhibited more numbers of extended spectrum &beta;-lactamase (ESBL) producing&nbsp;(57) P. aeruginosa strains (56.1%) than most of the &beta;-lactams including cefotaxime,&nbsp;ceftriaxone and piperacillin (53.3%). However, on non-ESBL producing (37) strains&nbsp;aztreonam inhibited 42.1% isolates, much less than cefepime (68%), ceftriaxone (50%)&nbsp;and piperacillin + tazobactam (61.1%). Therefore, it is suggested to use the two classes&nbsp;of antibiotics (aztreonam and &beta;-lactams) judiciously based on antibiotic stewardship&nbsp;principle1 instead of following some general rule for infections with pseudomonads. Authors&rsquo; reply Michael Hogan,1 Mary Barna Bridgeman,1 Gee Hee Min,1 Deepali Dixit,1 Patrick J Bridgeman,1 Navaneeth Narayanan1,21Department of Pharmacy Practice and Administration, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA; 2Division of Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA We appreciate the author of this letter reading our article with such great interest. We believe, however, in this response that&nbsp;here is limited application to the context and overall content&nbsp;of our clinical study of human patients. First, the data cited&nbsp;n this response are from veterinary clinical cases. Though&nbsp;general principles of understanding of antibiotic sensitivity&nbsp;testing and resistance mechanisms apply regardless of&nbsp;species, there are major differences that impede reasonable&nbsp;comparisons between the assertions in this letter and findings&nbsp;of our original study. View the original paper by Hogan and colleague
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