1,720,982 research outputs found
Thymoma with an incidental benign laryngeal mass mimicking laryngeal carcinoma: Case report
No full textSIMSEK, GOKCE/0000-0001-5281-0986Thymic carcinomas are rarely seen. Because of recurrent laryngeal nerve involvement, hoarseness is a common presenting symptom. Persistent hoarseness in a male smoker past his fifth decade is also a distinctive symptom for laryngeal carcinoma. Stroboscopic laryngeal examination and biopsy are required for the diagnosis. In this article we describe a case involving a patient with thymic carcinoma who, interestingly, also presented with a benign laryngeal mass with unilateral vocal fold fixation. We emphasize the importance of keeping in mind nonlaryngeal pathologies invading the recurrent laryngeal nerve in patients with persistent hoarseness and a nonspesific laryngeal mass
Early Paper Patching Versus Observation in Patients With Traumatic Eardrum Perforations: Comparisons of Anatomical and Functional Outcomes
No full textSIMSEK, GOKCE/0000-0001-5281-0986The purpose of this study was to compare the outcomes of patients with acute tympanic membrane perforation after spontaneous healing and paper-patching procedure. Methods: Design, Setting, and Participants: In this study, we performed a retrospective chart review with a prospective follow-up in 63 patients with tympanic membrane perforations. The patients undergoing a paper-patching procedure were assigned to group 1 (n = 33), whereas the patients that healed spontaneously were included in group 2 (n = 30). Retrospective analyses of the otoscopic examination findings and audiometric test results of the groups at the sixth-week follow-up were compared. Results: Eardrum healing was achieved in 90.9% of the patients in group 1 and 76.7% of the patients in group 2 at the sixth week (P > 0.05). The mean values of air conduction were significantly improved, and the air-bone gap was markedly decreased in the patients treated with paper patching, when compared with the patients in group 2 (P < 0.001). The area of perforation was found to be inversely related to the healing success. Conclusions: Early intervention by paper patching, which is a readily applicable procedure, may be offered to the patients with acute perforation of the tympanic membrane, because of the slightly better closure rates and significantly higher hearing functions when compared with simple observation
Comparison of Surgical Outcomes and Patient Satisfaction After 2 Different Rhinoplasty Techniques
No full textSIMSEK, GOKCE/0000-0001-5281-0986Various methods of surgical treatment are defined in nasal deformities that cause nasal obstruction. Open technique septorhinoplasty is a method that is frequently used for this purpose. This study aims to compare surgical results of open technique septorhinoplasty operations with and without osteotomies. In addition, changes in the quality of life of patients before and after treatment were investigated, and the effects of the 2 methods on patients' quality of life were compared. Methods: Patients with nasal deformity were included in the study. Forty patients with wide nasal dorsum and a prominent hump underwent septorhinoplasty with lateral osteotomy (group 1), and 35 patients with a narrow nasal dorsum and a minimal hump underwent septorhinoplasty without osteotomy (group 2). A Nasal Obstruction Symptom Evaluation (NOSE) questionnaire was used to evaluate disease-specific quality of life for patients in both groups. Basic characteristics, operative parameters, and preoperative and postoperative NOSE scores were compared between the groups. Results: Demographic properties of the groups were similar. Intraoperative parameters and postoperative complications were not different between the groups, with the exception of operation time (which was significantly longer in group 1) and ecchymosis (which was seen in whole cases of group 1 and none of the group 2). Preoperative NOSE scores were similar in both groups. Postoperative NOSE scores were 5 (0-45) in group 1 and 10 (0-45) in group 2 (P > 0.05). The NOSE scores were significantly decreased after the operation in both groups (P < 0.001). The 2 groups were not significantly different when comparing the change in preoperative and postoperative NOSE scores. Conclusions: Rhinoplasty with or without osteotomy is an effective treatment for alleviating nasal obstruction symptoms. Osteotomy is an integral but not obligatory part of the operation. The addition of the osteotomy procedure in selected cases prolonged the operation time and significantly enhanced patient satisfaction
Transposition of lingual thyroid gland to the submandibular region by transoral approach
No full textSIMSEK, GOKCE/0000-0001-5281-0986The purpose of this case report is to demonstrate surgical technique of only functional but symptomatic lingual thyroid gland transposition to submandibular region by transoral approach without mandibulotomy and tongue-splitting. A 37-year-old female patient was admitted to our hospital with dysphagia and apnea symptoms. Physical examination revealed 3 cm x 3 cm lingual thyroid gland was detected at the tongue base. The patient was euthyroid and thyroid gland was not detected in the neck. Under general anesthesia, right submandibular gland excision and transposition of lingual thyroid tissue to submandibular region with dorsal lingual artery axis flap were performed by transoral approach. Thyroid hormones remained normal in the postoperative period. In conclusion transoral transposition of lingual thyroid to submandibular region as a flap without mandibulotomy is a minimally invasive and function preserving alternative approach. Besides preserving thyroid functions, this transoral surgical technique can be preferred by patients who avoid skin incision for esthetic concerns. (C) 2016 Elsevier Ireland Ltd. All rights reserved
Mean Platelet Volume Decreases in Adult Patients With Obstructive Sleep Apnea After Uvulopalatal Flap Surgery
No full textSIMSEK, GOKCE/0000-0001-5281-0986Aim:The main purpose of the study was to investigate changes in mean platelet volume (MPV) values in patients with obstructive sleep apnea syndrome (OSAS) who had undergone uvulopalatal flap (UPF) surgery.Method:The study included a review of the medical records of 37 adult patients who had undergone UPF surgery after being diagnosed with OSAS. The baseline blood parameters of patients, including the MPV and platelet distribution width (PDW) values, were measured and repeated 3 months after treatment. Polysomnographic evaluations of the patients were also performed during admission and the 3rd month control. Comparisons of MPV values and their correlation with polysomnographic parameters were the main outcomes measured.Results:The blood parameters of all patients were similar except for MPV values, which were significantly lower after treatment (P0.05).Conclusion:The UPF surgery, which is a relatively simple surgical intervention to treat OSAS, alleviates nocturnal hypoxic episodes and lowers platelet volume. These may both be important predictors of adverse cardiovascular outcomes related to OSAS
Topical Application of Arnica and Mucopolysaccharide Polysulfate Attenuates Periorbital Edema and Ecchymosis in Open Rhinoplasty: A Randomized Controlled Clinical Study
No full textSIMSEK, GOKCE/0000-0001-5281-0986Background: The purpose of this study was to investigate the effects of local arnica and mucopolysaccharide polysulfate treatment on the regression of postoperative edema and ecchymosis in patients who have undergone open technique rhinoplasty. Method: One hundred eight patients were included in the study. Participants were randomized into three groups, all of whom had undergone rhinoplasty. Group 1 (n = 36) received postoperative arnica cream treatment, and group 2 (n = 36) received postoperative mucopolysaccharide polysulfate cream treatment. Group 3 (n = 36, control group) consisted of patients who received no postoperative local treatments. Patients were evaluated for 24 hours on days 2, 5, 7, and 10 after the operation. For the evaluation of postoperative edema and ecchymosis, a scale ranging from 0 to 4 was used, and the groups were compared. Results: In groups 1 and 2, postoperative ecchymosis was significantly less than in the control group during postoperative days 1, 5, and 7 (p 0.005). Conclusions: The authors' results suggest that a rapid regression of edema and ecchymosis may be achieved by local treatments of arnica and mucopolysaccharide polysulfate cream. In addition, there are no significant differences between these two treatment regimens. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II
The Effect of Passive and Active Smoking on Nasal Mucociliary Clerarance Time
No full textSIMSEK, GOKCE/0000-0001-5281-0986Aim: The aim of this study was to investigate the effect of passive and active smoking on NMC by comparing the results of age and sex matched healthy individuals, passive and active smokers. Material and Method: A total of 75 subjects met the criteria and were divided into three groups: control group (nonsmokers, group 1, n = 25), passive smokers group(group 2, n = 25), active smokers group (group 3, n = 25). NMC of these subjects were measured and compared. Moreover, the amount of cigarette consumption of active smokers group were calculated as package to year and the correlation between NMC and the amount of cigarette consumption. in active smokers group were evaluated. Results: The mean NMC in passive smokers group and active smokers group were significantly longer than the control group (p= 0,0001) The comparison of NMC values between the passive smokers group and the active smokers group revealed no statistically significant differences (p >= 0,05). There was positive correlation between the increase in NMC and amount of cigarette consumption in the active smokers group (p= 0,0001, r= 0.433). Discussion: Both active and passive smoking prolonged nasal mucociliary clearance time when they were compared with healthy controls. Tobacco exposure is associated diseases such as asthma, chronic rhinosinusitis, and lower airway infections. It may be related to the direct effect of prolonged NMC
Magnetic resonance imaging and computed tomography for diagnosing semicircular canal dehiscence
No full textINAL, MIKAIL/0000-0003-0642-7913; SIMSEK, GOKCE/0000-0001-5281-0986Objectives: We investigated the semicircular canal (SC) dehiscence using temporal computed tomography (CT) and magnetic resonance (MR) imaging. Methods: We retrospectively reviewed 114 (228 ears) consecutive MR images and CT scans of the temporal bones for dehiscence of the SCs. In the 1.5 Tesla (T) MR imaging, T1 and T2-weighted images were obtained. Dehiscence of the SCs was defined by absence of high attenuation bone coverage on the CT scans, and absence of low-signal bone margins on the MR images. Results: Superior SC dehiscence was detected in 4 (1.8%) ears using CT scans and 5 (2.2%) ears using MR imaging. Posterior SC dehiscence was detected in 4 (1.8%) ears using CT scans and 4 (1.8%) ears using MR imaging. In the non-dehiscent cases, there was hypointense bone coverage between the canal and the cerebrospinal fluid (CSF). However, in the cases of semicircular canal dehiscence, hypointense bone tissue did not appear between the canal and the CSF in the MR imaging. Conclusion: If there is clinical doubt about the presence of SC dehiscence, we recommend that MR imaging be conducted first. When dehiscence is not seen in the MR, a CT examination should be performed. MR imaging is preferred primarily, because it does not contain ionizing radiation. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved
Marked changes in olfactory perception during early pregnancy: a prospective case-control study
No full textSIMSEK, GOKCE/0000-0001-5281-0986Pregnancy seems to be related with a significant change in olfaction. Here, we investigate this theory by testing the odor identification abilities of uncomplicated pregnant women and compare the results with non-pregnant controls. The study included 31 healthy pregnant women in the first trimester (Group 1), 30 in the second trimester (Group 2), 31 in the third trimester, and 30 non-pregnant healthy controls (Group 4). In order to measure odor identification abilities, each subject completed the 12-item Brief Smell Identification Test (BSIT). Next, the demographic characteristics and BSIT scores of the groups were compared. The total BSIT scores of the subjects in Group 1 were found to be significantly lower than those of the other groups (p 0.05). Early pregnancy might be related to significant changes in olfactory performance. The distortion of odor identification in the first trimester might be a causative factor for the development of pregnancy-specific conditions, such as morning sickness and hyperemesis gravidarum, which are both common complaints during the early phase of parturition
Blood Parameters as Indicators of Upper Airway Obstruction in Children With Adenoid or Adenotonsillar Hypertrophy
No full textSIMSEK, GOKCE/0000-0001-5281-0986Adenotonsillar hypertrophy (ATH) is the most common cause of obstructive sleep apnea in children. This study aimed to evaluate the blood parameters of children with ATH who underwent surgery. Methods: The study included a review of the medical records of 130 children who underwent adenoidectomy or adenotonsillectomy with a diagnosis of adenoid hypertrophy and/or chronic tonsillitis. Patients were classified into 3 groups: group 1 (n = 69) underwent adenoidectomy, group 2 (n = 61) underwent adenotonsillectomy, and group 3 consisted of 82 healthy children. White blood cell count, platelet count, hemoglobin levels, mean platelet volume, and platelet distribution width values were the primary outcome measures. Results: Mean platelet volume, platelet distribution width and hemoglobin values decreased in the groups that underwent surgery. Whereas the decrease in group 1 was insignificant, it was significant in group 2. White blood cell count values increased in both group 1 (adenoidectomy) and group 2 (adenotonsillectomy), but the increase in group 2 was significant. No significant difference in platelet count was detected before versus after the operation. Conclusions: Upper airway obstruction caused by ATH remarkably changes the blood parameters related to chronic hypoxia. Significant improvement can be achieved after adenotonsillectomy rather than adenoidectomy alone
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