3,499 research outputs found
Decellularization as a method to generate a new generation of vascular grafts
Decellularization of blood vessels is a technique to remove cells from the extracellular matrix (ECM), which can be used as a vascular graft for peripheral or coronary blood vessel bypass surgery. This thesis focuses on the optimization of decellularization strategies for blood vessels such as porcine vena cava, to determine the optimal decellularization protocol (Paper I) and the ideal method of applying liquids during the decellularization process (Paper II). Our optimized strategy for blood vessel decellularization, which removes all cells from the ECM but leaves the mechanical properties and ultrastructure of the ECM intact, employs the detergents TritonX-100 and Tri-n-butyl phosphate in combination with the enzyme DNase, applied either by agitation or perfusion at low velocities. To test the utility of the decellularized vascular grafts, a preclinical animal study was performed by transplanting vena cava grafts in a pig animal model (Paper III). This study utilized decellularized blood vessels that were reconditioned with whole peripheral blood before transplantation. The results showed that blood vessels remained patent, resisted mechanical pressure and did not lead to a major immunogenic response. Taken together, this thesis describes a promising technique to generate novel vascular grafts based on decellularization on reconditioning of the ECM
Happy Hour with Robin Sacks
Robin Sacks is the author of Get Off My Bus!: How to Get Clarity, Get in the Driver\u27s Seat, and Get Moving in Your Life! Introduction by Kristen Kuhlman, LSW, LHNA, MBA/HCM DHA Candidate
Public management : Reinventing Government: a symposium. by Robin Butler
tag=1 data=Public management : Reinventing Government: a symposium. by Robin Butler
tag=2 data=Butler, Robin
tag=3 data=Public Administration,
tag=4 data=72
tag=5 data=2
tag=6 data=Summer 1994
tag=7 data=263-270.
tag=8 data=MANAGEMENT%PUBLIC SERVICE
tag=10 data=The author indicates how the major themes of the book [Reinventing Government] can be seen to correspond with many of the recent management initiatives in UK government.
tag=11 data=1994/6/8
tag=12 data=94/0490
tag=13 data=CABThe author indicates how the major themes of the book [Reinventing Government] can be seen to correspond with many of the recent management initiatives in UK government
Robin Becker, 16th Annual ODU Literary Festival
Robin Becker is the author of Giacometti’s Dog, published in 1990 by the University of Pittsburgh Press. Her previous books are Backtalk and Personal Effects, both published by Alice James Books She has received fellowships in poetry from the Massachusetts Artists Foundation and the National Endowment for the Arts. Her poems appear in many journals including Agni, The American Poetry Review, The Kenyon Review, and Ploughshares. She has published book reviews in Belles Lettres, The Boston Globe, The Boston Review, Prairie Schooner and The Women’s Review of Books She teaches in the Program in Writing and Humanistic Studies at Massachusetts Institute of Technology. This year she is Visiting Poet at Pennsylvania State University. Robin Becker serves as Poetry Editor for The Women’s Review of Books and as a member of the board of directors of Associated Writing Programs
Author Robin Silbergleid reads from her memoir "Texas girl," and her soon to be published book of poetry, "The baby book" at the Michigan Writers Series
Author Robin Silbergleid reads from her memoir "Texas girl," and her soon to be published book of poetry, "The Baby Book." Introductory remarks are provided by MSU Professor Telaina Eriksen and MSU Librarian Michael Rodriguez. Part of the MSU Libraries' Michigan Writers Series. Held at the MSU Main Library and sponsored by the MSU Department of English and the Center for Gender in Global Context
Writer Robin Lippincott reads from novel In the Meantime
Includes descriptive metadata provided by producer in MP3 file: "Listen to writer Robin Lippincott read from his new novel In the Meantime, which tracks the intertwined lives of three friends for six decades. Lippincott is also the author of Mr. Dalloway. The reading was part of the Gertrude Vanderbilt and Harold S. Vanderbilt Visiting Writers Program at Vanderbilt University. It was recorded on Oct. 31, 2007.
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