58,597 research outputs found
Marriage record of Simpson, Clarence L. and Brown, Anna D.
No full textMarriage license for Clarence L. Simpson and Anna D. Brown. J.L. Jones was the officiant
Port Argostoli
No full textsurveyed by lieutenant C. H. Simpson, r.n. assisted by lieut. J. C. Tancred & L. D. Penfold and sub-lieut. H. G. C. Somerville & E. A. Constable, r.n
Aristotle, Politics. Translated, with introduction and notes, by C. D. C. Reeve Aristotle, The Politics. Translated, with introduction, analysis and notes, by Peter L. Philipps Simpson Peter L. Philipps Simpson, A philosophical commentary on the "Politics" of Aristotle
No full textDestrée Pierre. Aristotle, Politics. Translated, with introduction and notes, by C. D. C. Reeve Aristotle, The Politics. Translated, with introduction, analysis and notes, by Peter L. Philipps Simpson Peter L. Philipps Simpson, A philosophical commentary on the "Politics" of Aristotle. In: Revue Philosophique de Louvain. Quatrième série, tome 102, n°1, 2004. pp. 163-165
Aristotle, Politics. Translated, with introduction and notes, by C. D. C. Reeve Aristotle, The Politics. Translated, with introduction, analysis and notes, by Peter L. Philipps Simpson Peter L. Philipps Simpson, A philosophical commentary on the "Politics" of Aristotle
No full textDestrée Pierre. Aristotle, Politics. Translated, with introduction and notes, by C. D. C. Reeve Aristotle, The Politics. Translated, with introduction, analysis and notes, by Peter L. Philipps Simpson Peter L. Philipps Simpson, A philosophical commentary on the "Politics" of Aristotle. In: Revue Philosophique de Louvain. Quatrième série, tome 102, n°1, 2004. pp. 163-165
Local factor production by MG63 osteoblast-like cells in response to surface roughness and 1,25-(OH)(2)D-3 is mediated via protein kinase C- and protein kinase A-dependent pathways
No full textTitanium (Ti) surface roughness affects bone formation in vivo and osteoblast attachment, proliferation and differentiation in vitro. MG63 cells exhibit decreased proliferation and increased differentiation when cultured on rough Ti surfaces (R-a > 2 mum) and response to 1,25-(OH)(2)D-3 is enhanced, resulting in synergistic increases in TGF-beta1 and PGE(2). To examine the hypothesis that surface roughness and 1,25-(OH)(2)D-3 exert their effects on local factor production through independent, but convergent, signaling pathways, MG63 cells were cultured on tissue culture plastic or on smooth (PT, R-a = 0.60 mum) and rough (SLA, R-a = 3.97 mum; TPS, R-a = 5.21 mum) Ti disks. At confluence (5 days), cultures were treated for 24h with 10(-8)M 1 alpha ,25-(OH)(2)D-3 and active and latent TGF-beta1 in the conditioned media measured by ELISA. Cell layers were digested with plasmin and released TGF-beta1 was also measured. 1,25-(OH)(2)D-3 regulated the distribution of TGF-beta1 between the media and the matrix in a surface-dependent manner; the effect was greatest in the matrix of cells cultured on SLA and TPS. Inhibition of PKA with H8 for the last 24h of culture increased PGE(2) on SLA and TPS, but when present throughout the entire culture period H8 caused an increase in PGE(2) on all surfaces. 1,25-(OH)(2)D-3 reduced the effect of H8 on PGE(2) production in cultures treated for 24 h. H8 had no effect on TGF-beta1 in the media by itself but caused a complete inhibition of the 1,25-(OH)(2)D-3 dependent increase. Inhibition of PKC with chelerythrine increased PGE(2) in a surface-dependent manner and 1,25-(OH)(2)D-3 reduced the effect of the PKC inhibitor. Chelerythrine also increased TGF-beta1 but the effect was not surface dependent; however, 1,25-(OH)(2)D-3 reduced the effects of chelerythrine with the greatest effects on the smooth surface. Thus, the distribution of TGF-beta1 between the media and the matrix is regulated by 1,25-(OH)(2)D-3 in a surface-dependent manner. Surface roughness exerts its effects on TGF-beta1 production via PKC but not PKA. The effect of 1,25-(OH)(2)D-3 on TGF-beta1 production is not via PKC. PKA is involved in the surface-dependent regulation of PGE(2) but not in the regulation of PGE(2) by 1,25-(OH)(2)D-3 on rough surfaces. Regulation of PKC affects PGE(2) production but it is not involved in the surface roughness dependent response to 1,25-(OH)(2)D-3. These results suggest two independent but interconnected pathways are involved. (C) 2001 Elsevier Science Ltd. All rights reserved.NIDCR NIH HHS [DE-05937, DE-08603
sj-docx-1-jiv-10.1177_08862605221147069 – Supplemental material for Unpacking Multiagency Structured Professional Judgment Risk Assessments for Family Violence
No full textSupplemental material, sj-docx-1-jiv-10.1177_08862605221147069 for Unpacking Multiagency Structured Professional Judgment Risk Assessments for Family Violence by Apriel D. Jolliffe Simpson, Chaitanya Joshi and Devon L. L. Polaschek in Journal of Interpersonal Violence</p
Data for Envelope Frequency Following Responses to Filtered Word Stimuli
No full textRaw EEG data in .bdf format, collected using a 32-channel ActiveTwo EEG system (BioSemi, the Netherlands). EEG data were measured during presentation of words at an intensity of 70 dB SPL LA eq using ER-2 insert earphones. Words are filtered in different band (0-500 Hz, 0-1000 Hz, 1000-end Hz and 2000-end Hz), with end being 8000 Hz as words were recorded at a sampling rate of 16000 Hz. Stimuli were 3 words presented randomly with an inter-stimulus interval of 1s. Data are published in according with the EPSRC guidelines for data sharing.
Data Supports the paper Vanheusden, F. J., Chesnaye, M. A., Simpson, D. M., & Bell, S. L. (2019). Envelope frequency following responses are stronger for high-pass than low-pass filtered vowels. International Journal of Audiology, 1-9. DOI: 10.1080/14992027.2018.1562243
This dataset, approx 28GB, is available on request via the webform at https://library.soton.ac.uk/datarequest</span
University research and the location of business R&D
No full textWe investigate the relationship between the location of private sector R&D labs and university research departments in Great Britain. We combine establishment-level data on
R&D activity with information on levels and changes in research quality from the Research Assessment Exercise. The strongest evidence for co-location is for pharmaceuticals R&D, which is disproportionately located near to relevant university research, particularly 5 or 5* rated chemistry departments. This relationship is stronger for foreign-owned labs, consistent with multinationals sourcing technology internationally. We also find some evidence for co-location with lower rated research departments in industries such as
machinery and communications equipment
Methane emissions from wetlands in the zone of discontinuous permafrost: Fort Simpson, Northwest Territories, Canada
No full textWe examined the influence of water table position, temperature, vegetation, and CH4 storage on CH4 flux at 22 wetland sites located in the zone of discontinuous permafrost, near Fort Simpson, Northwest Territories. Sites ranged from frozen peat plateaux and palsas with collapse scars to fens and bogs and ponds. Mean summer CH4 emissions ranged from −1.3 to 255 mg m−2 d−1, and the variation among sites was best explained by mean water table position (r2 = 0.62, n = 19). Large CH4 fluxes (>30 mg m−2 d−1) and high water tables occurred in ponds and graminoid sites, whereas small fluxes (<30 mg m−2 d−1) and low water tables occur in shrub and woody sites. These relationships were upheld across several northern boreal regions, based on water table depth and broad ecological criteria. CH4 turnover times were generated by comparing surficial fluxes and storage within the saturated portion of the peat profile. Graminoid sites had CH4 turnover times from 1 to 4 days, whereas shrub or woody sites had longer turnover times, ranging from weeks to years. We estimated an overall flux of ∼18 mg m−2 d−1 for the landscape around Fort Simpson. This CH4 flux may increase with the onset of global warming, owing to the fragility of permafrost, resulting in the formation of collapse scars with high CH4 emission rates
Measurement of the branching fractions for B--> D(*)+pi(-)l(-)(nu)over-bar(l) and (B)over-bar(0)-> D-(*)0 pi(+)l(-)(nu)over-bar(l)
No full textWe report on a measurement of the branching fractions for B- --> D(*)+ pi(-)l(-)(nu) over bar (l) and (B) over bar (0) --> D-(*)0 pi(+)l(-)(nu) over bar (l) with 275 x 10(6) B (B) over bar events collected at the Y(4S) resonance with the Belle detector at KEKB. Events are tagged by fully reconstructing one of the B mesons in hadronic modes. We obtain B(B- --> D(+)pi(-)l(-)(nu) over bar (l)) = (0.54 +/- 0.07 (stat) +/- 0.07(syst) +/- 0.06(BR)) x 10(-2), B(B- --> D*+pi(-) l(-) (nu) over bar (l)) (0.67 +/- 0.11 (stat) +/- 0.09(syst) +/- 0.03(BR)) x 10(-2), B((B) over bar (0) --> D(0)pi(+)l(-) (nu) over bar (l)) = (0.33 +/- 0.06(stat) +/- 0.06(syst) +/- 0.03(BR)) x 10(-2), B((B) over bar (0) -->D(*0)pi(+)l(-)(nu) over bar (l)) = (0.65 +/- 0.12(stat) +/- 0.08(syst) +/- 0.05(BR)) x 10(-2), where the third error comes from the error on (B) over bar --> D((*))l(-)(nu) over bar (l) decays. Contributions from B-0 --> D(*+)l(-)(nu) over bar (l) decays are excluded in the measurement of (B) over bar (0) --> D(0)pi(+)l-(nu) over bar (l).Astronomy & AstrophysicsPhysics, Particles & FieldsSCI(E)0ARTICLE5null7
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