6,555 research outputs found
Martin Paper Products, opening
No full textM.J. Foley, President of Powell River Company and Martin Paper Products, Ltd., stands beside Horace Birch Simpson at the opening ceremonies for the Martin Paper Products Kelowna Warehouse
Distinguishing between mechanisms of cell aggregation using pair-correlation functions
No full textMany cell types form clumps or aggregates when cultured in vitro through a variety of mechanisms including rapid cell proliferation, chemotaxis, or direct cell-to-cell contact. In this paper we develop an agent-based model to explore the formation of aggregates in cultures where cells are initially distributed uniformly, at random, on a two-dimensional substrate. Our model includes unbiased random cell motion, together with two mechanisms which can produce cell aggregates: (i) rapid cell proliferation and (ii) a biased cell motility mechanism where cells can sense other cells within a finite range, and will tend to move towards areas with higher numbers of cells. We then introduce a pair-correlation function which allows us to quantify aspects of the spatial patterns produced by our agent-based model. In particular, these pair-correlation functions are able to detect differences between domains populated uniformly at random (i.e. at the exclusion complete spatial randomness (ECSR) state) and those where the proliferation and biased motion rules have been employed - even when such differences are not obvious to the naked eye. The pair-correlation function can also detect the emergence of a characteristic inter-aggregate distance which occurs when the biased motion mechanism is dominant, and is not observed when cell proliferation is the main mechanism of aggregate formation. This suggests that applying the pair-correlation function to experimental images of cell aggregates may provide information about the mechanism associated with observed aggregates. As a proof of concept, we perform such analysis for images of cancer cell aggregates, which are known to be associated with rapid proliferation. The results of our analysis are consistent with the predictions of the proliferation-based simulations, which supports the potential usefulness of pair correlation functions for providing insight into the mechanisms of aggregate formation.D.J.G. Agnew, J.E.F. Green, T.M. Brown, M.J. Simpson, B.J. Binde
Dataset for Simpson et al., 2021
No full textDataset for the observations analysed by Simpson, J.H., Woolway, R.I., Scannell, B., Austin, M.J., Powell, B., & Maberly, S.C. (2021). The annual cycle of energy input, modal excitation and physical plus biogenic turbulent dissipation in a temperate lake. Water Resources Research, 57, e2020WR02944
Vacuum Insulation Panels Applied in Building Constructions
No full textDue to sustainability and due to international treaties, it is desired and required to reduce greenhouse gas emissions drastically. One contributor to these emissions is the burning of fossil fuels for generating power and electricity to be used in and for buildings. Buildings and building-related processes are responsible for about 40% of the primary energy consumption in the European Union. More than half of this energy is applied for heating systems in dwellings and commercial buildings. The European Union therefore has laid down new energy performance requirements for buildings in the European Directive on the Energy Performance of Buildings. Moreover, a reduction of energy losses of buildings during their occupational phase is important for facilitating the implementation of sustainable energy sources in the built environment. Increasing the insulation value of the envelope of buildings may contribute to this reduction of primary energy use. Two strategies can be followed. The first strategy is to increase the thickness of the thermal insulation layer. Until recently, this strategy has primarily been adopted. If, however, German or Swiss Passivhaus standard is applied, the thickness of this insulation layer would increase to beyond 30 cm, resulting in very thick building enclosures. The second, more innovative, strategy for reducing energy losses through the building skin would be the application of more effective thermal insulators. One such more effective thermal insulator is a vacuum insulation panel, abbreviated as VIP. A VIP consists of an open-celled core material which is evacuated and then tightly sealed into a barrier envelope to maintain this vacuum. The vacuum inside the pores of the core material reduces the thermal conductivity of the product significantly, as a result of which the thickness of the insulation layer can be reduced to obtain a certain performance. This reduction of thickness is among the most promising features for large-scale application of VIPs in the building industry. However, integration of VIPs into buildings must be performed very meticulously for several reasons; first, due to its nature a VIP cannot be processed on site and needs careful planning in advance; second, it is very sensitive to mechanical damage thus requiring careful handling; third, thermal bridges along the panel’s edges reduce its performance; fourth, the composite system is highly subjected to aging. This dissertation therefore looks into many of these aspects, presents several calculation tools and shows how VIPs can be applied in façade panels, EPS insulation boards and as under-floor insulation. With the wide-spread proliferation of VIPs in buildings a more sustainable and healthy environment can then be achieved.Building TechnologyArchitectur
Integración aproximada. Resolución de integrales utilizando el método de Simpson
No full textPrimero se justifica brevemente como obtener la fórmula de Simpson. Posteriormente se propone un ejercicio y se resuelve utilizando dicha fórmula.https://media.upv.es/player/?id=2908c100-d4ea-f949-bce7-8779ee61d57eRodríguez Álvarez, MJ. (2015). Integración aproximada. Resolución de integrales utilizando el método de Simpson. https://riunet.upv.es/handle/10251/4941
Social controls of migration and proliferation of neural crest-derived cells in the gut
No full text© 2009 Blackwell Publishing Ltd.D.F. Newgreen, D.C. Zhang, B. Binder, M.J. Simpson, K.A. Landman, H. Enomoto & H.M. Youn
Book Review: Reginald M.J. Oduor’s Introduction to Ethics
No full textTITLE OF BOOK: Introduction to Ethics
AUTHOR: Reginald M.J. Oduor
Nairobi: Sophia Publications Ltd., 2009, 116 pages
COVER: Paperback
ISBN: 9966-7457-0-X
This book is a product of more than a decade of Oduor’s experience in teaching ethics (moral philosophy) at the University of Nairobi. In the course of this introduction, the reader gets to see the techniques of philosophic reflection in action, as they are employed to scrutinise various pertinent moral questions
Setting confidence limits to automatically-generated cursor positions: a simple statistical approach
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