1,900 research outputs found
S.M. Simpson Ltd. -- first chip car, H.B. Simpson
No full textH.B. Simpson climbing up a windscreen beside Canadian National rail cars. Looking east, with Dilworth Mountain in the background. H.B. Simpson was the general manager of the mill at the time. Verso of image reads: "May 1st 1963 1st Chip Car - SMS HB Simpson on Wind Screen.
A rejoinder to Midwinter and Simpson : and how their notes raise further concerns about the financing of the water industry in Scotland
No full textIn separate notes in the last issue of this Commentary, Midwinter and Simpson attempted to allay concerns we had raised about, respectively, the strategic review of water charges for 2002-06 and 2006-10: (Midwinter, 2006 and Simpson, 2006). Here, we show how their notes do nothing to allay the concerns we have raised, and indeed, in certain respects, give rise to further causes for concern
The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha
No full textHeparin-binding epidermal growth factor (HB-EGF), a member of the epidermal growth factor (EGF) family, is implicated in a variety of biological processes, including reproduction. Previous studies describe increased levels of HB-EGF in the human endometrium during the midsecretory stage of the menstrual cycle, suggesting a function for HB-EGF in implantation of the human blastocyst. Here we have investigated the expression and function of the soluble and transmembrane forms of HB-EGF in the human endometrium. We show that the expression of the transmembrane form of HB-EGF in the human endometrium is modulated according to the stage of the menstrual cycle. We present data demonstrating that both the soluble and transmembrane forms of HB-EGF induce DNA synthesis in human endometrial stromal cells. Furthermore, TNFalpha has a cooperative effect on HB-EGF, EGF, TGFalpha, and betacellulin-induced DNA synthesis in stromal cells, suggesting roles for the EGF family and TNFalpha in regeneration and maturation of human endometrium. Induction of DNA synthesis by HB-EGF and its modulation by TNFalpha in endometrial stromal cells are mediated by the EGF receptor and not the HB-EGF receptor ErbB4. Our data suggest key functions for HB-EGF, TNFalpha, and the EGF receptor in endometrial maturation, via autocrine/paracrine and juxtacrine pathways, in preparation for embryo implantation
Memorandum to the Monopolies and Mergers Commission
No full textThe principal authors of this memorandum are Professor J W McGilvray and Professor D R F Simpson. In preparing this paper, we have had the benefit of discussions not only with representatives of the principal parties, but also with a wide range of individuals and organisations whose experience of banking and finance in Scotland, London and overseas we gratefully acknowledge
On the Security of Non-Linear HB (NLHB) Protocol Against Passive Attack
No full textAs a variant of the HB authentication protocol for RFID systems, which relies on the complexity of decoding linear codes against passive attacks, Madhavan et al. presented Non-Linear HB(NLHB) protocol. In contrast to HB, NLHB relies on the complexity of decoding a class of non-linear codes to render the passive attacks proposed against HB ineffective. Based on the fact that there has been no passive solution for the problem of decoding a random non-linear code, the authors have claimed that NLHB’s security margin is very close to its key size. In this paper, we show that passive attacks against HB protocol can still be applicable to NLHB and this protocol does not provide the desired security margin. In our attack, we first linearize the non-linear part of NLHB to obtain a HB equivalent for NLHB, and then exploit the passive attack techniques proposed for the HB to evaluate the security margin of NLHB. The results show that although NLHB’s security margin is relatively higher than HB against similar passive attack techniques, it has been overestimated and, in contrary to what is claimed, NLHB is vulnerable to passive attacks against HB, especially when the noise vector in the protocol has a low weight
The Scottish economy [November 1982]
No full textThe short-term outlook for the Scottish economy remains fairly pessimistic. Though recent falls in interest rates may give a small filip to consumer demand around Christmas, there are no immediate prospects for an upsurge in industrial output. Import propensities are now so high as to negate most of the beneficial effects of an increase in demand. The forecasts detailed below reflect this increasingly pessimistic view of short-term developments in the Scottish economy. Unemployment, which averaged 352,000 in the third quarter of 1982 could rise to 369,000 thousand by the end of 1983 if present trends continue. With no significant stimulus to demand in the offing, any substantive improvement in labour market conditions is likely to be postponed, at least until 1984
Review of the quarter's economic trends [November 1982]
No full textAlthough circumstances are propitious for a modest expansion in output, business confidence is low and there is as yet no indication of the increase in investment necessary for a sustained longer-term recovery. Given the traumatic shocks of the past three years, industry may be slow to respond to relatively modest changes in the exchange rate and in the level of domestic demand, and more substantial pump-priming may be needed to make any impact on current unemployment levels. However, the high level of import propensity means that even a moderately-large growth in demand may not encourage significant growth in output and employment, and may instead lead to the familiar cycle of balance of payments problems, sterling depreciation and higher import prices, and renewed inflation. World economic trends are also considered in this brief paper
Review of the quarter's economic trends [February 1983]
No full textMost forecasters, including the Treasury itself, predict a modest recovery in the economy this year. The emphasis is however on "modest", with predictions for GDP growth in the range of 1.5$-2.5%, and a further rise in unemployment. In the past month however there have been more favourable indications of renewed growth in the international economy, particularly in the United States, and this, combined with the recent depreciation of sterling, will improve the prospects for UK exports. Actual growth in GDP may be therefore nearer the upper end of the recent range of forecasts. Further analysis of the UK's economic prospects, as well as the world economy, are provided in this trend paper
The Scottish economy [February 1983]
No full textIn three weeks' time the Chancellor of the Exchequer will introduce what is politically the most important budget of the last four years. This is so because it is the last budget before the next general election. It is therefore likely to be framed primarily with a view to realising political rather than economic objectives. Whatever the details of the budget, its impact on the economy may be limited. So far as a stimulus to aggregate demand is concerned, the Chancellor's options are extremely limited if he sticks to his previous plans. The difference between planned revenue and planned expenditure for 1983/84 is some £7 billion while the Chancellor's previously announced target for the PSBR in 1983/84 is that it should amount to £8 billion (2.75% of GDP). Thus the Chancellor has only about £1 billion to hand out if he is to keep to his original borrowing targets. However this is distributed, its effect as a boost to spending is almost inconsequential. It would cost £1.2 billion simply to index income tax allowances and thresholds. Yet to deviate further from his pre-set targets will be interpreted as a departure from the path of monetary orthodoxy, a course from which the government has firmly established its determination not to deviate. A modest improvement in output levels in Scottish manufacturing should be possible in the next few months. Following the very depressed levels of output in the final quarter of 1982, increased consumer demand and the increasing competitiveness of Scottish exports should engender a small improvement in business confidence. Prospects in the labour market will not improve. Further analysis and forecasting of Scottish economic conditions over the next quarter are provided
Legal regulation of prices in Tanzania : an examination of the Regulation of Prices Act 1973 as a tool of social change and development
No full textDrawing mainly from the Tazanian experience this study
attempts to review the principal issues in the legal regulation of
prices, by identifying both the general and specific importance
of law in this respect. The position I shall present is that
legal control is both necessary and desirable for the welfare
and social development of the people. The key issue is whether
the market-place will perform its function satisfactory: Will
it produce socially desirable results? If it will not, why will
it not? And will legal regulation help to do the job a little
better?
In an attempt to answer some of these questions,
first of all, outline the basic issues raised by the study in
the first Chapter. Then I examine the general case for price
controls - the theory about the controls, the motives and reasons
for their imposition and the manner in which they are effected
in different economic systems. This is done in Chapter Two. Relying
most on the available literature on the regulatory process, this
Chapter also looks at the relationship between law and economic
regulation and concludes that the effectiveness of law depends
on the existence of a conducive socio-economic environment. In
Chapter Three I describe the past record of price control laws
in Tanzania. I conclude that despite the failure in the past,
the controls still constitute an important policy instrument
in the transition to socialism. In Chapters Four and Five I describe
the manner in which the current regulations are implemented and
the problems encountered. I conclude that the operational performance
of the controls is constrained by internal and external influences on the economic and political life of the country. In the concluding
Chapter I assess the impact of the controls: Do the controls
work? Do people buy goods at the controlled prices? Why today
the controls are almost popularly accepted as worthwhile? I conclude
that while there may be no measurable economic gains derived
by consumers, the controls have a stabilising effect on the social
and political front. In the final section I argue that the
future success of the legislation depends on creating a correspondence
between the economic structures and the control system. What
makes the controls ineffective is not so much defects in the
law but the contradictions between the orientation of and functioning
of the economic system and the ideological commitment
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