74,087 research outputs found
Simpson house
No full textHarry Simpson residence, southwest corner of Howard and D streets. By Clifford M. Ott, January 28, 1976
Simpson house, circa 1930
No full textHarry Simpson residence built in the early 1900s. Located at the southwest corner of Howard and D streets. Picture by Hodgins in the 1930s. Simpson was a grain dealer and farmer of the area
1ST MEASUREMENT OF GAMMA(D(S)(+)-]MU+NU)/GAMMA(D(S)(+)-]PHI-PI+)
No full textComplete Author List:
ACOSTA D, ATHANAS M, MASEK G, PAAR H, BEAN A, GRONBERG J, KUTSCHKE R, MENARY S, MORRISON RJ, NAKANISHI S, NELSON HN, NELSON TK, RICHMAN JD, RYD A, TAJIMA H, SCHMIDT D, SPERKA D, WITHERELL MS, PROCARIO M, YANG S, BALEST R, CHO K, DAOUDI M, FORD WT, JOHNSON DR, LINGEL K, LOHNER M, RANKIN P, SMITH JG, ALEXANDER JP, BEBEK C, BERKELMAN K, BESSON D, BROWDER TE, CASSEL DG, CHO HA, COFFMAN DM, DRELL PS, EHRLICH R, GALIK RS, GARCIASCIVERES M, GEISER B, GITTELMAN B, GRAY SW, HARTILL DL, HELTSLEY BK, JONES CD, JONES SL, KANDASWAMY J, KATAYAMA N, KIM PC, KREINICK DL, LUDWIG GS, MASUI J, MEVISSEN J, MISTRY NB, NG CR, NORDBERG E, OGG M, PATTERSON JR, PETERSON D, RILEY D, SALMAN S, SAPPER M, WORDEN H, WURTHWEIN F, AVERY P, FREYBERGER A, RODRIGUEZ J, STEPHENS R, YELTON J, CINABRO D, HENDERSON S, KINOSHITA K, LIU T, SAULNIER M, SHEN F, WILSON R, YAMAMOTO H, ONG B, SELEN M, SADOFF AJ, AMMAR R, BALL S, BARINGER P, COPPAGE D, COPTY N, DAVIS R, HANCOCK N, KELLY M, KWAK N, LAM H, KUBOTA Y, LATTERY M, NELSON JK, PATTON S, PERTICONE D, POLING R, SAVINOV V, SCHRENK S, WANG R, ALAM MS, KIM IJ, NEMATI B, ONEILL JJ, SEVERINI H, SUN CR, ZOELLER MM, CRAWFORD G, DAUBENMIER CM, FULTON R, FUJINO D, GAN KK, HONSCHEID K, KAGAN H, KASS R, LEE J, MALCHOW R, MORROW F, SKOVPEN Y, SUNG M, WHITE C, WHITMORE J, WILSON P, BUTLER F, FU X, KALBFLEISCH G, LAMBRECHT M, ROSS WR, SKUBIC P, SNOW J, WANG PL, WOOD M, BORTOLETTO D, BROWN DN, FAST J, MCILWAIN RL, MIAO T, MILLER DH, MODESITT M, SCHAFFNER SF, SHIBATA EI, SHIPSEY IPJ, WANG PN, BATTLE M, ERNST J, KROHA H, ROBERTS S, SPARKS K, THORNDIKE EH, WANG CH, DOMINICK J, SANGHERA S, SHELKOV V, SKWARNICKI T, STROYNOWSKI R, VOLOBOUEV I, ZADOROZHNY P, ARTUSO M, HE D, GOLDBERG M, HORWITZ N, KENNETT R, MONETI GC, MUHEIM F, MUKHIN Y, PLAYFER S, ROZEN Y, STONE S, THULASIDAS M, VASSEUR G, ZHU G, BARTELT J, CSORNA SE, EGYED Z, JAIN V, SHELDON P, AKERIB DS, BARISH B, CHADHA M, CHAN S, COWEN DF, EIGEN G, MILLER JS, OGRADY C, URHEIM J, WEINSTEIN A
Data for Envelope Frequency Following Responses to Filtered Word Stimuli
No full textRaw EEG data in .bdf format, collected using a 32-channel ActiveTwo EEG system (BioSemi, the Netherlands). EEG data were measured during presentation of words at an intensity of 70 dB SPL LA eq using ER-2 insert earphones. Words are filtered in different band (0-500 Hz, 0-1000 Hz, 1000-end Hz and 2000-end Hz), with end being 8000 Hz as words were recorded at a sampling rate of 16000 Hz. Stimuli were 3 words presented randomly with an inter-stimulus interval of 1s. Data are published in according with the EPSRC guidelines for data sharing.
Data Supports the paper Vanheusden, F. J., Chesnaye, M. A., Simpson, D. M., & Bell, S. L. (2019). Envelope frequency following responses are stronger for high-pass than low-pass filtered vowels. International Journal of Audiology, 1-9. DOI: 10.1080/14992027.2018.1562243
This dataset, approx 28GB, is available on request via the webform at https://library.soton.ac.uk/datarequest</span
Imaging deep skeletal muscle structure using a high-sensitivity ultrathin side-viewing optical coherence tomography needle probe
No full textPublished 10 Dec 2013Abstract not availableXiaojie Yang, Dirk Lorenser, Robert A. McLaughlin, Rodney W. Kirk, Matthew Edmond, M. Cather Simpson, Miranda D. Grounds, and David D. Sampso
Mineralogical and Micro-structural Investigation into the Mechanical Behaviour of a Soft Calcareous Mudstone
No full textThe construction industry in Abu Dhabi is thriving and its coastline has some of the most ambitious structures in the world. Whilst the subsurface evaporitic and calcareous soft rocks of this region are of great geological interest, they are relatively poorly understood from a geotechnical engineering perspective, forcing foundation designs to be overly conservative. Understanding the stiffness of the underlying geology at small strains is of great importance for the accurate estimation of ground movements around excavations and foundations, and yet routine post-SI laboratory testing programmes tend to focus on basic rock mechanics tests such as UCS tests. These procedures are generally unsuitable for use with calcareous rocks due to their friable and moisture sensitive nature, and rarely obtain parameters representative of actual in situ behaviour. The calcareous mudstone investigated in this paper has mechanical and structural characteristics falling between those of a soil and those typical of a rock and, as such, requires a geotechnical testing approach that combines methods from both soil and rock mechanics disciplines. The mineralogical, micro-structural and mechanical characteristics of this lithology have been examined via a suite of testing techniques, including XRPD, SEM, advanced triaxial with bender elements, along with industry standard procedures. Shearing, tensile and consolidation behaviours have been explored. Examination of the micro- and macro-scale features of this material shows it to be highly structured, with strength and stiffness being controlled by inter-granular bonding of Dolomite grains, as well as by mean effective stress state and rate of strain. The presence of fibrous Palygorskite acts to reduce the degree of bonding, causing specimens rich in this clay mineral to have a more ductile mechanical behaviour
Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes
No full textData source: Supplementary information, http://www.rsc.org/suppdata/c6/mb/c6mb00242k/c6mb00242k1.pdfFourier transform infrared (FTIR) microspectroscopy and confocal imaging have been used to demonstrate that the neutral rhenium(i) tricarbonyl 1,10-phenanthroline complex bound to 4-cyanophenyltetrazolate as the ancillary ligand is able to localise in regions with high concentrations of polar lipids such as phosphatidylethanolamine (PE), sphingomyelin, sphingosphine and lysophosphatidic acid (LPA) in mammalian adipocytes.C. A. Bader, E. A. Carter, A. Safitri, P. V. Simpson, P. Wright, S. Stagni, M. Massi, P. A. Lay, D. A. Brooksa and S. E. Plus
Local factor production by MG63 osteoblast-like cells in response to surface roughness and 1,25-(OH)(2)D-3 is mediated via protein kinase C- and protein kinase A-dependent pathways
No full textTitanium (Ti) surface roughness affects bone formation in vivo and osteoblast attachment, proliferation and differentiation in vitro. MG63 cells exhibit decreased proliferation and increased differentiation when cultured on rough Ti surfaces (R-a > 2 mum) and response to 1,25-(OH)(2)D-3 is enhanced, resulting in synergistic increases in TGF-beta1 and PGE(2). To examine the hypothesis that surface roughness and 1,25-(OH)(2)D-3 exert their effects on local factor production through independent, but convergent, signaling pathways, MG63 cells were cultured on tissue culture plastic or on smooth (PT, R-a = 0.60 mum) and rough (SLA, R-a = 3.97 mum; TPS, R-a = 5.21 mum) Ti disks. At confluence (5 days), cultures were treated for 24h with 10(-8)M 1 alpha ,25-(OH)(2)D-3 and active and latent TGF-beta1 in the conditioned media measured by ELISA. Cell layers were digested with plasmin and released TGF-beta1 was also measured. 1,25-(OH)(2)D-3 regulated the distribution of TGF-beta1 between the media and the matrix in a surface-dependent manner; the effect was greatest in the matrix of cells cultured on SLA and TPS. Inhibition of PKA with H8 for the last 24h of culture increased PGE(2) on SLA and TPS, but when present throughout the entire culture period H8 caused an increase in PGE(2) on all surfaces. 1,25-(OH)(2)D-3 reduced the effect of H8 on PGE(2) production in cultures treated for 24 h. H8 had no effect on TGF-beta1 in the media by itself but caused a complete inhibition of the 1,25-(OH)(2)D-3 dependent increase. Inhibition of PKC with chelerythrine increased PGE(2) in a surface-dependent manner and 1,25-(OH)(2)D-3 reduced the effect of the PKC inhibitor. Chelerythrine also increased TGF-beta1 but the effect was not surface dependent; however, 1,25-(OH)(2)D-3 reduced the effects of chelerythrine with the greatest effects on the smooth surface. Thus, the distribution of TGF-beta1 between the media and the matrix is regulated by 1,25-(OH)(2)D-3 in a surface-dependent manner. Surface roughness exerts its effects on TGF-beta1 production via PKC but not PKA. The effect of 1,25-(OH)(2)D-3 on TGF-beta1 production is not via PKC. PKA is involved in the surface-dependent regulation of PGE(2) but not in the regulation of PGE(2) by 1,25-(OH)(2)D-3 on rough surfaces. Regulation of PKC affects PGE(2) production but it is not involved in the surface roughness dependent response to 1,25-(OH)(2)D-3. These results suggest two independent but interconnected pathways are involved. (C) 2001 Elsevier Science Ltd. All rights reserved.NIDCR NIH HHS [DE-05937, DE-08603
Apatite laser-ablation Lu-Hf - U-Pb tandem thermochronology: a novel method to constrain high temperature thermal histories
No full textGlorie S., Kharkongor M., Bedoya A., Hand M., Simpson A., Nixon A., Kirkland C., Chew D
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