3,074 research outputs found
Differential spatio-temporal expression of alpha-dystrobrevin-1 during mouse development.
Dystrobrevins are a family of dystrophin-related and dystrophin-associated proteins. alpha-dystrobrevin-1 knockout mice suffer from skeletal and cardiac myopathies. It has been suggested that the pathology is caused by the loss of signalling functions but the exact role of dystrobrevins is largely unknown. We have analysed the spatial and temporal expression of alpha-dystrobrevin-1 during mouse embryogenesis and found striking developmental regulation and distribution patterns. During development this protein was expressed not only in muscle but also in the CNS, sensory organs, epithelia and skeleton. Particularly interesting was the correlation of alpha-dystrobrevin-1 expression with the induction of various differentiation processes in the developing eye, inner ear, pituitary, blood-brain barrier, stomach epithelium and areas of the brain, dorsal root ganglia and spinal cord. In contrast, this specific expression at the induction phase decreased/disappeared at later stages of development
Identifying skill sets for repository staff [Dataset]
Data from an online survey designed to identify the skill and knowledge sets required to work on a digital repository in Australia and New Zealand. The survey was conducted by Dr. Joanna Richardson and Ms. Natasha Simons from Griffith University, Australia. The response rate for the survey was 37.3%Full Tex
Draft toxicological profile for JP-5, JP-8, and jet A fuels
A Toxicological Profile for JP-5 and JP-8 was released in 1998. This present edition supersedes any previously released draft or final profile.Chemical manager(s)/author(s): John Risher, Obaid Faroon, ATSDR, Division of Toxicology and Human Health Sciences, Atlanta, GA; Fernando Llados, Lisa Ingerman, Mario Citra, SRC, Inc., North Syracuse, NY
Shock tube study of JP-10 ignition delay time
JP-10 (exo-tetrahydrodicyclopentadiene, C10H16) ignition delay times were measured in a preheated shock tube. The vapor pressures of the JP-10 were measured directly by using a high-precision vacuum gauge, to remedy the difficulty in determining the gaseous concentrations of heavy hydrocarbon fuel arising from the adsorption on the wall in shock tube experiments. The whole variation of pressure and emission of the OH or CH radicals were observed in the ignition process by a pressure transducer and a photomultiplier with a monochromator. The emission of the OH or CH radicals was used to identify the time to ignition. Experiments were performed over the pressure range of 151-556 kPa, temperature range of 1000-2100 K, fuel concentrations of 0.1%-0.55% mole fraction, and stoichiometric ratios of 0.25, 0.5, 1.0 and 2.0. The experimental results show that for the lower and higher temperature ranges, there are different dependency relationships of the ignition time on the temperature and the concentrations of JP-10 and oxygen
Dynamics of Network Formation Processes in the Co-Author Model
This article studies the dynamics in the formation processes of a mutual consent network in game theory setting: the Co-Author Model. In this article, a limited observation is applied and analytical results are derived. Then, 2 parameters are varied: the number of individuals in the network and the initial probability of the links in the network in its initial state. A simulation result shows a finding that is consistent with an analytical result for a state of equilibrium while it also shows different possible equilibria.Dynamics, Network, Game Theory, Model,Simulation, Equilibrium, Complexity
The Simons Array CMB polarization experiment
International audienceThe Simons Array is a next generation cosmic microwave background (CMB) polarization experiment whose science target is a precision measurement of the B-mode polarization pattern produced both by inflation and by gravitational lensing. As a continuation and extension of the successful POLARBEAR experimental program, the Simons Array will consist of three cryogenic receivers each featuring multichroic bolometer arrays mounted onto separate 3.5m telescopes. The first of these, also called POLARBEAR-2A, will be the first to deploy in late 2016 and has a large diameter focal plane consisting of dual-polarization dichroic pixels sensitive at 95 GHz and 150 GHz. The POLARBEAR-2A focal plane will utilize 7,588 antenna-coupled superconducting transition edge sensor (TES) bolometers read out with SQUID amplifiers using frequency domain multiplexing techniques. The next two receivers that will make up the Simons Array will be nearly identical in overall design but will feature extended frequency capability. The combination of high sensitivity, multichroic frequency coverage and large sky area available from our mid-latitude Chilean observatory will allow Simons Array to produce high quality polarization sky maps over a wide range of angular scales and to separate out the CMB B-modes from other astrophysical sources with high fidelity. After accounting for galactic foreground separation, the Simons Array will detect the primordial gravitational wave B-mode signal to r > 0.01 with a significance of > 5σ and will constrain the sum of neutrino masses to 40 meV (1σ) when cross-correlated with galaxy surveys. We present the current status of this funded experiment, its future, and discuss its projected science return.© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only
An equivalent formulation of the Fan-Raspaud Conjecture and related problems
In 1994, it was conjectured by Fan and Raspaud that every simple bridgeless cubic graph has three perfect matchings whose intersection is empty. In this paper we answer a question recently proposed by Mkrtchyan and Vardanyan, by giving an equivalent formulation of the Fan-Raspaud Conjecture. We also study a possibly weaker conjecture originally proposed by the first author, which states that in every simple bridgeless cubic graph there exist two perfect matchings such that the complement of their union is a bipartite graph. Here, we show that this conjecture can be equivalently stated using a variant of Petersen-colourings, we prove it for graphs having oddness at most four and we give a natural extension to bridgeless cubic multigraphs and to certain cubic graphs having bridges
Ephemisms as communication vehicle in the Tiv language and literature
The beauty of Tiv language and literature is achieved when communication or discourse is laced with euphemistic expressions. Euphemisms aid in turning impolite utterances into polite ones. This study, therefore, investigates the communicative potentials of euphemisms in the Tiv language and literature. The study discusses formations of euphemisms, classifies euphemisms and explores the effects of euphemisms. Connotative theory of meaning has been deployed in this study because the interpretation of euphemisms is contextually and connotatively loaded. Methodologically, the author used primary and secondary materials. The author used a participant-observation tool for data collection. Being a native speaker of the Tiv language, the author collected, translated and classified euphemisms. Secondary materials were sourced from textbooks, journal articles, online sources and dictionaries. The following findings were made: euphemisms constitute phrasal or idiomatic synonyms; they beautify or spice our daily communication; they can becloud meanings. This study will benefit preachers, writers, lecturers/teachers, researchers, semanticists, public speakers, politicians and students
Open Access to Peer-Reviewed Research through Author/Institution Self-Archiving: Maximizing Research Impact by Maximizing Online Access
All refereed journals will soon be available online; most of them already are. This means that anyone will be able to access them from any networked desk-top. The literature will all be interconnected by citation, author, and keyword/subject links, allowing for unheard-of power and ease of access and navigability. Successive drafts of pre-refereeing preprints will be linked to the official refereed draft, as well as to any subsequent corrections, revisions, updates, comments, responses, and underlying empirical databases, all enhancing the self-correctiveness, interactivity and productivity of scholarly and scientific research and communication in remarkable new ways. New scientometric indicators of digital impact are also emerging <http://opcit.eprints.org> to chart the online course of knowledge. But there is still one last frontier to cross before science reaches the optimal and the inevitable: Just as there is no longer any need for research or researchers to be constrained by the access-blocking restrictions of paper distribution, there is no longer any need to be constrained by the impact-blocking financial fire-walls of Subscription/Site-License/Pay-Per-View (S/L/P) tolls for this give-away literature. Its author/researchers have always donated their research reports for free (and its referee/researchers have refereed for free), with the sole goal of maximizing their impact on subsequent research (by accessing the eyes and minds of fellow-researchers, present and future) and hence on society. Generic (OAi-compliant) software is now available free so that institutions can immediately create Eprint Archives in which their authors can self-archive all their refereed papers for free for all forever <http://www.eprints.org/>. These interoperable Open Archives <http://www.openarchives.org> will then be harvested into global, jointly searchable "virtual archives" (e.g., <http://arc.cs.odu.edu/>). "Scholarly Skywriting" in this PostGutenberg Galaxy will be dramatically (and measurably) more interactive and productive, spawning its own new digital metrics of productivity and impact, allowing for an online "embryology of knowledge.
Why hasn't electronic bill presentment and payment taken off?
The delivery and payment of bills over the Internet could offer many advantages—low processing costs and enhanced marketing opportunities for billers, savings in time and postage for customers. Nevertheless, electronic billing has not found favor with potential users. A lack of coordination among billers and customers, combined with the high fixed costs of the new technology, may help account for the cool reception.Electronic funds transfers ; Electronic commerce ; Technology ; Payment systems
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