1,721,292 research outputs found
Which REE prediction equation should we use in normal-weight,overweight and obese women?
No full textWhich REE prediction equation should we use in normal-weight,overweight and obese women?
No full textValidity of some prediction equations to assess resting energy expenditure (REE) in 29 elderly obese subjects (>60 years)
No full textBACKGROUND AND AIMS: Recent estimates in US have shown that more than a third of 65 years old subjects are obese. The objective of this study was to test the accuracy of six prediction equations to estimate resting energy expenditure (REE) in elderly obese subjects (age >60 years). METHODS: Twenty-nine obese Caucasian male (n=8) and female (n=21) subjects (age range: 60-77 years) attended the Outpatient Clinic of the Neuroscience Department of Naples "Federico II" University Medical School (Italy), Section of Aging and Nutrition from January 2005 to January 2006. Weight, height, BMI and body composition (bioimpedance) were measured. REE was measured using a ventilated-hood indirect calorimetry and compared to six prediction equations (Harris-Benedict, Fredrix, Mifflin, Owen, WHO, Livingston). RESULTS: Mean age and body mass index (BMI) were 65.9+/-4.8 years and 36.8+/-5.3 kg/m2, respectively. The measured REE was 1658+/-289 kcal/day. The Harris-Benedict', Owen' and Livingston's equations performed less well than the other equations and they showed a tendency towards underestimation. The equation with the best REE prediction was the Fredrix's one (DeltaREE=-19.4kcal/day) with 66% of REE predictions lying within 10% of measured REE. CONCLUSIONS: These data support the utilization of the Fredrix's equation to calculate REE in obese elderly subjects
Fisiologia e metodi di misura della produzione di ossido nitrico nell’uomo
No full textNitric oxide (NO) is a simple molecule, highly conserved across species with important effects on several physiological mechanisms. In the cardiovascular system, NO is tonically released by the endothelial cells in response to shear stress to maintain vascular tone. This effect is due to the relaxation of the vascular smooth muscle cells in the medium layer (tunica media) of the arterial wall. However, NO is also involved in the regulation of synaptic neurotransmission, platelet aggregation, inflammation, appetite, peristalsis, renal metabolism, respiratory function, lipid metabolism and glucose metabolism. Therefore, an abnormal production of NO (over- or under-production) has multi-systemic effects. Metabolic disorders like hypertension, obesity or dyslipidaemia are associated with a reduction of NO production. The mechanisms responsible for a decreased NO synthesis are partially known but oxidative stress, overproduction of endogenous inhibitors of the Nitric Oxide Synthase (NOS) such as asymmetric dimethylarginine (ADMA) and genetic factors may be implicated. The half-life of NO is extremely short in biological samples (t1/2 < or = 0.2 sec) and its in vivo measurement is very difficult. Therefore, indirect methods have been developed to measure the end products of NO metabolism in biological samples. Some of these methods have used stable isotopes to trace the metabolic fate of the precursor of NO (Arginine) and measure the appearance of stable isotopes in the end products [nitrate (NO3), nitrite (NO2), citrulline]. However, the existing methods are expensive, invasive and require complex analytical laboratory techniques
Which REE prediction equation should we use in normal-weight,overweight and obese women?
No full textAgeing, adiposity indexes and low muscle mass in a clinical sample of overweight and obese women
No full textAccuracy of predictive equations for the measurement of resting energy expenditure in older subjects
No full textFirst-borns have a higher metabolic rate and carry a higher metabolic risk in young women attending a weight loss clinic.
No full textBACKGROUND: Birth order has been associated with variability in early life growth and subsequent obesity risk, but the consequent metabolic risks have not been assessed. OBJECTIVE: To quantify the metabolic risk in young adulthood of being first-born relative to those born second or subsequently. METHODS: Body composition, resting metabolic rate and metabolic risk were assessed in 383 women, aged 18-35 years, from a clinical setting in southern Italy. RESULTS: First-borns had increased body mass index, adiposity and metabolic risk (p<0.05) and increased resting metabolic rate adjusted for fat-free mass (p<0.05) in the Italian women. CONCLUSION: First-born status is associated with significantly elevated metabolic risk in a clinical population of overweight and obese young women attending a weight loss clinic. If these findings are confirmed in other studies, they may suggest that the prevalence of the metabolic syndrome worldwide may increase as a function of the trend to smaller family size
Post-challenge hyperglycemia, nitric oxide production and endothelial dysfunction: the causal role of asymmetric dimethylarginine (ADMA)
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