530 research outputs found
Tettagalma Menon, new genus
No full text<i>Tettagalma</i> Menon, new genus <p> <b>Diagnosis.</b> Medium­sized (25 mm forewing length) tettigarctid; prominent costal margin; Rs with three branches; origin of MA branches proximal to nodal line; CuA strongly deflected anteriorly at nodal line; wide marginal membrane; marginal membrane bearing numerous, equidistant striae.</p> <p> <b>Etymology.</b> Genus­group name formed from a combination of <i>tetti</i> in reference to the family and <i>agalma</i> from the Greek present, gift, as the specimen was donated to the author.</p> <p> <b>Type locality and horizon.</b> Vicinity of Nova Olinda, Nova Olinda Member, Crato Formation.</p> <p> <b>Type species.</b> <i>Tettagalma striata</i> Menon new genus and species, by monotypy.</p>Published as part of <i>Menon, Federica, 2005, New record of Tettigarctidae (Insecta, Hemiptera, Cicadoidea) from the Lower Cretaceous of Brazil, pp. 53-58 in Zootaxa 1087</i> on page 54, DOI: <a href="http://zenodo.org/record/170508">10.5281/zenodo.170508</a>
An overview of direct somatic reprogramming: The ins and outs of iPSCs
No full textStem cells are classified into embryonic stem cells and adult stem cells. An evolving alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs), which have a multi-lineage potential comparable to conventionally acquired embryonic stem cells with the additional benefits of being less immunoreactive and avoiding many of the ethical concerns raised with the use of embryonic material. The ability to generate iPSCs from somatic cells provides tremendous promise for regenerative medicine. The breakthrough of iPSCs has raised the possibility that patient-specific iPSCs can provide autologous cells for cell therapy without the concern for immune rejection. iPSCs are also relevant tools for modeling human diseases and drugs screening. However, there are still several hurdles to overcome before iPSCs can be used for translational purposes. Here, we review the recent advances in somatic reprogramming and the challenges that must be overcome to move this strategy closer to clinical application
What Does It Mean for Qualia to be Intrinsic?
No full textAn intrinsic property of an object is intuitively understood as the property which the object can have independent of all other objects. The notion of an intrinsic property figures prominently in the debates over consciousness. One of the arguments for the rejection of traditional physicalism—the thesis that all reality, including qualia, are physical—has been the claim that physical properties are merely extrinsic or relational, while qualia are intrinsic. What does it mean for a property to be intrinsic, and why do not physical properties qualify as intrinsic? This chapter is an attempt to make sense of the intrinsic/extrinsic distinction. It looks at two attempts at precisely defining an intrinsic property, and at an argument for epistemic humility—the thesis that we have no knowledge of intrinsic properties at all. It shall be argued that one exception can be made to the humility thesis—qualia. The qualia-as-intrinsic thesis is likely to have significant implications for various debates in philosophy of mind, and metaphysics, of which two shall be explored here. It shall be argued that given this thesis: (i). Combination of experiences is not possible. If one further assumes ontological monism, this thesis leads us to the conclusion that all entities are simples—such that they cannot be divided (ii). Relational properties are not reducible to intrinsic properties
Novel Dialogue 2.3: Because I Couldn't Be a Dancer: Sigrid Nunez and Tara Menon (JP)
No full textThe brilliant New York writer Sigrid Nunez's most recent novel is What Are You Going Through; her previous one, The Friend, (2018) won the National Book Award. She speaks with Tara Menon, of the Harvard English department, and author of a terrific article about Sigrid Nunez in the Sewanee Review. The conversation ranges widely and then plunges into depths. Because life is defined by grief and mourning, so too are my novels, says Nunez. She thinks her upbringing with immigrant parents who felt adrift from their homeland and her own "failure" as a dancer (recounted in her 1995 debut novel, A Feather on the Breath of God ) are the ferment from which her vocation as a writer arose. The question of genre is tossed around: "fictional memoir" perhaps, which gets confused (insultingly, Tara thinks!) with auto-fiction. But Sigrid is fascinated by establishing a reality that is entirely made-up ("not a single friend angry!"), yet also documentary in nature. Perhaps the best tag for her work is "essay novel": that allows one to do what Javier Marias calls "literary thinking." And there's a wonderfully non-Pavlovian answer to the treat question: sometimes you can just have the whiskey
A priori and a posteriori analysis of the hybrid two-level large-eddy simulation method for high Reynolds number complex flows
No full textWe present a priori and a posteriori analysis of the assumptions and predictions of the hybrid two-level large-eddy simulation (TLS-LES) method for high Reynolds number complex flows. The TLS-LES methodology is a multi-scale framework for simulation of turbulent flows in complex configurations at practically relevant Reynolds number. It additively combines the two-level simulation (TLS) model with a conventional large-eddy simulation (LES) approach by employing a static or dynamic blending function. In the present study, first we analyze the model assumptions employed by the TLS model to obtain the small-scale solution necessary for closure of the large-scale equations. Afterward, we analyze the large-scale and small-scale solutions to assess the predictive ability of the multi-scale framework for specific turbulence physics such as role of forward and backscatter of energy and presence of co- and counter-gradient diffusion. To perform these investigations, we consider cases with increasing degree of geometrical complexity, namely, flow in a periodic channel, flow past a bump placed on the lower surface of the channel and flow past a finite-span NACA0015 airfoil
Il bene del filosofo e il limite della città. Sulla politica filosofica di Leo Strauss
No full textThe intention of this paper is to show how Leo Straussʼ mature writings respond to the twofold necessity of political philosophy: contributing, at the same time, to the good of the city and to the good of the philosophers. In the first place, it will try to prove this point by analyzing in detail the Introduction to On Tyranny (1948), which represents an essential step in order to understand the intention of the author. In the second place, it will tackle the problem of justice, that is, of natural right, by concentrating on the so called " tyrannical teaching ". This teaching is a way to present a truth which the city cannot find acceptable, that is, an unpleasant truth concerning the irresoluble problem of justice and legitimacy. In conclusion, it will point to the tension between philosophy, i.e., search for knowledge, and the city, i.e., the realm of opinion. For the philosopher, as such, has to " corrupt " the young in order to pursue his search for knowledge of the whole, or the nature of all things. Therefore, he weakens the city, since philosophizing implies unbelief in the gods of the city
Equivariant elliptic cohomology and twisted equivariant k-theory
No full textEquivariant elliptic cohomology and twisted equivariant K-theory are both related to the representations of loop groups. After making these relationships precise, we propose a map from twisted equivariant elliptic cohomology to twisted K-theory of the inertia stack using equivariant de Rham models. This proposal agrees with the Freed-Hopkins-Teleman q = 1 map from characters of representations of loop groups to distributions associated to twisted equivariant K-theory classes.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-08-01The student, Dileep Menon, accepted the attached license on 2019-05-24 at 15:54.The student, Dileep Menon, submitted this Dissertation for approval on 2019-05-24 at 16:06.This Dissertation was approved for publication on 2019-05-28 at 10:50.DSpace SAF Submission Ingestion Package generated from Vireo submission #13991 on 2019-11-26 at 13:00:58Made available in DSpace on 2019-11-26T20:49:00Z (GMT). No. of bitstreams: 4
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Previous issue date: 2019-05-28Embargo set by: Seth Robbins for item 112889
Lift date: 2021-11-26T20:49:41Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112889 on 2021-11-27T10:15:09Z
A cross-sectional analysis of barriers to health-care seeking among medical students across training period
No full textBackground and Aims: Very little information is available on how needs and perceptions to service utilization may change with duration of medical training. Our objective was to compare the self-reported barriers to health-care seeking for mental and physical health services separately between 1st year and final year medical students. Methods: In this cross-sectional study, we invited all medical students of the concerned cohorts to complete a prevalidated checklist and 28-item self-reported questionnaire about perceived barriers to health-care seeking. The questionnaire had separate items pertaining to usage of mental and physical health-care services. Results: The response rate of the 1st year and final year cohorts were 83.8% and 86.6%, respectively. Lack of time, unawareness about where to seek help, cost issues, and fear of future academic jeopardy were more common concerns among 1st year students to the usage of mental health services (odds ratio [OR] 0.27, 0.45,0.09, and 0.49, respectively) whereas issues of stigma were more commonly reported by final year students for using mental health services (OR = 2.87). In contrast, the barriers in using physical health services were broadly comparable between the two cohorts. Conclusion: Differences exist between medical students in various years of training particularly with regard to self-reported barriers and perceptions particularly about using mental health-care services. This may have key implications for designing and delivery of service provisions in this group
Risk-reducing early salpingectomy and delayed oophorectomy as a two-staged alternative for primary prevention of ovarian cancer in women at increased risk: a commentary.
No full textThis is the peer reviewed version of the following article: Gaba, F. , Piek, J. , Menon, U. and Manchanda, R. (2019), Risk reducing early salpingectomy and delayed oophorectomy as a two staged alternative for primary prevention of ovarian cancer in increased risk women: a commentary. BJOG: Int J Obstet Gy. Accepted Author Manuscript. doi:10.1111/1471-0528.15651, which has been published in final form at https://doi.org/10.1111/1471-0528.15651. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Version
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