6,456 research outputs found
The Memoirs of a Retooled Geoscientist or How I Came to Know and Love Remote Sensing
Dr. Nicholas M. Short is a former employee at NASA Goddard Space Flight Center and is the author of numerous books touching on the subject of remote sensing. He gained his B.S. from St. Louis University, an M.A. from Washington University, and received his PhD in 1958 from MIT
Heritability and Linkage Analysis of Appendicitis Utilizing Age at Onset
Appendicitis usually afflicts the young, but there is a large tail in the distribution of onset age. The genetics of this disease are still not well understood. A heritability analysis and genome wide linkage analysis of a large twin dataset was undertaken. Treating age of onset of appendicitis as a censored survival trait revealed a heritability of 0.21, and found evidence of linkage to Chromosome 1p37.3. Author(s): Christopher Oldmeadow 1 * | Kerrie Mengersen 2 | Nicholas Martin 3 | David L. Duffy
Behavior of trace elements in rock weathering and soil formation
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Geology and Geophysics, 1958.MIT Institute Archives copy: includes a rev. abstract and two additional graphs. Also includes typed letter signed, Nick Short to Dear Bill [William H. Dennen], 1958 Apr. 11, discussing the finished graphs and the recommended changes in the abstract.Vita. "June 1958."Includes bibliographical references (leaves 212-217).by Nicholas Martin Short.Ph.D
The cult of St Nicholas in medieval Italy
St Nicholas was one of the most popular saints in medieval Italy. His cult attracted the attention
of popes, kings and emperors, and his shrine at Bari became an important international pilgrimage
destination. This thesis asks how the cult of St Nicholas came to be so widespread and popular in
Italy, and why the saint attracted the attention of diverse groups and individuals.
This thesis is structured around four chapters. The first demonstrates that through a
process of Latinisation the cult of St Nicholas became integrated within Italian literary traditions
and within a new spiritual era. Chapter Two reveals that this Latinisation also occurred within the
saint’s iconography. Chapters Three and Four are case studies of the cult in Puglia and Venice,
locations which claimed possession of the saint’s relics. These case studies show that the general
developments that the cult of St Nicholas underwent in Italy, identified in Chapters One and Two,
did not apply universally. Instead, the presence of the saint’s relics resulted in a different profile
of the saint in Bari and Venice. Through the process of Latinisation, the cult of St Nicholas
became updated and remained relevant for its new Italian audience; Chapters Three and Four
show alternative ways that the cult of St Nicholas gained widespread popularity.
This thesis presents for the first time an iconographical study of St Nicholas in Italian art,
which develops existing research of the saint’s Byzantine iconography. Chapter Four presents a
profile of the cult of St Nicholas in Venice in the Middle Ages, which is a significant oversight in
the literature. The thesis uses a variety of visual and textual sources, in particular fresco and
altarpiece representations, archival documents from Venice and Rome (including the Apostolic
Visitations), and under-exploited contemporary and antiquarian Venetian sources
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A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints
In an adaptive seamless phase II/III clinical trial interim
analysis data are used for treatment selection, enabling resources to be focussed on comparison of more effective treatment(s) with a control. In this paper we compare two methods recently proposed to enable use of short-term endpoint data for decision-making at the interim analysis. The comparison focusses on the power and the probability of correctly identifying the most promising treatment. We show that the choice of method depends on how well short-term data predict the best treatment, which may be measured by the correlation between treatment effects on short-term and long-term endpoints
Forbidden Colors in the Regulation of Clerical Dress from the Fourth Lateran Council (1215) to the Time of Nicholas of Cusa (d. 1464)
Medieval canon law attempted to distinguish clergy from the laity by restricting their dress choices. The article focuses on prohibition of wearing red or green on the street. Both colors were identified with the nobility.The published version was published as Chapter 7 in Medieval Clothing and Textiles 1Izbicki, Thomas M. (2005), "Forbidden Colors in the Regulation of Clerical Dress from the Fourth Lateran Council (1215) to the Time of Nicholas of Cusa (d. 1464)" in Netherton, Robin and Owen-Crocker, Gale R., eds., Medieval Clothing and Textiles 1 (Boydell Press),105-114ISBN: 9781843831235 (published book
The maternal immune system during pregnancy and its influence on fetal development
The maternal immune system plays a critical role in the establishment, maintenance, and completion of a healthy pregnancy. However, the specific mechanisms utilized to achieve these goals are not well understood. Various cells and molecules of the immune system are key players in the development and function of the placenta and the fetus. Effector cells of the immune system act to promote and yet limit placental development. The T helper 1 (Th1)/T helper 2 (Th2) immune shift during pregnancy is well established. A fine balance between proinflammatory and anti-inflammatory influences is required. We herein review the evidence regarding maternal tolerance of fetal tissues and the underlying cell-mediated immune and humoral (hormones and cytokines) mechanisms. We also note the many unanswered questions in our understanding of these mechanisms. In addition, we summarize the clinical manifestations of an altered maternal immune system during pregnancy related to susceptibility to common viral, bacterial, and parasitic infections, as well as to autoimmune diseases.Peer reviewe
External interventions and the duration of civil wars
The authors combine an empirical model of external intervention, with a theoretical model of civil war duration. Their empirical model of intervention allows them to analyze civil war duration, using"expected"rather than"actual"external intervention as an explanatory variable in the duration model. Unlike previous studies, they find that external intervention is positively associated with the duration of civil war. They distinguish partial third-party interventions that extend the length of war, from multilateral"peace"operations, which have a mandate to restore peace without taking sides - and which typically take place at war's end, or at least when both sides have agreed to a cease-fire. In a future paper, the authors will examine whether partial third-party interventions - whatever their effect on a war's duration - increase the risk of war's recurrence. If that proves true, then even if interventions reduce the length of civil war, they may do so at the cost of further destabilizing the political system, and sowing the seeds of future rebellion.Children and Youth,Peace&Peacekeeping,Post Conflict Reconstruction,Post Conflict Reconstruction,International Affairs,Post Conflict Reconstruction,Social Conflict and Violence,Peace&Peacekeeping,Post Conflict Reconstruction,International Affairs
Christiformitas in Nicholas of Cusa’s Roman Sermons (1459)
Nicholas of Cusa (1401-1464) served as vicar of Rome in the absence of Pope Pius II at the Congress of Mantua (1459). Cusanus held a synod and did visitations of major churches. His sermons for these events emphasized conformity with Christ as the means of knowing God.This is the Version of Record (VoR) of the article that was originally published in Perspectives in the Arts and Humanities Asia, Volume 1, Number 1 (2011
Reintroducing Bunky at 125: E.M. Jellinek’s life and contributions to Alcohol Studies
Objective:
Elvin Morton Jellinek (1890–1963) was one of the founders of modern addiction science. This overview is a brief survey of his life and achievements, intended to re-introduce alcohol scholars to his contributions (and possible failings) as well as stimulate interest and historical research in the field.
Method:
The article draws largely from the archival collection of the Rutgers Center of Alcohol Studies (CAS) Library and the Jellinek memorial issue of the CAS Information Services Newsletter. Scholarly works and personal and institutional records by or about E. M. Jellinek were assembled and, when necessary, translated into English.
Results:
Born in 1890 in New York and raised in Hungary, Jellinek studied at several European universities and worked for various institutions and organizations in Budapest (1914–1920), Sierra Leone, Honduras, and at the Worcester State Hospital, in Massachusetts. In 1941 he became an associate professor of applied physiology at Yale University, where he directed the Yale Summer School of Alcohol Studies from 1941 to 1950. After more than a decade of work with the World Health Organization and several Canadian institutions, he taught and conducted research at the Institute for the Study of Human Problems at Stanford University until his death in 1963. Jellinek was a pioneer in research on the nature and causes of alcoholism and was an early proponent of the disease theory of alcoholism.
Conclusions:
With the help of E. M. Jellinek, the modern era of addiction science was launched with an international outlook that included critical attention to the physical infrastructure and intellectual capital needed to form an interdisciplinary field of basic research, applied science, and clinical practice.Peer reviewe
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