667 research outputs found
A systematic review of epidemiological studies on the prevalence of complementary and alternative medicine (CAM) use by paediatric cancer patients. Presented at ECIM 2008.
No full textBackground: paediatric cancer patients are likely to use complementary and alternative medicines (CAMs) alongside more conventional interventions. A number of individual studies have been carried out to examine prevalence rates of CAM use amongst paediatric cancer patients. These studies have varied findings and are of mixed quality. This meta-analytic review therefore aimed to assess the quality of this literature and to determine what is known about the prevalence of the CAM use in paediatric cancer. Secondary research questions focused on the types of CAM used, trends in CAM use over time, reasons for CAM use, and demographic characteristics associated with CAM use.Method: electronic and manual searches for relevant studies identified 26 English language journal articles of primary research studies investigating the prevalence of CAM usage among paediatric cancer patients in peer-reviewed journals. A quality assessment checklist was rigorously developed based on the strengthening the reporting of observational studies in epidemiology (STROBE) statement in collaboration with Dr. Erik von Elm (lead author of the STROBE statement). Data were extracted and validated by more than one author and analysed using meta-analytic techniques.Results: the prevalence of CAM use by paediatric cancer patients ranged from 40% to 53%. The quality of the studies was mixed and did not correlate with the estimated prevalence of CAM use. ‘Herbals’ was the most popular CAM modality. Paediatric cancer patients use CAM for various reasons. Higher level of education and income were associated with CAM use in North America; the opposite was true for CAM use in Mexico and Turkey.Conclusion: a substantial proportion of paediatric cancer patients use CAM. There is a need to use standardised definitions of the CAM in future studies to generate comparable data. The quality assessment checklist has potential to be a useful quality assessment instrument for other reviews of similar epidemiological studie
Microchip electrophoresis for UVC-induced DNA damage assessment
No full textIn this thesis a design is presented which main objectives are to improve the speed, sensitivity and resolution of the commonly used gel electrophoresis method. To this end a background study is performed to look at the differences and similarities between both gel and micro-chip electrophoresis. Based on these findings some calculations are done to see if the expected design can theoretically improve in the above mentioned fields. A design is created and later fabricated in order to obtain these objectives. For the design a glass substrate is used with integrated electrodes, combined with a PMT sensor system to process the signals from the chip via a computer program. The main techniques used for the fabrication are wet etching and wafer bonding. The testing results produce a clear signal, which shows improvements in sensitivity and resolution, as well as producing results in less than three minutes.Microelectronics & Computer EngineeringElectrical Engineering, Mathematics and Computer Scienc
The study on polymer melt front, gas front and solid layer in filling stage of gas-assisted injection molding
No full textVARIATIONAL APPROACH FOR THE ANALYSIS OF VERTICALLY LOADED PILE GROUPS AND PILED RAFT FOUNDATIONS
No full textPh.DDOCTOR OF PHILOSOPH
Impact of Static Sea Surface Topography Variations on Ocean Surface Waves
No full textElectrical Engineering, Mathematics and Computer ScienceDelft Institute of Applied Mathematic
ShopHouse Transformation: Appraisal of the pre-war shophouse and its contemporary application
No full textWe are now faced with new social problems of deteriorating sense of community and a disjointed society that is generated by the Modern city paradigms. To tackle these new problems does not mean the complete restoration of the old system. It should mean a new typology that reflects the traditional system in an innovative way. By mixing the old buildings with the new ones through the injection of new communication platforms that encourage communication among people from different cultures and backgrounds, a more well-balanced society will be the new model for the future.Housing NeighborhoodsRMITArchitectur
Modeling of nonstationary earthquake ground motion and biaxial and torsional response of inelastic structures
No full textA systematic way to analyze the response of inelastic structures under bi-directional random excitations is developed. Most of the system and excitation characters have been considered, e.g., hysteretic behavior of restoring force, biaxial interaction, torsional response and degradation of the structure, and nonstationary behavior of ground excitation. A new stochastic ground motion model is proposed in which both intensity and frequency content are functions of time. Corresponding methods for estimating the model parameters based on actual earthquake records are also given. The proposed ground motion model can be efficiently applied to simulations as well as analytical solutions of random vibration and reliability studies for inelastic structures. Responses of single-mass inelastic systems and three-story space frames, with or without deterioration, under bi-directional non-stationary ground excitations are investigated via an equivalent linearization method and Monte Carlo simulations. The results show that (1) the equivalent linearization method predicts the response statistics quite well except for r.m.s. displacement, which can be improved by the proposed semi-empirical equation; (2) the time-varying frequency content of ground excitation has significant effects on the response of inelastic structures, especially when the excitation dominant frequencies are close to the structural pre-yielding natural frequency; (3) biaxial and torsional response may become significant in an asymmetric structure.Made available in DSpace on 2011-05-07T13:19:38Z (GMT). No. of bitstreams: 2
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High-speed imaging of giant unilamellar vesicle production in cDICE
No full textGreen Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.BN/Marileen Dogterom LabFluid MechanicsBN/Gijsje Koenderink La
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