1,720,975 research outputs found

    Smoking cessation

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    21. Smoking cessation\ud 21.1 Epidemiology of cigarette smoking\ud 21.2 Nicotine, addiction and pharmacokinetics\ud 21.3 Nicotine replacement therapy\ud 21.4 Varenicline\ud 21.5 Bupropio

    Drugs and the autonomic nervous system

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    The nervous systems can initially be divided up into the central and peripheral nervous systems. The central nervous system is the brain and spinal cord and drugs that modify the central nervous system are considered as a subject in systematic pharmacology (therapeutics) section. Everything neural, other that the central nervous system, can be considered peripheral nervous systems. The peripheral nervous systems can be divided into the autonomic(involuntary) nervous system, which is the system that performs without your conscious help, and the somatic or voluntary nervous system, which you can consciously control(Figure 7.1). In addition the autonomic nervous system is divided into the sympathetic and parasympathetic nervous systems..

    Drugs and local chemical mediators

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    <b><font size="2">Contents</font></b>\ud \ud <b>10.1 Histamine and cytokines</b>\ud \ud - 10.1.1 Actions of histamine\ud \ud - 10.1.2 Drugs that modify the actions of histamine\ud \ud - 10.1.3 Cytokines\ud \ud <b>10.2 Eicosanoids</b>\ud \ud - 10.2.1 Cyclooxygenase (COX) and lipooxygenase system\ud \ud - 10.2.2 Actions of eicosanoids\ud \ud - 10.2.3 Drugs that modify the actions of eicosanoids\ud \ud <i>10.2.3.1 Inhibit phospholipase A2\ud </i>\ud \ud <i>10.2.3.2 Non-selective cyclooxygenase inhibitors\ud </i>\ud \ud <i>10.2.3.3 Selective COX-2 inhibitors\ud </i>\ud \ud <i>10.2.3.4 Agonists at prostaglandin receptors\ud </i>\ud \ud <i>10.2.3.5 Leukotriene receptor antagonists</i>\ud \ud <b>10.3. 5-Hydroxtryptamine (serotonin), nitric oxide, and endothelin</b>\ud \ud - 10.3.1 5-HT and migraine\ud \ud - 10.3.2 5-HT and the gastrointestinal tract\ud \ud - 10.3.3 Nitric oxide and angina\ud \ud - 10.3.4 Nitric oxide and erectile dysfunction\ud \ud - 10.3.5 Endothelin and pulmonary hypertensio

    Drugs Used to Treat Endocrine Disorders

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    Introduction to pharmacology, and routes of drugs administration and absorption

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    This eChapter has an introduction to pharmacology and drug nomenclature followed by a detailed discussion of routes of administration starting with oral administration (with absorption from the gastrointestinal tract, and first pass liver metabolism). This is followed by a discussion of rectal, sublingual and injection routes of administration (intravenous, intra-arterial, subcutaneous, intramuscular, intrathecal and epidural). Then the topical, pulmonary and intraosseus routes of administration are considered.\ud \ud <b>Contents</b>\ud \ud 1. Introduction to Pharmacology and Routes of Drug Administration and Absorption of Drugs\ud \ud 1.1 Introduction to Pharmacology\ud \ud 1.2 Drug Nomenclature\ud \ud 1.3 Introduction to drug administration and absorption of drugs\ud \ud 1.4 Routes of drug administration\ud \ud 1.5 Oral administration, absorption from gastrointestinal tract, and first pass liver metabolism\ud \ud 1.6 Rectal\ud \ud 1.7 Sublingual\ud \ud 1.8 Injection\ud \ud 1.8.1 Intravenous\ud \ud 1.8.2 Intra-arterial\ud \ud 1.8.3 Subcutaneous\ud \ud 1.8.4 Intramuscular\ud \ud 1.8.5 Intrathecal\ud \ud 1.8.6 Epidural\ud \ud 1.9 Topical\ud \ud 1.9.1 Skin\ud \ud 1.9.2 Nasal mucosa\ud \ud 1.9.3 Eye \ud \ud 1.9.4 Vaginal\ud \ud 1.10 Pulmonary – Inhalation\ud \ud 1.11 Intraosseu

    Drugs and the peripheral nervous system

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    <b><font size="2">Contents</font></b>\ud \ud <b>7.1. Drugs and the sympathetic nervous system</b>\ud \ud - 7.1.1 The sympathetic nervous system\ud \ud \ud - 7.1.2 Effects of the sympathetic nervous system\ud \ud \ud - 7.1.3 Sympathomimetics\ud \ud \ud - 7.1.4 Selective α1-adrenoceptor antagonists\ud \ud \ud - 7.1.5 β-adrenoceptor antagonists\ud \ud <b>7.2 Drugs and the parasympathetic nervous system</b>\ud \ud - 7.2.1 The parasympathetic nervous system\ud \ud - 7.2.2 Effects of the parasympathetic nervous system\ud \ud - 7.1.3 Muscarinic agonists\ud \ud - 7.1.4 Antimuscarinic agent

    Pharmacodynamics

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    Drug Development

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    Pharmacovigilance, pharmacogenetics and poisoning

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    <b><font size="2">CONTENTS</font></b> \ud \ud <b>5.1 Pharmacovigilance </b>\ud \ud - 5.1.1 Adverse drug effects \ud \ud 5.1.1.1 Types \ud \ud 5.1.1.2 Monitoring of adverse effects \ud \ud - 5.1.2 Adverse drug interactions \ud \ud 5.2.1.1 Pharmacokinetic \ud \ud 5.2.1.2 Pharmacodynamic \ud \ud - 5.1.3 Therapeutic drug monitoring \ud \ud <b>5.2. Introduction to pharmacogenetics</b>\ud \ud - 5.2.1 Enzymes \ud \ud - 5.2.2 Receptor \ud \ud - 5.2.3 Ion channe
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