989 research outputs found
Evaluation of CAN-FD Protocol for Traffic Signalling
U ovom diplomskom radu je evaluiran CAN-FD protokol u svrhu upravljanja prometnom signalizacijom. Naglasak je stavljen na ispitivanje karakteristika protokola u realnim uvjetima te je zbog toga razvijen elektronički modul koji simulira funkcionalnosti LED modula čijim kaskadiranjem se dobiva promjenjivi prometni znak veće površine. Opisane su razlike između CAN 2.0B i CAN-FD protokola te su opisane funkcije pojedinih okvira u jednom CAN-FD paketu. U poglavljima koji se tiču razvoja programske podrške je opisano kako se konfiguriraju generatori signala takta te osnovne inicijalizacije sustava, kao i verifikacija pojedinih segmenata programskog koda. Osim razvoja sklopovlja i programske podrške pokazan je i način odabira adekvatnog mikrokontrolera u smislu karakteristika, kućišta te cijene.In this master thesis author evaluated new CAN-FD communications protocol for use in controlling dynamic traffic signs. Protocol testing was done on a custom made embedded system that simulates the funcionality of a real LED module used in dynamic signs. The differences between CAN-FD and CAN2.0B and the functions are described in the third chapter. Clock configuration and system initialization are described in the chapters regarding development of a software solution for this system as well as testing individual code segments to verify their functionality. In addition to the development of hardware and software this thesis also considers the selection of an adequate microcontroller in terms of characteristics, package and price
Regulation FD: SEC Reestablishes Enforcement Capabilities over Selective Disclosure.
This Recent Development focuses on the potential effects Regulation Fair Disclosure (FD) will have on the participants in the American capital market and on the stock markets themselves. Congress and the Securities Exchange Commission (SEC) seek to achieve confidence in the integrity and fairness of the American stock market and protection of investors from fraud by promoting equal opportunities for investors. In order to maintain a competitive edge, vis-à-vis its foreign counterparts, the United States must continually refine its financial systems to maximize fairness and integrity. This Recent Development focuses on selective disclosure—allowing a limited segment of investors access to information about a company’s financial performance—along with the inability of existing securities regulations to prohibit such practices. The recently promulgated Regulation FD is a measure anticipated to reign in the disclosure of nonpublic information to a privileged few. Specific requirements within the Regulation FD are examined by the author, and the SEC intends for the Regulation FD to level the playing field for investors. Furthermore, this Recent Development addresses potential trouble areas caused by the regulation’s interplay with other securities rules and regulations. In addition to suggestions for compliance, the various touchstones of controversy such as the effects related to Regulation FD on the securities industry are also discussed. Regulation FD molds a remedy to the perceived evils of selective disclosure. Confidentiality agreements represent the SEC’s strategy for controlling selective disclosure, without expressly authorizing it. This Recent Development concludes with an assessment of the practical effects that Regulation FD will have on the securities industry and the likelihood that it is here to stay
A Millimeter-Wave Front-End for FD/FDD Transceivers Featuring an Embedded PA and an N-Path Filter Based Circulator Receiver
This work presents an ultra-compact single-antenna FD/FDD transceivers front-end. It comprises a nonreciprocal circulator, RX, and an integrated power amplifier (PA). In the proposed circulator, we devise a ring quarter-wave transmission line topology with adjusted characteristic impedances to improve TX-to-antenna insertion loss and TX-to-RX isolation. Besides, an AND-gate switching-based N-path filter is proposed to realize the circulator's nonreciprocal gyrator while acting as a mixer-first RX. Owing to the ultra-compact N-path filter structure, the circulator occupies only 0.38mm 2 core area. Over a 27.1-to-31.1GHz band, the realized front-end offers >20dB TX-to-RX isolation while its measured TX-to-antenna insertion loss is 1.7~2.2dB. The RX path tolerates the PA's blocker signal, achieving 5dBm in-band and 13dBm out-of-band B 1dB. Moreover, the PA delivers 15.15dBm peak output power with 33% drain efficiency. Our front-end prototype occupies only 0.7mm 2 , including circulator, PA, quadrature hybrid coupler LO generators, and baseband circuits.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic
Globotrioasylsphingosine levels and optical coherence tomography angiography in fabry disease patients
Background: To date, there are no studies associating the dried blood spot (DBS) levels of globotrioasylsphingosine (lysoGb3) with quantitative optical coherence tomography angiography (OCTA) parameters in Fabry disease (FD) patients. Here, we aimed to investigate the association between OCTA vessel density (VD), vessel length density (VLD) with DBS lysoGb3. Methods: A retrospective, single center analysis of all consecutive FD patients enrolled at the Department of Ophthalmology of the University Hospital of Zurich from December 1st, 2017 to September 9th, 2020. An association between VD and VLD detected by OCTA and lysoGb3 was investigated using a linear mixed model. Results: A total of 57 FD patients (23 male, 34 female; 109 eyes) were included. Forty-one patients suffered from the classic phenotype and 16 from the later-onset phenotype. Lys-oGb3 inversely correlated with VD and VLD in both the superficial (VD: p = 0.034; VLD: p = 0.02) and deep capillary plexus (VD: p = 0.017; VLD: p = 0.018) in the overall FD cohort. Conclusions: Our study shows an association between lysoGb3 and OCTA VD and VLD. This supports the hypothesis that quantitative OCTA parameters might be useful as diagnostic biomarkers for evaluating sys-temic involvement in FD, and possibly other diseases
() Jackknife results for the PD- and FD- libraries: yellow squares indicate hits detected from the PD- library, blue squares indicate hits detected from the FD- library and green squares indicate hits detected from both the libraries
<p><b>Copyright information:</b></p><p>Taken from "Detecting DNA-binding helix–turn–helix structural motifs using sequence and structure information"</p><p>Nucleic Acids Research 2005;33(7):2129-2140.</p><p>Published online 14 Apr 2005</p><p>PMCID:PMC1079965.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p> Incorrectly aligned hits are highlighted with slashes and crosses: forward slashes (/) indicate incorrectly aligned hits detected from the FD- library, backward slashes (\) indicate incorrectly aligned hits detected from the PD- library and crosses (X) indicate incorrectly aligned hits detected from both the libraries. () Jackknife results for the combination of PD- and FD- libraries and the method of 3D-templates. Green squares indicate hits detected from either the FD- library or the PD- library or both; red squares indicate hits detected from the method of 3D-templates; and brown squares indicate hits detected from all the three methods
Risk of screening adherence by category of FD practices.
A. FDs (the markers correspond to the practice baricenter and marker colors to adherence category) plotted against SARs for small triangular areas (about 0.50 km2). B. Top panel: crude adherence rates (left) and (right) by FD practices. Bottom panel: marginal predicted adherence probability for low adherence FDs and high participation FDs and, for comparison, adherence probability for a generic person at average level of covariates. Figure was created by the author Bianconi F. combing the caterpillar, bar plots and maps generate with GeCO-sys an extension of [21].</p
sj-pdf-2-jrs-10.1177_01410768231205430 - Supplemental material for Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study
Supplemental material, sj-pdf-2-jrs-10.1177_01410768231205430 for Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study by Ruby SM Tsang, Utkarsh Agrawal, Mark Joy, Rachel Byford, Chris Robertson, Sneha N Anand, William Hinton, Nikhil Mayor, Debasish Kar, John Williams, William Victor, Ashley Akbari, Declan T Bradley, Siobhan Murphy, Dermot O’Reilly, Rhiannon K Owen, Antony Chuter, Jillian Beggs, Gary Howsam, Aziz Sheikh, FD Richard Hobbs and Simon de Lusignan in Journal of the Royal Society of Medicine</p
sj-pdf-1-jrs-10.1177_01410768231205430 - Supplemental material for Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study
Supplemental material, sj-pdf-1-jrs-10.1177_01410768231205430 for Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study by Ruby SM Tsang, Utkarsh Agrawal, Mark Joy, Rachel Byford, Chris Robertson, Sneha N Anand, William Hinton, Nikhil Mayor, Debasish Kar, John Williams, William Victor, Ashley Akbari, Declan T Bradley, Siobhan Murphy, Dermot O’Reilly, Rhiannon K Owen, Antony Chuter, Jillian Beggs, Gary Howsam, Aziz Sheikh, FD Richard Hobbs and Simon de Lusignan in Journal of the Royal Society of Medicine</p
Estimating the fundamental diagram using moving observers
The fundamental diagram (FD) describes the relation between the flow and density in equilibrium conditions. In this paper, we propose an estimation approach to estimate the FD based on data from moving observers. This approach consists of two main steps: (1) estimate flow and density for space-time areas based on trajectories of moving observers and the times and locations they are overtaken or being overtaken and (2) estimate the FD based on the fflow,densityg-estimates. To evaluate and gain a deeper understanding of the proposed approach, a simulation study was conducted. This study shows that the fflow,densityg-estimates provide valuable information to estimate the FD. Furthermore, the FDs belonging to the simulated traffic flow are estimated accurately. We realize that the second step is expected to be less accurate for traffic that behaves stochastic. Therefore, we provide a potential solution path to extend the second step in future work.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Transport and PlanningTransport and Plannin
Application-Layer Anomaly Detection Leveraging Time-Series Physical Semantics in CAN-FD Vehicle Networks
Data Availability Statement:
The data presented in this study are available on request from the corresponding author. The data are not publicly available due to the need for confidentiality of application layer protocols for car companies.The Controller Area Network with Flexible Data-Rate (CAN-FD) bus is the predominant in-vehicle network protocol, responsible for transmitting crucial application semantic signals. Due to the absence of security measures, CAN-FD is vulnerable to numerous cyber threats, particularly those altering its authentic physical values. This paper introduces Physical Semantics-Enhanced Anomaly Detection (PSEAD) for CAN-FD networks. Our framework effectively extracts and standardizes the genuine physical meaning features present in the message data fields. The implementation involves a Long Short-Term Memory (LSTM) network augmented with a self-attention mechanism, thereby enabling the unsupervised capture of temporal information within high-dimensional data. Consequently, this approach fully exploits contextual information within the physical meaning features. In contrast to the non-physical semantics-aware whole frame combination detection method, our approach is more adept at harnessing the physical significance inherent in each segment of the message. This enhancement results in improved accuracy and interpretability of anomaly detection. Experimental results demonstrate that our method achieves a mere 0.64% misclassification rate for challenging-to-detect replay attacks and zero misclassifications for DoS, fuzzing, and spoofing attacks. The accuracy has been enhanced by over 4% in comparison to existing methods that rely on byte-level data field characterization at the data link layer.National Natural Science Foundation of China under Grants 52202494 and 52202495
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