28 research outputs found
Topologically Overlapped Fused LASSO Measure for Reconstructing Gene Regulation Networks
No full textIdentifying target genes in Gene Regulation Network (GRN) models has always been challenging in Systems Biology. In this regard, indirect gene regulatory hierarchical architectures may be promising enough, considering varied topological structures and unknown gene regulation factors. Such causal regulations can be investigated, keeping in force all perturbation experiments of a dataset. Contemporary research primarily highlights direct interaction networks, which mostly forego the inevitable presence of a third entity, if any, towards varied forms of causal regulations. In this article, we have developed a hierarchical algorithm that unveils the genetic wiring through the Fused Least Absolute Shrinkage and Selection Operator (Fused-LASSO) technique with a Topological Overlap (TO) measure as the interaction structure. The potential power of this proposed model is studied over YEAST Cell Cycle, and Human cancer cell line data (HeLa). In this connection, the different statistically significant hierarchical regulation outcomes maintaining parity with the direct interaction structures, if any, to the target genes may throw new light on gene regulation statistics.</p
Structural and Piezoelectric Properties of (Ba1-xCaxZr0.1Ti0.9)O3 Ceramics, Near Morphotropic Phase Boundary (0.140 ≤ x ≤ 0.160)
Get PDF111-116Ceramic pellet samples of (Ba1-xCaxZr1-yTiy)O3 (x = 0.140- 0.160, y = 0.9), were prepared using the conventional solidstate
reaction method followed by double sintering. Structural and piezoelectric measurements of the prepared compositions
were carried out at room temperature. For the compositions with x ≤ 0.150, the converse piezoelectric constant (d33*), strain
(%), coercive field (Ec) and remnant polarization (Pr), were found increasing with x, which were found anomalously to
decrease with further increase in x above 0.150. Among the prepared compositions, maximum value of d33* was found
342 pm/V, for the samples with x = 0.150. The measured maximum values of strain (%), piezoelectric constant (d33*) and
break in XRD peak shifting patterns of the prepared samples indicate composition dependent piezoelectric properties,
showing morphotropic- like phase boundary (MPB), near x = 0.150 composition. The prepared compositions of lead- free
BCZT ceramics will extend the possibilities to use this compound in the field of piezoelectric sensors
A Composite Mode Differential Gene Regulatory Architecture based on Temporal Expression Profiles
No full textMeasuring Real-Time Road Traffic Queue Length: A Reliable Approach Using Ultrasonic Sensor
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Identification of The Important Volatile Organic Component in Cardamom based on Silica-Modified Piezoelectric Resonator
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