738 research outputs found

    Thermostable engineered enzyme

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    The invention relates to an engineered PETase enzyme comprises an amino acid sequence having at least 70% or 80%, 90%, 95%, 99% or 100% sequence identity to SEQ ID NO.1. Preferably, the PETase enzyme comprises SEQ ID NO.1 with at least four mutations. The invention also refers to a composition and to a method for decomposing plastics

    Inlist files for "Detectability of axisymmetric magnetic fields from the core to the surface of oscillating post-main sequence stars"

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    <p>Concerned article: "Detectability of axisymmetric magnetic fields from the core to the surface of oscillating post-main sequence stars" by Bhattacharya et al. (submitted).<br>Corresponding author: Shatanik Bhattacharya</p> <p>Inlists for the proof-of-concept stellar models used in this project have been provided here for reproducibility.</p> <p>For the red-giant model, the inlist was executed with MESA version r22.05.1 and MESA-SDK version x86 64-linux-22.6.1. Model 500 (age 4.056 Gyr) was used as the RG in this project.</p> <p>For the sub-giant models, the inlist was executed with MESA version r23.05.1 and MESA-SDK version x86 64-linux-22.6.1. Models 345 (age 3.624 Gyr) and 350 (age 3.702 Gyr) were used as the MSG and LSG models respectively.</p&gt

    Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition

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    Fructosyl peptide oxidases (FPOX) are deglycating enzymes that find application as key enzymatic components in diabetes monitoring devices. Indeed, their use with blood samples can provide a measurement of the concentration of glycated hemoglobin and glycated albumin, two well-known diabetes markers. However, the FPOX currently employed in enzymatic assays cannot directly detect whole glycated proteins, making it necessary to perform a preliminary proteolytic treatment of the target protein to generate small glycated peptides that can act as viable substrates for the enzyme. This is a costly and time consuming step. In this work, we used an in silico protein engineering approach to enhance the overall thermal stability of the enzyme and to improve its catalytic activity toward large substrates. The final design shows a marked improvement in thermal stability relative to the wild type enzyme, a distinct widening of its access tunnel and significant enzymatic activity towards a range of glycated substrates

    Fables for All Ages

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    Tagore is a favorite author for me as a writer of poems bearing on the spiritual life. I was thus surprised to see him presented as a writer of fables. Alas, I fear that what is in this paperback book is not fables as I understand "fable." A T of C would have helped me realize that there are three longer works here, perhaps short stories or Novellen. I have to save enjoying them for a later time. For now, I include the book in the collection as a help to me and others who may expect something different from the book's title.Abanindranath Tagore, translated biy Manoshi Bhattachary

    Author′s reply

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    Studying Human Relationships in the Short Stories of Bhabani Bhattacharya

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    Bhabani Bhattacharya is a kind of author who writes mostly on human relationships. In Steel Hawk and other Stories which were published in 1968 there are various such kind of stories. His themes are traditional but new because he has a different and innovative way of writing. His characters are also very interesting and they are influenced from real human societies. This realistic and idealistic approach is very uncommon. In A moment of Eternity we can see a fine blend of realism and idealism. This shows that how he uses the traditional human values as a raw material for his short stories. His experiments with traditional values of life are full of new possibilities and hopes. In some cases we can also find that his characters are alienated and repressed but still there is some sense of optimism in their lives. If they reflect pessimism then this can be a chance of learning for readers. Bhabani Bhattacharya believes that a writer must not impose his school of thoughts on his readers. So in his short stories readers are free to analyze the different situations of life. The story like public figure shows that how a man can change in life. This changing is not normal as it can lead him to identity crisis which can be painful. After reading his short stories we can easily locate that there is a kind of synthesis between modernism and traditionalism in most of his writings. Stories like the steel hawk, The Acrobats , Names are not table’s and the quack are noteworthy as they reflect real life situations. They are not simply stories but they present the way by which life can treat an individual. It also shows a better craftsmanship of the author

    The Impossible Demands of Nabarun Bhattacharya

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    This article aims at understanding the character of ‘Fyataru’ that the Bengali author Nabarun Bhattacharya created. This character returns again and again in many of Nabarun’s stories and novels. It is an important signifier of Nabarun’s literary vision, since it represents the politics of dissent that the author believed in most prominently. Through the dissection of the fictional Fyataru, this article aims to understand the politics that guided Nabarun’s writings. It also tries to determine the philosophy behind this journey of fiction, the history of Nabarun’s thought, as well as its broader implications in contemporary reality. Reading Nabarun’s literature in the light of the theory of anarchism illuminates the purpose of  Fyataru, and how this fictional creature can identify its own reflection in individuals of today’s society who have tried to rebel against institutional oppression with the weapon of anarchist practices. Julian Assange, Edward Snowden, and other underground activists may well be considered as such anarchists. The article also attempts to understand why anarchy is an essential element in a society regulated by governments, capitalist institutions and corporate powers. It aims to establish that anarchy protects the freedom of expression from being thwarted by populist hegemony, and therefore protects the right of the individual to free thought and dissent. The only instrument that can prevent dominant opinions from marginalizing and throttling the formation of free ideas is subversion, and the Fyatarus of Nabarun’s literature are the harbingers of such subversion

    The Impossible Demands of Nabarun Bhattacharya

    No full text
    This article aims at understanding the character of ‘Fyataru’ that the Bengali author Nabarun Bhattacharya created. This character returns again and again in many of Nabarun’s stories and novels. It is an important signifier of Nabarun’s literary vision, since it represents the politics of dissent that the author believed in most prominently. Through the dissection of the fictional Fyataru, this article aims to understand the politics that guided Nabarun’s writings. It also tries to determine the philosophy behind this journey of fiction, the history of Nabarun’s thought, as well as its broader implications in contemporary reality. Reading Nabarun’s literature in the light of the theory of anarchism illuminates the purpose of  Fyataru, and how this fictional creature can identify its own reflection in individuals of today’s society who have tried to rebel against institutional oppression with the weapon of anarchist practices. Julian Assange, Edward Snowden, and other underground activists may well be considered as such anarchists. The article also attempts to understand why anarchy is an essential element in a society regulated by governments, capitalist institutions and corporate powers. It aims to establish that anarchy protects the freedom of expression from being thwarted by populist hegemony, and therefore protects the right of the individual to free thought and dissent. The only instrument that can prevent dominant opinions from marginalizing and throttling the formation of free ideas is subversion, and the Fyatarus of Nabarun’s literature are the harbingers of such subversion.   Keywords: Anarchism; Subversion; Journalism; Nabarun

    Fyataru and Subaltern War Cries: Nabarun Bhattacharya and the Rebirth of the Subject

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    Nabarun Bhattacharya, the radical literary voice of Bengal demonstrates notions of dissidence and aesthetic Bolshevism. His fictive dissenting subjects, the fyatarus typify rebellious roles in a post-ideological era when complicity and conformity are rewarded as the norm. Nabarun`s  literary crusade interrogates the status quo and composes counter-currents of subjectivities. As a revolutionary saboteur he redefined the mode of subaltern representation by scripting the prose of counter insurgency through literature. The present excursus pays homage to this noted maverick writer of dissidence and attempts an analysis of the singularity of Nabarun`s fictional domain with specific references to some of his best known fictional works which constitute and explicate his prototypical subaltern anti-heroes such as fyatarus and Choktars who emerge as brilliant metaphorisation of dissent and disgust at our contemporary socio-political praxis. While the popular literary trends of the day have colluded with the hegemonic narrative of global capital that prevents the litterateur to coronate revolutionary anarchism or insurgency, Nabarun has consistently caused epistemic tremors through his overt advocacy of radical violence and systemic change.   Keywords: Nabarun Bhattacharya; Author as Saboteur; Subaltern; radical    violence; literary Bolshevism

    Ghosts, Drunkards and Bad Language:: Translating the Margins of Nabarun Bhattacharya\u27s Kāṅāl Mālsāṭ (‘The War Cry of the Beggars’)

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    This article unfolds some problematic aspects encountered during the translation of Nabarun Bhattacharya\u27s radical novel Kāṅāl Mālsāṭ (2003), published in Italian with the title Gli ammutinati di Calcutta (2016). I focus on the translation of the language of the margins, intended as social, ontological as well as linguistic spaces. The difficulty of translating into Italian the richness of Bengali slang in the semantic field of boozing offers an interesting case to reveal the strategies of a radical translation practice, which resists domestication (Venuti; Spivak) and endorses the unsettling use of sub-standard language(s) in order to translate the bizarre mutiny of Kāṅāl Mālsāṭ and the counter-language of its author
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