10 research outputs found

    Model and Data-Driven Combination: A Fault Diagnosis and Localization Method for Unknown Fault Size of Quadrotor UAV Actuator Based on Extended State Observer and Deep Forest

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    The rotor is an essential actuator of quadrotor UAV, and is prone to failure due to high speed rotation and environmental disturbances. It is difficult to diagnose rotor faults and identify the fault localization simultaneously. In this paper, we propose a fault diagnosis and localization scheme based on the Extended State Observer (ESO) and Deep Forest (DF). This scheme can accurately complete the fault diagnosis and localization for the quadrotor UAV actuator without knowing the fault size by combining the model-based and the data-driven methods. First, we obtain the angular acceleration residual signal of the quadrotor UAV by using ESO. The residual signal is the difference between the observed state of ESO and the true fault state. Then, we design the residual feature analysis method by considering the position distribution of the quadrotor UAV actuator. This method can embed the actuator fault localization information into the fault data by simultaneously considering pitch and roll of the quadrotor UAV. Finally, we complete the fault diagnosis and localization of the quadrotor UAV actuator by processing the fault data by using DF. This scheme has the advantages of straightforward observer modeling, strong generalization ability, adaptability to small sample data, and few hyperparameters. Our simulation results indicate that the accuracy of the proposed scheme reaches more than 99% for the unknown size of the quadrotor UAV actuator fault

    Quantifying the heterogeneous impacts of the urban built environment on traffic carbon emissions: New insights from machine learning techniques

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    The configuration of the urban built environment is critical for promoting sustainability and achieving carbon neutrality. However, existing studies mostly use linear and spatial econometric models to investigate the relationship between urban built environments and traffic carbon dioxide (CO2) emissions, in-depth studies exploring the heterogeneous impacts of related features on traffic CO2 emission by interpretive machine learning models are scarce. Hence, we extract four dimensionless features to depict the size, compactness, irregularity, and isolation of built-up areas, and road network-related features (i.e., average cluster coefficient, road topological density, and road geometric density), respectively. Subsequently, we develop an interpretive machine learning framework based on the extracted features related to the urban built-up areas and road networks. The interpretive results of the proposed framework uncover that urban morphological features, especially population density (POP), GDP per capita (GDPpc), and urban physical compactness (UPC), have a heterogeneous impact on the per capita traffic emission (PCCE) across different cities. GDPpc is more like a linear relationship with PCCE, and UPC has a significant influence on PCCE when its value is between 62% and 78%. Our results also reveal the nonlinear relationships and interactive effects between these features, providing the implications of urban morphological planning and carbon emission reduction.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Transport and Plannin

    Specific Heat Capacities of Two Functional Ionic Liquids and Two Functional Deep Eutectic Solvents for the Absorption of SO2

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    The specific heat capacities (C-p) of four absorbents (1,1,3,3-tetramethlylguanidinium lactate, monoethanolammonium lactate, betaine-ethylene glycol, and L-carnitine-ethylene glycol), which can chemically absorb sulfur dioxide (SO2) with low concentrations, were measured by a Calvet BT 2.15 calorimeter in a temperature range of 318.15 K-363.15 K. The measured specific heat capacities as a function of temperature were correlated with a second-order empirical polynomial equation. The result indicates that the equation can accurately fit the measured specific heat capacities. All the measured specific heat capacities increase with increasing temperature. 1,1,3,3-Tetramethlylguanidinium lactate has the lowest specific heat capacity. The measured specific heat capacities of the four absorbents are lower than that of water, which is beneficial to the desulfurization process.National Natural Science Foundation of China [21176020, 21306007]; Ministry of Finance; Ministry of Education of PRC (BUCT)SCI(E)ARTICLE92708-27126

    The politics of fashion: perceptions of power in female clothing and ornamentation as reflected in the sixteenth-century Chinese novel Jin Ping Mei

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    This thesis examines issues of female power and influence in sixteenth-century China focusing on how women and their roles were perceived in the changing social environment of the mid-late Ming dynasty. Using aspects of a New Historicist approach, information from contemporary literary and historical sources are analysed alongside each other. With its emphasis on the lives of women and preoccupation with the description of material objects, the late Ming novel Jin Ping Mei forms an important element in the thesis. China in the sixteenth century saw expanding urbanisation, the emergence of a new wealthy merchant class, increasing visibility of women and a questioning of traditional morality. Fashion consciousness, as one of the most conspicuous aspects of the new material culture, is a possible indicator of these trends. Traditional Western theories contend that fashion began in the particular context of Renaissance Europe. However, this study argues that a similar fashion awareness existed in China too, and was manifested in a competitive striving for social status, in this case specifically among women. In contrast to previous studies which downplayed the impact women had on defining traditional Chinese culture, this thesis demonstrates how women and their sartorial choices began to redefine the boundaries of material culture, influencing literati discourse which, in turn, re- influenced female behaviour

    A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3KLHL22

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    Abstract The CUL3-RING E3 ubiquitin ligases (CRL3s) play an essential role in response to extracellular nutrition and stress stimuli. The ubiquitin ligase function of CRL3s is activated through dimerization. However, how and why such a dimeric assembly is required for its ligase activity remains elusive. Here, we report the cryo-EM structure of the dimeric CRL3KLHL22 complex and reveal a conserved N-terminal motif in CUL3 that contributes to the dimerization assembly and the E3 ligase activity of CRL3KLHL22. We show that deletion of the CUL3 N-terminal motif impairs dimeric assembly and the E3 ligase activity of both CRL3KLHL22 and several other CRL3s. In addition, we found that the dynamics of dimeric assembly of CRL3KLHL22 generates a variable ubiquitination zone, potentially facilitating substrate recognition and ubiquitination. These findings demonstrate that a CUL3 N-terminal motif participates in the assembly process and provide insights into the assembly and activation of CRL3s

    DataSheet_1_Radiomics in Oncology: A 10-Year Bibliometric Analysis.pdf

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    ObjectivesTo date, radiomics has been applied in oncology for over a decade and has shown great progress. We used a bibliometric analysis to analyze the publications of radiomics in oncology to clearly illustrate the current situation and future trends and encourage more researchers to participate in radiomics research in oncology.MethodsPublications for radiomics in oncology were downloaded from the Web of Science Core Collection (WoSCC). WoSCC data were collected, and CiteSpace was used for a bibliometric analysis of countries, institutions, journals, authors, keywords, and references pertaining to this field. The state of research and areas of focus were analyzed through burst detection.ResultsA total of 7,199 pieces of literature concerning radiomics in oncology were analyzed on CiteSpace. The number of publications has undergone rapid growth and continues to increase. The USA and Chinese Academy of Sciences are found to be the most prolific country and institution, respectively. In terms of journals and co-cited journals, Scientific Reports is ranked highest with respect to the number of publications, and Radiology is ranked highest among co-cited journals. Moreover, Jie Tian has published the most publications, and Phillipe Lambin is the most cited author. A paper published by Gillies et al. presents the highest citation counts. Artificial intelligence (AI), segmentation methods, and the use of radiomics for classification and diagnosis in oncology are major areas of focus in this field. Test-retest statistics, including reproducibility and statistical methods of radiomics research, the relation between genomics and radiomics, and applications of radiomics to sarcoma and intensity-modulated radiotherapy, are frontier areas of this field.ConclusionTo our knowledge, this is the first study to provide an overview of the literature related to radiomics in oncology and may inspire researchers from multiple disciplines to engage in radiomics-related research.</p

    DataSheet_2_Radiomics in Oncology: A 10-Year Bibliometric Analysis.xlsx

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    ObjectivesTo date, radiomics has been applied in oncology for over a decade and has shown great progress. We used a bibliometric analysis to analyze the publications of radiomics in oncology to clearly illustrate the current situation and future trends and encourage more researchers to participate in radiomics research in oncology.MethodsPublications for radiomics in oncology were downloaded from the Web of Science Core Collection (WoSCC). WoSCC data were collected, and CiteSpace was used for a bibliometric analysis of countries, institutions, journals, authors, keywords, and references pertaining to this field. The state of research and areas of focus were analyzed through burst detection.ResultsA total of 7,199 pieces of literature concerning radiomics in oncology were analyzed on CiteSpace. The number of publications has undergone rapid growth and continues to increase. The USA and Chinese Academy of Sciences are found to be the most prolific country and institution, respectively. In terms of journals and co-cited journals, Scientific Reports is ranked highest with respect to the number of publications, and Radiology is ranked highest among co-cited journals. Moreover, Jie Tian has published the most publications, and Phillipe Lambin is the most cited author. A paper published by Gillies et al. presents the highest citation counts. Artificial intelligence (AI), segmentation methods, and the use of radiomics for classification and diagnosis in oncology are major areas of focus in this field. Test-retest statistics, including reproducibility and statistical methods of radiomics research, the relation between genomics and radiomics, and applications of radiomics to sarcoma and intensity-modulated radiotherapy, are frontier areas of this field.ConclusionTo our knowledge, this is the first study to provide an overview of the literature related to radiomics in oncology and may inspire researchers from multiple disciplines to engage in radiomics-related research.</p

    Variability in the vertical hyporheic water exchange affected by hydraulic conductivity and river morphology at a natural confluent meander bend

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    River confluences and their associated tributaries are key morphodynamic nodes that play important roles in controlling hydraulic geometry and hyporheic water exchange in fluvial networks. However, the existing knowledge regarding hyporheic water exchange associated with river confluence morphology is relatively scarce. On January 14 and 15, 2016, the general hydraulic and morphological characteristics of the confluent meander bend (CMB) between the Juehe River and the Haohe River in the southern region of Xi'an City, Shaanxi Province, China, were investigated. The patterns and magnitudes of vertical hyporheic water exchange (VHWE) were estimated based on a one-dimensional heat steady-state model, whereas the sediment vertical hydraulic conductivity (K-v) was calculated via in situ permeameter tests. The results demonstrated that 6 hydrodynamic zones and their extensions were observed at the CMB during the test period. These zones were likely controlled by the obtuse junction angle and low momentum flux ratio, influencing the sediment grain size distribution of the CMB. The VHWE patterns at the test site during the test period mostly showed upwelling flow dominated by regional groundwater discharging into the river. The occurrence of longitudinal downwelling and upwelling patterns along the meander bend at the CMB was likely subjected to the comprehensive influences of the local sinuosity of the meander bend and regional groundwater discharge and finally formed regional and local flow paths. Additionally, in dominated upwelling areas, the change in VHWE magnitudes was nearly consistent with that in K-v values, and higher values of both variables generally occurred in erosional zones near the thalweg paths of the CMB, which were mostly made up of sand and gravel. This was potentially caused by the erosional and depositional processes subjected to confluence morphology. Furthermore, lower K-v values observed in downwelling areas at the CMB were attributed to sediment clogging caused by local downwelling flow. The confluence morphology and sediment K-v are thus likely the driving factors that cause local variations in the VHWE of fluvial systems

    Global, regional, national, and local burden of COVID‐19 with inequality analysis across 920 locations, 2020–2021

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    Although the COVID‐19 pandemic has profoundly reshaped global health systems, a comprehensive and standardized quantification of its direct health burden across multiple spatial scales, particularly during its initial and most severe phases in 2020 and 2021, has remained lacking. Here, we present the first global‐to‐local estimation of the direct COVID‐19 burden during this period based on a repeated cross‐sectional design and secondary analysis of population‐level data using the Global Burden of Disease (GBD) 2021 analytical framework. We evaluated key measures of health burden for each year separately and assessed temporal changes to capture evolving patterns and disparities across 920 locations spanning five spatial hierarchies: global, regional, national, subnational, and local. The analysis includes 204 countries and territories, 77 international regions (e.g., the Commonwealth), 20 subnational regions (e.g., North England), and 618 local units (e.g., London). By integrating coarse‐grained (e.g., global and regional) and fine‐grained (e.g., national and local) estimates, we identified substantial spatial and socioeconomic inequalities in incidence, prevalence, mortality, disability‐adjusted life years (DALYs), years lived with disability (YLDs), and years of life lost (YLLs). Both age‐standardized and age‐, sex‐, and location‐specific estimates were generated. Leveraging the robust epidemiological modeling capabilities of the GBD framework, along with inequality metrics, including the slope index of inequality (SII) and the concentration index of inequality (CII), we uncovered pronounced disparities not only across countries and regions but also within them. Our findings underscore that aggregated regional data could mask potentially substantial cross‐national disparities and national aggregates could similarly obscure subnational and local differences. This has profound implications for understanding the distribution of long COVID risk, improving pandemic preparedness, and guiding equitable public health policy. Ultimately, this study provides an unprecedented evidence base to inform global‐to‐local health system strengthening and support data‐driven equity‐focused responses to future public health emergencies

    Identifying potential vulnerability to long COVID through global‐to‐local inequalities in years lived with disability attributed to COVID‐19, 2020–2021, across 920 locations

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    The COVID‐19 pandemic has reshaped global health; however, the long‐term burden of long COVID remains poorly understood, especially in low‐ and middle‐income countries (LMICs), where limited surveillance and data gaps may obscure a substantial and sustained impact. Using the Global Burden of Disease (GBD) 2021 framework, we previously assessed the direct COVID‐19 burden—including incidence, prevalence, mortality, and disability‐adjusted life‐years (DALYs)—across 920 locations during 2020–2021. In this study, we focus on years lived with disability (YLDs), particularly in 2021, as a potential early indicator to identify locations and populations that may be at higher risk of long COVID burden in subsequent years (e.g., 2022–2023). We also examine patterns of inequality to highlight vulnerable groups. Our findings are consistent with multiple large‐scale studies on long COVID and suggest that YLDs may serve as a useful early proxy for ongoing burden. Importantly, we identify notably higher age‐standardized YLD rates in LMICs—especially in Sub‐Saharan Africa and in parts of South Asia and Eastern Europe. These areas, previously underexplored in long COVID research, might be particularly susceptible to its effects. Among the top 10 countries with the highest age‐standardized YLD rates in 2021, 80% fell within the low, low‐middle, and middle Socio‐demographic Index (SDI) categories. These high age‐standardized YLD rates may point to systemic vulnerabilities and entrenched structural health disparities, indicating a potential for considerable and enduring long COVID burden that could persist to the present day in the absence of targeted interventions. Furthermore, our inequality analysis underscores that while both advantaged and disadvantaged groups in LMICs require attention, the most disadvantaged groups warrant special focus due to their more severe resource constraints and restricted capacity for resilience‐building. Overall, this study supports calls for stronger surveillance, expanded access to rehabilitation, and better integration of long COVID care into universal health coverage. Continued GBD updates will be essential for monitoring trends and guiding responsive public health strategies
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