86,698 research outputs found
The effects of recreational activities on wild mammals
No full textAn increasing number of people practise nature-based recreational activities, generating great economic resources, which can become a threat to wildlife species, because wild animals may perceive human presence as a predation risk. Many studies have investigated the effects induced in wild mammals by nature-based recreation. Despite that, a thorough overview of the literature focused on this topic is lacking. We conducted a broad bibliographic search, reviewed 209 articles, and identified 672 case studies about the effect of recreational activities on terrestrial mammals. We hypothesised behavioural metrics, disturbance sources and protocols of data collection affect the probability of detecting the effect of recreational activities. We highlighted this research topic is affected by huge bias both on a taxonomical and geographical level. Studies were mostly carried out in North America or Europe and almost 90 % of them focused on Cetartiodactyla, Carnivora, and Rodentia. Nevertheless, trends in publication rates suggest that these biases are declining. Using multiple regression, we examined the study designs to understand which features were linked with a higher probability of detecting a disturbance. Although studies measuring physiological responses are scarce in the literature, these seem to be more likely to detect disturbances than behavioural ones. Studies implemented on individually recognisable animals are associated with a higher likelihood of detecting the effects of the disturbance. Harnessing this knowledge, future studies could generate a better understanding of the effects of recreational activities. Adopting suitable study protocols is essential for efficiently managing economic resources in scientific research and can help define better conservation strategies
Venous and arterial thromboembolic events with immune checkpoint inhibitors: A systematic review
No full textBackground: Venous (VTEs) and arterial thromboembolic events (ATEs) are causes of morbidity, disability, mortality, and increase in treatment costs in cancer patients. The risk associated with immune checkpoint inhibitors (ICIs) has not yet been clarified. The primary objective of this systematic review was to evaluate the incidence of VTEs and ATEs in patients treated with ICIs as single agents or in combination with other treatments. Material and methods: Data from retrospective and prospective studies were selected from PubMed, EMBASE, SCOPUS, and The Cochrane Library from inception up to May up to 21st May 2020. All studies had to be in English and use human study participants. The studies were eligible if they provided a number (or rate) of VTEs and ATEs and the size of the population included. The PRISMA guidelines were followed. The data on the incidence of VTEs and ATEs were extracted for each arm, analyzed using random-effects models, and reported as weighted measures. Results: A total of 20,273 patients from 68 studies were included (median follow-up ranged from a few months up to three years). Overall, there were 390 VTEs and 59 ATEs, with incidence rates of 2.7% (95%CI 1.8%–4%) and 1.1% (95%CI 0.5%–2.1%), respectively. The rate of pulmonary embolism was 1.6% (95%CI 0.7%–3.2%) and deep venous thrombosis was 2.7% (95%CI 1.4%–5.4%). In studies where ICIs were administered with chemotherapy, rates of VTEs were similar to ICI alone arms (2.8% vs 2.5%). The rate of stroke and myocardial infarction were 1.1% (95%CI 0.65%–1.45%) and 0.7% (95%CI 0.15%–1.15%), respectively. In randomized trials, compared with non-ICIs containing arms (e.g. chemotherapy), the relative risk (RR) of VTEs due to ICIs was similar (RR 1.08, 95%CI 0.6–1.9; P =.79). Conclusions: Thromboembolic events associated with ICIs are relatively rare in cancer patients with an advanced stage of the disease. However, in randomized studies, their incidence is similar to control arms, suggesting that the contributory role of ICIs to the thromboembolic risk in many cancer settings is small
EmbTrack: A Wearable IEEE 802.15.4 Tracking System for Logistics
No full textWe present an innovative wireless embedded system for logistic applications: it is a prototype of a portable appliance to manage operations in production activity. The system is based on a wearable device which is able to read products codes and allows the system to guide users through the different phases of warehouse's everyday life; by means of wireless IEEE 802.15.4 standard – on the ISM 2.4 GHz band – the system can transfer data, service and control messages and commands to and from its coupled management server.Moreover by an ad-hoc procedure based on a Weighted Minimum Mean Square Error (W-MMSE) localization algorithm, the system is able to localize users within a typical logistic scenario. The system is addressed to retail markets, pharmacies, porterage and logistic activities thus allowing the user to work more efficiently and employing mobile a more ergonomic terminal: from intensive picking to packing, from load of goods from lines to lists and warehouse checks
A wearable IEEE 802.15.4 system for logistics scenarios
No full textWe present a novel and innovative wireless embedded system for logistic applications: it is a prototype of a portable appliance to manage operations in production activity. The system is based on a wearable device which is able to read products codes and allows the system to guide users through the different phases of warehouse's everyday life; by means of IEEE 802.15.4 standard – on the ISM 2.4 GHz band – the system can wirelessly transfer data, service and control messages and commands to and from its coupled management server. The system is addressed to retail markets, pharmacies, porterage and logistic activities and it allows the user to work more efficiently and with a mobile terminal that is more ergonomic: from intensive picking to packing, from load of goods from lines to lists and warehouse checks
A Wireless Wearable Embedded System for Logistics Based On IEEE 802.15.4.
No full textIn this paper we present the new prototype of a portable appliance to be used for logistic operations in production warehouses. It is based on a novel and innovative wireless embedded system able to read products codes; it can also guide users through the different phases of warehouse's everyday life; the system can wirelessly transfer data, service and control/command messages to and from its coupled system server. Retail markets, pharmacies, transport and logistic activities are preferred application environments. From intensive picking to packing, from load of goods from lines to lists and warehouse checks, this system enables the user to work more efficiently and ergonomically
Bilateral subthalamic deep brain stimulation in a patient with Parkinson's disease who had previously undergone thalamotomy and autologous adrenal grafting in the caudate nucleus: Case report
No full textFIGURE 3. Hyalella longipropodus n in A new species of freshwater amphipod (Crustacea, Peracarida, Hyalellidae) from Southern Brazil
No full textFIGURE 3. Hyalella longipropodus n. sp., Palmeira das Missões municipality, state of Rio Grande do Sul, Southern Brazil. Paratype, male. (A) habitus; (B) antenna 1; (C) antenna 2; (D) mandible; (E) upper lip; (F) Lower lip; (G) maxilla 1; (H) maxilla 2; (I) maxilliped. Scales: 0.65 mm for 2A; 0.5 mm for 2B, C; 0.2 mm for 2D–I.Published as part of Limberger, Marcio, Castiglioni, Daniela Da Silva & Graichen, Daniel Ângelo Sganzerla, 2021, A new species of freshwater amphipod (Crustacea, Peracarida, Hyalellidae) from Southern Brazil, pp. 182-200 in Zootaxa 5026 (2) on page 187, DOI: 10.11646/zootaxa.5026.2.2, http://zenodo.org/record/527082
FIGURE 5. Hyalella longipropodus n in A new species of freshwater amphipod (Crustacea, Peracarida, Hyalellidae) from Southern Brazil
No full textFIGURE 5. Hyalella longipropodus n. sp. Limberger, Graichen & Castiglioni, Palmeira das Missões municipality, state of Rio Grande do Sul, Southern Brazil. Paratype, male. (A) peraeopod 3; (B) peraeopod 4; (C) peraeopod 5; (D) peraeopod 6; (E) peraeopod 7; (F) pleopod. Scales 4A to 4E—0.5 mm; 4F—0.2 mm.Published as part of Limberger, Marcio, Castiglioni, Daniela Da Silva & Graichen, Daniel Ângelo Sganzerla, 2021, A new species of freshwater amphipod (Crustacea, Peracarida, Hyalellidae) from Southern Brazil, pp. 182-200 in Zootaxa 5026 (2) on page 189, DOI: 10.11646/zootaxa.5026.2.2, http://zenodo.org/record/527082
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Risk factors for late posttraumatic epilepsy
No full textThe usually accepted risk factors for late post-traumatic seizures (LPTS) are those identified years ago by Jennet: early post-traumatic seizure (EPTS), depressed fracture, intracranial haematoma. Prolonged unconsciousness (PTA greater than 24 hrs) is another factor usually added. More recently, personal experience of the Authors and the data of the literature, compel us to question the validity of known risk factors based on clinical data. Authors believe that the identification of patients at risk for LPTS depends mainly on the precise definition of trauma severity and on CT or surgically documented lesions of brain substance. Three groups of patients, characterized by the presence of one or more of the accepted risk factors of LPTS, have been studied. In our experience, while in adults the presence of documented cortico-subcortical lesions represents the main risk factor of LPTS, in children the appearance of EPTS per se increases the risk of LPTS, irrespective of the presence of documented brain lesions. Alteration of consciousness without a focal lesion, even if prolonged and severe, is not a risk factor for LPTS
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