203 research outputs found
Peanut Protein Hydrolysate: Its ACE-Inhibitory Activity and Secondary Structure as Affected by Simulated Gastrointestinal Digestion
No full textHypertension is a global health concern, and food-derived bioactive peptides are being explored as safer alternatives to synthetic antihypertensive drugs. In our previous study, peanut protein hydrolysate (PPH), produced via Alcalase© hydrolysis, showed significant ACE- and renin-inhibitory activities, suggesting potential antihypertensive benefits. However, its bioactivity may be influenced by digestion. This study investigates the effects of simulated gastrointestinal digestion on PPH’s ACE-inhibitory activity and secondary structure. PPH was digested using pepsin and pancreatin separately or sequentially at varying enzyme concentrations and digestion times. The antihypertensive potential of the digests was evaluated by ACE-inhibitory activity, and structural changes were characterized by FTIR. Results indicated that longer digestion times and higher enzyme concentrations enhanced ACE inhibition, suggesting the formation of smaller bioactive peptides. SDS-PAGE revealed protein degradation and the presence of peptides resistant to digestion. FTIR spectra revealed significant changes in PPH’s secondary structure post-digestion, which may also contribute to enhanced bioactivity. These findings suggest that gastrointestinal digestion enhances PPH’s bioavailability and antihypertensive potential, highlighting the role of structural changes in bioactivity improvement. Thus, PPH may serve as a promising and safer alternative to conventional drugs for hypertension management.https://digital.library.ncat.edu/gradresearchsymposium25/1138/thumbnail.jp
Leading the African agenda or following the African consensus? South Africa's implementation of the African agenda in the United Nations Security Council
No full textIdentification of Allergenic Peanut Protein and Peptides Resistant to Alcalase Hydrolysis
No full textPeanut allergy is one of most severe and persistent food allergies. While Alcalase hydrolysis significantly reduces major allergenic proteins, residual allergenicity remains a concern. This study aimed to identify resistant proteins/peptides contributing to the allergenicity of extensively hydrolyzed peanut protein concentrate (PPC). Peanut protein concentrate (PPC) at concentration of 10% was hydrolyzed with 4% Alcalase for 2-8 hours. The degree of hydrolysis (DH) increased from 34.91% to 44.68% accompanied with decreased IgE-binding. However, the SDS-PAGE and Western blot of both supernatants and precipitates with pooled sera from 7 peanut sensitive patients confirmed the presence of resistant allergenic peptides in the extensively hydrolyzed PPC, particularly, the two proteins/peptides with molecular weights 22.5kDa and 12.65kDa. To further characterize these resistant proteins/peptides, gel samples of these two peptides were sent a commercial service lab for sequencing using liquid chromatography-mass spectrometry (LC-MS/MS). The sequences obtained do not match any sequences of the native proteins in the PPC. This suggests that they are the peptides formed during Alcalase hydrolysis of larger proteins. Findings indicate that Alcalase hydrolysis alone is insufficient to eliminate peanut allergenicity. Further strategies are necessary to break down or mask all immunoreactive epitopes, enhancing the safety of peanut-based products.https://digital.library.ncat.edu/gradresearchsymposium25/1139/thumbnail.jp
A Systematic Evaluation of Manet Routing Protocols over UDP and TCP in Multi-hop Wireless Network
No full textSTRATEGIES FOR THE PRESERVATION OF ELECTRONIC RECORDS IN UNIVERSITY LIBRARIES IN NIGERIA
No full textPage 1. 5th of October, 2018 ICERI2018 Local Organising Committee ABSTRACT ACCEPTANCE LETTER This is a confirmation that the abstract entitled: “STRATEGIES FOR THE PRESERVATION OF ELECTRONIC RECORDS IN UNIVERSITY LIBRARIES IN NIGERIA” Author(s): Promise Ilo, Michael Fagbohun, Jerome Idiegbeyan-Ose, Ugwunwa Esse, Nwanne Nwokeoma, Ifeakachuku Osinulu, Olajumoke Olawoyin, Oyeronke Adebayo has been accepted as ORAL presentation at ICERI2018. Name of event: ICERI2018 (11th annual International Conference of Education, Research and Innovation) Dates: 12th-14th of November, 2018 Place: Seville (Spain) Organising entity: IATED IATED Academy. email: [email protected] – Tel.: (+34) 96 344 62 37 – Fax: (+34) 96 206 59 18 iated.or
Ha-Joon Chang to give Annual Adedeji Lecture 2016
No full textThe 2016 Annual Adedeji Lecture will be delivered by renowned Development Economist Ha-Joon Chang and author of widely discussed policy books, most notably Kicking Away the Ladder and 23 Things They Don't Tell You About Capitalism, and Economics. Chang’s new book Smart Industrial Policy for Africa in the 21st century will be launched alongside the 2016 Economic Report on Africa on 3rd April during the ECA-AU Africa Development Week. ECA launched the Adebayo Adedeji lecture series in March 2014 to honour and recognize the intellectual contribution to development, service to Africa and humanity of Professor Adebayo Adedeji ECA Executive Secretary from 1975-1978 and UN Under-Secretary General from 1978-1991
The program of physical education and its effect on the primary health care in selected secondary schools in Lagos state, 1990
No full textThe benefits derived from taking part in Physical Education lessons were directly related to the health of the school age children. The component of Education, such as physical, social, mental, and emotional aspects have been related to the growth and development of the individual child to maintain a healthy state. In the schools, one of the ways to achieve this goal is through the Physical Education program which is also an aspect of the School Health Program. It is also a part of Basic Health Care Program. This appraisal of health of the school children has been in operation for a long time in Lagos State Secondary Schools. However, there is a new global change from Basic Health Care to Primary Health Care. It was on this basis that this work was designed to look into the new health area and determine the contribution of Physical Education program to Primary Health Care. 12 schools were used in this study. Questionnaires were sent to selected schools in Lagos State and to some medical officers in some Local Government Areas of the state. The 240 school respondents and the 70 medical and para-medical respondents indicated among other things that the program of Physical Education was reflected in the Primary Health Care in Lagos State Secondary Schools
Working mothers' attitudes toward domestic and work roles a case study of some working mothers in Nigeria, 1984
No full textThis study aimed to determine mothers' attitudes toward occupa-tional work roles and domestic roles in Bida, Nigeria. The variables used were feelings of life satisfaction, job status, attitudes toward occupational work roles, a wife's perceptions of her husband's attitude toward her work roles and attitudes toward domestic work roles. Systematic random sampling was used to select the study group for this research. A sample of sixty (60) working mothers was selected out of a population of one hundred and twenty (120) at the Federal Poly�technic, Bida, Nigeria. The questionnaire used for data collection had three sub-scales which measured the mother's attitudes toward employment and domestic work roles, and the strain which may be generated by the interaction between members of this role set. The main findings of the survey showed that there was a signifi-cant difference between the attitudes of professional and non-professional mothers. The non-professional mothers tend to show that their families take all that they do at home for granted. Also, there was a strong relationship between job status and the feeling that the family appre�ciates all that a mother does at home. There was no significant relationship between life satisfaction and attitudes toward occupational roles, but there was a significant relationship between a mother's working hours that do not allow for her child care and her belief that her boss takes the work she does for granted. However, there was no significant relationship between a wife's perception of her husband's attitude toward her work roles and her home role attitudes. It is concluded that among the sample of women used in this study, job status has no relevance to their attitudes toward the roles the mothers perform at home. However, there is a relationship between job status and family appreciation of what a mother does at home. Finally, the findings showed that attitudes toward occupational work roles have no relationship with feelings of life satisfaction
“Outrageous, Audacious, Courageous, [and] Willful”: A Womanist approach to re-imagining resistance in public Black education, 2021
No full textThis study investigates the instructional traditions of three black women educators in South Carolina from 1862, when the first school for formerly enslaved Africans was established, to 1951, during the onset of the statewide “equalization schools'' campaign. Conceptualization of the instructional methods of black women establishes a historical context for black women educators as activists and serves as a counternarrative to the overwhelming dominant discourse of “whiteness” in education theory and praxis. Furthermore, it reveals ways in which these educators re-imagined the function of education through “everyday methods of problem-solving''. This study asserts that black women occupy a unique intersectional space, and as educators, especially, they can meaningfully and effectively contribute to pedagogy as a tool for resistance and empowerment. It further argues that the black women educators in this study primary educational approaches derived from a womanist framework, centering of black women’s perspectives, grassroots and collective agency, spiritual orientation, and the universality of rejecting systems of oppression including and beyond sexism. A qualitative narrative analysis of the subjects’ autobiographical publications, through a critical life history approach, is used to determine the characteristics of their instructional traits and the context that influenced them. The purpose of this research is to inform and contribute to current pedagogical practices and advocate for the canonization of instructional traditions of black theorists for teacher replication. Education inequity in the United States disproportionately affects black students, therefore, solutions specific to the educational needs and values of black communities are needed to address it
A comparison of CO2 emissions, load capacity factor, and ecological footprint for Thailand’s environmental sustainability
No full textThis study analyzes the determinants of carbon dioxide (CO2) emissions, ecological footprint, and load capacity factor for the first time by applying the Fourier quantile causality test to data for the period 1975q1–2018q4 for Thailand. In this context, the study investigates the validity of the pollution haven hypothesis (PHH) by comprehensively examining the effects of foreign direct investment, renewable energy, import, export, natural resources rent, and income on environmental quality. The findings of the study show that the validity of the PHH varies depending on the environmental indicators, because while the PHH is valid for the CO2 and the load capacity factor, it is not valid for the ecological footprint. Moreover, renewable energy is the only element that can increase the environmental quality. All other variables have a negative effect on the load capacity factor, which worsens the environmental quality. The results of the study suggest that the Thai government should take measures to regulate natural resources rent and foreign capital inflows by considering environmental concerns and promoting renewable resources
- …
